ClinVar Miner

Variants in gene NEXMIF with conflicting interpretations

Y axis minimum submission review status: Y axis collection method:
X axis minimum submission review status: X axis collection method:
Minimum conflict level:
Gene type:

If a variant has more than two submissions, it may have multiple conflicts and therefore be counted in more than one conflict column. If this is the case, the "Variants with any kind of conflict" cell will be less than the sum of the conflicted variants cells to its left.

Variants with only 1 submission per condition Variants with at least 2 submissions on the same condition and no conflicts Variants with a synonymous conflict
(e.g. benign vs non-pathogenic) 		Variants with a confidence conflict
(e.g. benign vs likely benign) 		Variants with a benign or likely benign vs uncertain conflict Variants with a category conflict
(e.g. benign vs affects) 		Variants with a clinically significant conflict
(e.g. benign vs pathogenic) 		Variants with any conflict
1038 188 0 74 56 0 1 121

Significance breakdown #

In the table below, cells that correspond to a term paired with itself represent synonymous conflicts, i.e. variants that have been annotated with different terms that map to the same standard term. To compare the terms that were actually submitted, check the box in the filters section at the top of this page.

pathogenic likely pathogenic uncertain significance likely benign benign
pathogenic 0 2 0 0 0
likely pathogenic 2 0 1 0 0
uncertain significance 0 1 0 43 24
likely benign 0 0 43 0 72
benign 0 0 24 72 0

All variants with conflicting interpretations #

Total variants: 121
Download table as spreadsheet
HGVS dbSNP gnomAD frequency
NM_001008537.3(NEXMIF):c.2598C>A (p.Ser866=) rs41298498 0.01502
NM_001008537.3(NEXMIF):c.151C>A (p.Pro51Thr) rs145018752 0.00666
NM_001008537.3(NEXMIF):c.3798C>T (p.Gly1266=) rs149185175 0.00527
NM_001008537.3(NEXMIF):c.3709A>T (p.Met1237Leu) rs61731613 0.00368
NM_001008537.3(NEXMIF):c.2373A>C (p.Thr791=) rs61742545 0.00315
NM_001008537.3(NEXMIF):c.4246C>T (p.Pro1416Ser) rs143577015 0.00258
NM_001008537.3(NEXMIF):c.3555G>T (p.Gly1185=) rs142714242 0.00075
NM_001008537.3(NEXMIF):c.4205A>G (p.Asn1402Ser) rs140532942 0.00061
NM_001008537.3(NEXMIF):c.2139G>A (p.Glu713=) rs139194076 0.00055
NM_001008537.3(NEXMIF):c.4509T>C (p.Pro1503=) rs41303725 0.00055
NM_001008537.3(NEXMIF):c.2098G>C (p.Val700Leu) rs141776597 0.00038
NM_001008537.3(NEXMIF):c.2505C>T (p.His835=) rs143453497 0.00038
NM_001008537.3(NEXMIF):c.133G>A (p.Ala45Thr) rs199960807 0.00030
NM_001008537.3(NEXMIF):c.1716G>T (p.Glu572Asp) rs148005156 0.00028
NM_001008537.3(NEXMIF):c.4320C>T (p.Asn1440=) rs769979162 0.00027
NM_001008537.3(NEXMIF):c.3775G>A (p.Ala1259Thr) rs761368099 0.00022
NM_001008537.3(NEXMIF):c.4048G>A (p.Asp1350Asn) rs200982385 0.00016
NM_001008537.3(NEXMIF):c.2315G>A (p.Arg772His) rs142822527 0.00015
NM_001008537.3(NEXMIF):c.206C>T (p.Ser69Phe) rs201351157 0.00014
NM_001008537.3(NEXMIF):c.3823A>G (p.Ser1275Gly) rs201434271 0.00012
NM_001008537.3(NEXMIF):c.42C>T (p.Asn14=) rs370708043 0.00012
NM_001008537.3(NEXMIF):c.4325C>T (p.Pro1442Leu) rs370429318 0.00012
NM_001008537.3(NEXMIF):c.4494C>T (p.Thr1498=) rs772871215 0.00012
NM_001008537.3(NEXMIF):c.3460C>A (p.Pro1154Thr) rs781129973 0.00011
NM_001008537.3(NEXMIF):c.357G>A (p.Glu119=) rs142318614 0.00011
NM_001008537.3(NEXMIF):c.475C>T (p.Pro159Ser) rs149980277 0.00011
NM_001008537.3(NEXMIF):c.1712G>A (p.Ser571Asn) rs372044888 0.00010
NM_001008537.3(NEXMIF):c.1854G>A (p.Glu618=) rs142687313 0.00010
NM_001008537.3(NEXMIF):c.2851G>A (p.Asp951Asn) rs771918287 0.00010
NM_001008537.3(NEXMIF):c.1749C>G (p.Pro583=) rs776062521 0.00009
NM_001008537.3(NEXMIF):c.2672A>G (p.Asn891Ser) rs186535459 0.00009
NM_001008537.3(NEXMIF):c.2849A>T (p.Tyr950Phe) rs373566578 0.00009
NM_001008537.3(NEXMIF):c.3402C>A (p.His1134Gln) rs138632224 0.00009
NM_001008537.3(NEXMIF):c.3753A>G (p.Ile1251Met) rs143365662 0.00009
NM_001008537.3(NEXMIF):c.4422G>A (p.Lys1474=) rs371190782 0.00009
NM_001008537.3(NEXMIF):c.4065C>T (p.Tyr1355=) rs755840617 0.00008
NM_001008537.3(NEXMIF):c.4446T>G (p.Phe1482Leu) rs770781682 0.00008
NM_001008537.3(NEXMIF):c.685G>T (p.Asp229Tyr) rs139459124 0.00008
NM_001008537.3(NEXMIF):c.1132A>G (p.Lys378Glu) rs61741844 0.00007
NM_001008537.3(NEXMIF):c.265C>T (p.His89Tyr) rs752314023 0.00007
NM_001008537.3(NEXMIF):c.3055G>A (p.Asp1019Asn) rs771299521 0.00007
NM_001008537.3(NEXMIF):c.3361C>T (p.Arg1121Trp) rs199579887 0.00007
NM_001008537.3(NEXMIF):c.4235G>A (p.Arg1412His) rs374045534 0.00007
NM_001008537.3(NEXMIF):c.3386T>G (p.Phe1129Cys) rs202207238 0.00006
NM_001008537.3(NEXMIF):c.2669C>T (p.Pro890Leu) rs377201508 0.00005
NM_001008537.3(NEXMIF):c.3650G>A (p.Arg1217His) rs143271748 0.00005
NM_001008537.3(NEXMIF):c.381G>A (p.Glu127=) rs148717498 0.00005
NM_001008537.3(NEXMIF):c.4406G>A (p.Arg1469Gln) rs151004644 0.00005
NM_001008537.3(NEXMIF):c.1261C>T (p.Leu421Phe) rs1320278331 0.00004
NM_001008537.3(NEXMIF):c.2130G>A (p.Lys710=) rs749479992 0.00004
NM_001008537.3(NEXMIF):c.262G>A (p.Glu88Lys) rs927047621 0.00004
NM_001008537.3(NEXMIF):c.2784C>G (p.Leu928=) rs754561437 0.00004
NM_001008537.3(NEXMIF):c.2966G>A (p.Arg989Gln) rs140836456 0.00004
NM_001008537.3(NEXMIF):c.3637G>A (p.Gly1213Ser) rs757442837 0.00004
NM_001008537.3(NEXMIF):c.4268G>A (p.Arg1423His) rs750153892 0.00004
NM_001008537.3(NEXMIF):c.4321G>A (p.Gly1441Arg) rs745720102 0.00004
NM_001008537.3(NEXMIF):c.4445T>C (p.Phe1482Ser) rs776659282 0.00004
NM_001008537.3(NEXMIF):c.4493C>A (p.Thr1498Asn) rs145525836 0.00004
NM_001008537.3(NEXMIF):c.91C>G (p.Gln31Glu) rs769243169 0.00004
NM_001008537.3(NEXMIF):c.1119G>C (p.Trp373Cys) rs780581302 0.00003
NM_001008537.3(NEXMIF):c.1161G>C (p.Glu387Asp) rs762881063 0.00003
NM_001008537.3(NEXMIF):c.153G>A (p.Pro51=) rs147096194 0.00003
NM_001008537.3(NEXMIF):c.2087G>T (p.Gly696Val) rs1270039330 0.00003
NM_001008537.3(NEXMIF):c.2147T>G (p.Val716Gly) rs1022775047 0.00003
NM_001008537.3(NEXMIF):c.2432C>T (p.Pro811Leu) rs750889767 0.00003
NM_001008537.3(NEXMIF):c.2544C>T (p.Thr848=) rs139924662 0.00003
NM_001008537.3(NEXMIF):c.3826C>G (p.Gln1276Glu) rs754763619 0.00003
NM_001008537.3(NEXMIF):c.4043A>G (p.His1348Arg) rs779047497 0.00003
NM_001008537.3(NEXMIF):c.1418C>T (p.Ser473Phe) rs1305966854 0.00002
NM_001008537.3(NEXMIF):c.1883G>A (p.Arg628Gln) rs747436946 0.00002
NM_001008537.3(NEXMIF):c.2311T>C (p.Ser771Pro) rs1569335460 0.00002
NM_001008537.3(NEXMIF):c.2357C>G (p.Thr786Ser) rs1450517934 0.00002
NM_001008537.3(NEXMIF):c.2986A>G (p.Met996Val) rs779441513 0.00002
NM_001008537.3(NEXMIF):c.3191G>A (p.Arg1064His) rs770464262 0.00002
NM_001008537.3(NEXMIF):c.3319G>A (p.Asp1107Asn) rs751468762 0.00002
NM_001008537.3(NEXMIF):c.3559A>G (p.Met1187Val) rs201176982 0.00002
NM_001008537.3(NEXMIF):c.3728G>A (p.Arg1243His) rs1256402686 0.00002
NM_001008537.3(NEXMIF):c.1196A>G (p.Asp399Gly) rs776363168 0.00001
NM_001008537.3(NEXMIF):c.1520G>A (p.Arg507Lys) rs778472603 0.00001
NM_001008537.3(NEXMIF):c.1757G>C (p.Gly586Ala) rs776845564 0.00001
NM_001008537.3(NEXMIF):c.1786A>G (p.Asn596Asp) rs1404043155 0.00001
NM_001008537.3(NEXMIF):c.1796C>T (p.Thr599Met) rs1052758203 0.00001
NM_001008537.3(NEXMIF):c.1841C>G (p.Pro614Arg) rs1165543381 0.00001
NM_001008537.3(NEXMIF):c.2088C>T (p.Gly696=) rs1227333624 0.00001
NM_001008537.3(NEXMIF):c.2521A>G (p.Asn841Asp) rs2147440160 0.00001
NM_001008537.3(NEXMIF):c.2720A>C (p.Glu907Ala) rs746824207 0.00001
NM_001008537.3(NEXMIF):c.3288G>A (p.Lys1096=) rs376193494 0.00001
NM_001008537.3(NEXMIF):c.3294C>T (p.Phe1098=) rs756252858 0.00001
NM_001008537.3(NEXMIF):c.3304G>A (p.Val1102Ile) rs750439376 0.00001
NM_001008537.3(NEXMIF):c.3323G>A (p.Ser1108Asn) rs763992609 0.00001
NM_001008537.3(NEXMIF):c.3371A>T (p.Gln1124Leu) rs992677972 0.00001
NM_001008537.3(NEXMIF):c.3479A>G (p.Asn1160Ser) rs764370545 0.00001
NM_001008537.3(NEXMIF):c.361G>T (p.Ala121Ser) rs769778503 0.00001
NM_001008537.3(NEXMIF):c.370G>A (p.Ala124Thr) rs781426673 0.00001
NM_001008537.3(NEXMIF):c.3927C>A (p.Asp1309Glu) rs938623851 0.00001
NM_001008537.3(NEXMIF):c.4012A>G (p.Ile1338Val) rs1297277744 0.00001
NM_001008537.3(NEXMIF):c.419T>C (p.Met140Thr) rs766172626 0.00001
NM_001008537.3(NEXMIF):c.4217C>A (p.Ala1406Glu) rs775633155 0.00001
NM_001008537.3(NEXMIF):c.431G>A (p.Arg144Gln) rs1029069870 0.00001
NM_001008537.3(NEXMIF):c.653G>A (p.Arg218Gln) rs747496798 0.00001
NM_001008537.3(NEXMIF):c.690G>A (p.Pro230=) rs776754896 0.00001
NM_001008537.3(NEXMIF):c.764A>G (p.Asn255Ser) rs369569825 0.00001
NM_001008537.3(NEXMIF):c.1154G>A (p.Gly385Asp) rs375109305
NM_001008537.3(NEXMIF):c.136C>T (p.Pro46Ser) rs762483701
NM_001008537.3(NEXMIF):c.1378A>G (p.Ser460Gly) rs1004870160
NM_001008537.3(NEXMIF):c.154G>A (p.Val52Met) rs747414246
NM_001008537.3(NEXMIF):c.1882C>T (p.Arg628Ter) rs786205208
NM_001008537.3(NEXMIF):c.1998AGA[1] (p.Glu667del) rs764439412
NM_001008537.3(NEXMIF):c.2394A>T (p.Leu798Phe) rs1159680987
NM_001008537.3(NEXMIF):c.2795C>G (p.Thr932Arg) rs375607660
NM_001008537.3(NEXMIF):c.2849A>G (p.Tyr950Cys) rs373566578
NM_001008537.3(NEXMIF):c.3302G>C (p.Gly1101Ala) rs1388842555
NM_001008537.3(NEXMIF):c.3325G>A (p.Val1109Met) rs948687949
NM_001008537.3(NEXMIF):c.3347G>C (p.Cys1116Ser) rs2080102020
NM_001008537.3(NEXMIF):c.3439G>C (p.Val1147Leu) rs1569335080
NM_001008537.3(NEXMIF):c.3481G>T (p.Asp1161Tyr) rs1281329703
NM_001008537.3(NEXMIF):c.3638G>A (p.Gly1213Asp) rs1602210996
NM_001008537.3(NEXMIF):c.4004T>C (p.Met1335Thr) rs374471570
NM_001008537.3(NEXMIF):c.67G>A (p.Val23Ile) rs766451802
NM_001008537.3(NEXMIF):c.694C>T (p.Gln232Ter) rs2080116822
NM_001008537.3(NEXMIF):c.864AGA[1] (p.Glu289del) rs2080115947

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