ClinVar Miner

Variants from University of Science and Technology Houari Boumediene, Laboratory of Molecular and Cellular Biology (LBCM)

Location: Algeria  Primary collection method: clinical testing
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign total
44 5 22 2 5 78

Gene and significance breakdown #

Total genes and gene combinations: 23
Download table as spreadsheet
Gene or gene combination pathogenic likely pathogenic uncertain significance likely benign benign total
BRCA2 6 0 15 2 3 26
APC 13 0 0 0 0 13
BRCA1 8 0 3 0 2 13
MLH1 4 0 0 0 0 4
MSH2 2 0 0 0 0 2
SPAST 1 1 0 0 0 2
SPG11 2 0 0 0 0 2
AMFR 0 1 0 0 0 1
AP4M1 1 0 0 0 0 1
AP4S1 1 0 0 0 0 1
ATL1 1 0 0 0 0 1
ATP13A2 1 0 0 0 0 1
BMPR1A 1 0 0 0 0 1
BRCA1, LOC126862571 0 0 1 0 0 1
CYP2U1 1 0 0 0 0 1
DDHD2 1 0 0 0 0 1
GBA2 1 0 0 0 0 1
HPDL, LOC129930440 0 1 0 0 0 1
MSH6 0 1 0 0 0 1
PALB2 0 0 1 0 0 1
PMS2 0 0 1 0 0 1
TP53 0 1 0 0 0 1
USP8 0 0 1 0 0 1

Condition and significance breakdown #

Total conditions: 20
Download table as spreadsheet
Condition pathogenic likely pathogenic uncertain significance likely benign benign total
Breast-ovarian cancer, familial, susceptibility to, 2 5 0 15 2 3 25
Breast-ovarian cancer, familial, susceptibility to, 1 9 0 5 0 2 16
Familial adenomatous polyposis 1 13 0 0 0 0 13
Lynch syndrome 1 6 1 1 0 0 8
Hereditary spastic paraplegia 11 2 0 0 0 0 2
Autosomal recessive spastic paraplegia type 59 0 0 1 0 0 1
Hereditary breast ovarian cancer syndrome 1 0 0 0 0 1
Hereditary spastic paraplegia 0 1 0 0 0 1
Hereditary spastic paraplegia 3A 1 0 0 0 0 1
Hereditary spastic paraplegia 4 1 0 0 0 0 1
Hereditary spastic paraplegia 46 1 0 0 0 0 1
Hereditary spastic paraplegia 50 1 0 0 0 0 1
Hereditary spastic paraplegia 52 1 0 0 0 0 1
Hereditary spastic paraplegia 54 1 0 0 0 0 1
Hereditary spastic paraplegia 56 1 0 0 0 0 1
Juvenile polyposis syndrome 1 0 0 0 0 1
Kufor-Rakeb syndrome 1 0 0 0 0 1
Li-Fraumeni syndrome 1 0 1 0 0 0 1
Spastic paraplegia 83, autosomal recessive 0 1 0 0 0 1
Spastic paraplegia 89, autosomal recessive 0 1 0 0 0 1

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. The submitted information has not been verified. If you have questions about the information contained on this website, please see a health care professional.