If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.
| pathogenic | likely pathogenic | uncertain significance | likely benign | benign | association | total |
|---|---|---|---|---|---|---|
| 84 | 345 | 370 | 0 | 0 | 1 | 800 |
Gene and significance breakdown #
| Gene or gene combination | pathogenic | likely pathogenic | uncertain significance | association | total |
|---|---|---|---|---|---|
| DMD | 4 | 9 | 1 | 0 | 14 |
| TTN | 0 | 7 | 2 | 0 | 9 |
| FKRP | 0 | 0 | 6 | 0 | 6 |
| GNE | 0 | 3 | 3 | 0 | 6 |
| SCN1A | 2 | 2 | 1 | 0 | 5 |
| ATP7B | 0 | 3 | 1 | 0 | 4 |
| COL6A2 | 2 | 2 | 0 | 0 | 4 |
| DYSF | 3 | 1 | 0 | 0 | 4 |
| LOC102724058, SCN1A | 1 | 3 | 0 | 0 | 4 |
| PKD1 | 2 | 1 | 1 | 0 | 4 |
| ABCC8 | 1 | 1 | 1 | 0 | 3 |
| CACNA1G | 0 | 0 | 3 | 0 | 3 |
| CFTR | 0 | 2 | 1 | 0 | 3 |
| CLN6 | 0 | 3 | 0 | 0 | 3 |
| COL7A1 | 0 | 3 | 0 | 0 | 3 |
| FGFR1 | 0 | 0 | 3 | 0 | 3 |
| FHOD3 | 0 | 0 | 3 | 0 | 3 |
| HPS1 | 1 | 1 | 1 | 0 | 3 |
| KCNJ11 | 0 | 2 | 1 | 0 | 3 |
| KCNN2 | 0 | 0 | 3 | 0 | 3 |
| LRBA | 0 | 1 | 2 | 0 | 3 |
| MYBPC3 | 0 | 1 | 2 | 0 | 3 |
| OCA2 | 0 | 1 | 2 | 0 | 3 |
| PDHA1 | 0 | 1 | 2 | 0 | 3 |
| PIGN | 0 | 2 | 1 | 0 | 3 |
| PKHD1 | 0 | 0 | 3 | 0 | 3 |
| RYR2 | 0 | 0 | 3 | 0 | 3 |
| SAMD9 | 0 | 1 | 2 | 0 | 3 |
| SCN2A | 1 | 1 | 1 | 0 | 3 |
| SETX | 1 | 2 | 0 | 0 | 3 |
| SH3TC2 | 0 | 1 | 2 | 0 | 3 |
| SLC19A3 | 0 | 2 | 1 | 0 | 3 |
| TRPM6 | 2 | 1 | 0 | 0 | 3 |
| TUBB4A | 0 | 0 | 3 | 0 | 3 |
| TYK2 | 0 | 1 | 2 | 0 | 3 |
| WFS1 | 0 | 1 | 2 | 0 | 3 |
| AAAS | 0 | 2 | 0 | 0 | 2 |
| ABCC2 | 0 | 1 | 1 | 0 | 2 |
| ALDH3A2 | 1 | 0 | 1 | 0 | 2 |
| ANK1 | 0 | 1 | 1 | 0 | 2 |
| AP5Z1 | 0 | 0 | 2 | 0 | 2 |
| ASAH1 | 0 | 2 | 0 | 0 | 2 |
| ATP13A2 | 0 | 1 | 1 | 0 | 2 |
| ATP8B1 | 0 | 0 | 2 | 0 | 2 |
| AVIL | 0 | 0 | 2 | 0 | 2 |
| BCKDHB | 0 | 1 | 1 | 0 | 2 |
| CACNA1A | 0 | 0 | 2 | 0 | 2 |
| CAPN3 | 0 | 1 | 1 | 0 | 2 |
| CDH1 | 0 | 0 | 2 | 0 | 2 |
| CEL | 0 | 1 | 1 | 0 | 2 |
| CFAP74 | 0 | 2 | 0 | 0 | 2 |
| CHD7 | 0 | 1 | 1 | 0 | 2 |
| CIAO1 | 0 | 0 | 2 | 0 | 2 |
| CLCN1 | 0 | 2 | 0 | 0 | 2 |
| COX15 | 0 | 1 | 1 | 0 | 2 |
| CPS1 | 0 | 1 | 1 | 0 | 2 |
| CTSK | 0 | 1 | 1 | 0 | 2 |
| CYP11A1 | 0 | 1 | 1 | 0 | 2 |
| CYP11B1, LOC106799833 | 0 | 0 | 2 | 0 | 2 |
| CYP27B1 | 1 | 0 | 1 | 0 | 2 |
| DEPDC5 | 0 | 0 | 2 | 0 | 2 |
| DNAH7 | 0 | 2 | 0 | 0 | 2 |
| DOCK7 | 0 | 0 | 2 | 0 | 2 |
| DOCK8 | 0 | 0 | 2 | 0 | 2 |
| EDNRB | 0 | 0 | 2 | 0 | 2 |
| EPRS1 | 0 | 0 | 2 | 0 | 2 |
| ERCC6 | 1 | 1 | 0 | 0 | 2 |
| EXT1 | 2 | 0 | 0 | 0 | 2 |
| F13A1 | 0 | 2 | 0 | 0 | 2 |
| F7 | 1 | 1 | 0 | 0 | 2 |
| FDFT1 | 0 | 1 | 1 | 0 | 2 |
| FERMT1 | 1 | 1 | 0 | 0 | 2 |
| FGD4 | 0 | 1 | 1 | 0 | 2 |
| FPGT-TNNI3K, TNNI3K | 0 | 1 | 1 | 0 | 2 |
| GABBR2 | 0 | 1 | 1 | 0 | 2 |
| GALK1, ITGB4 | 0 | 1 | 1 | 0 | 2 |
| GFM1 | 0 | 0 | 2 | 0 | 2 |
| GHR | 0 | 0 | 2 | 0 | 2 |
| GPT2 | 0 | 1 | 1 | 0 | 2 |
| GUCY2C | 0 | 2 | 0 | 0 | 2 |
| HPS4 | 0 | 2 | 0 | 0 | 2 |
| HSD17B4 | 0 | 0 | 2 | 0 | 2 |
| HYDIN | 0 | 2 | 0 | 0 | 2 |
| IQSEC2 | 0 | 1 | 1 | 0 | 2 |
| IRF2BPL | 0 | 2 | 0 | 0 | 2 |
| LAMA2 | 1 | 1 | 0 | 0 | 2 |
| LDB3 | 0 | 0 | 2 | 0 | 2 |
| LMAN1 | 1 | 0 | 1 | 0 | 2 |
| LOC126861897, MHRT, MYH7 | 0 | 0 | 2 | 0 | 2 |
| MACF1 | 0 | 0 | 2 | 0 | 2 |
| MECP2 | 0 | 2 | 0 | 0 | 2 |
| MFN2 | 0 | 0 | 2 | 0 | 2 |
| MFSD8 | 1 | 1 | 0 | 0 | 2 |
| MT-ND5 | 0 | 0 | 2 | 0 | 2 |
| MYH7B | 0 | 1 | 1 | 0 | 2 |
| MYO15A | 1 | 0 | 1 | 0 | 2 |
| NAGLU | 0 | 0 | 2 | 0 | 2 |
| NBEA | 0 | 1 | 1 | 0 | 2 |
| NCR1, NLRP7 | 0 | 1 | 1 | 0 | 2 |
| NEB, RIF1 | 0 | 1 | 1 | 0 | 2 |
| NF1 | 1 | 1 | 0 | 0 | 2 |
| NHLRC1 | 0 | 2 | 0 | 0 | 2 |
| NOTCH2 | 0 | 1 | 1 | 0 | 2 |
| OGDHL | 0 | 0 | 2 | 0 | 2 |
| OPA1 | 0 | 2 | 0 | 0 | 2 |
| PCYT2 | 0 | 0 | 2 | 0 | 2 |
| PKLR | 0 | 1 | 1 | 0 | 2 |
| PLAA | 0 | 1 | 1 | 0 | 2 |
| PLEC | 0 | 2 | 0 | 0 | 2 |
| PLEKHG2 | 0 | 0 | 2 | 0 | 2 |
| POLR1A | 0 | 0 | 2 | 0 | 2 |
| RP9 | 0 | 1 | 1 | 0 | 2 |
| RPGR | 0 | 2 | 0 | 0 | 2 |
| RYR1 | 0 | 0 | 2 | 0 | 2 |
| SARS1 | 0 | 1 | 1 | 0 | 2 |
| SGCA | 0 | 0 | 2 | 0 | 2 |
| SGCG | 1 | 1 | 0 | 0 | 2 |
| SLC16A2 | 1 | 1 | 0 | 0 | 2 |
| SLC2A1 | 1 | 1 | 0 | 0 | 2 |
| SLC2A9 | 0 | 1 | 1 | 0 | 2 |
| SNHG14, UBE3A | 0 | 2 | 0 | 0 | 2 |
| SPTBN2 | 0 | 1 | 1 | 0 | 2 |
| SPTBN4 | 0 | 0 | 2 | 0 | 2 |
| SRD5A2 | 2 | 0 | 0 | 0 | 2 |
| STK36 | 0 | 0 | 2 | 0 | 2 |
| SYNE2 | 0 | 2 | 0 | 0 | 2 |
| SZT2 | 0 | 0 | 2 | 0 | 2 |
| TCIRG1 | 1 | 1 | 0 | 0 | 2 |
| TP53 | 0 | 2 | 0 | 0 | 2 |
| TRRAP | 0 | 0 | 2 | 0 | 2 |
| TSC2 | 0 | 2 | 0 | 0 | 2 |
| TUBA1A | 0 | 0 | 2 | 0 | 2 |
| ABCA12, SNHG31 | 0 | 0 | 1 | 0 | 1 |
| ABCA4 | 0 | 1 | 0 | 0 | 1 |
| ABCB11 | 0 | 0 | 1 | 0 | 1 |
| ABCD1 | 1 | 0 | 0 | 0 | 1 |
| ABL1 | 0 | 0 | 1 | 0 | 1 |
| ACE | 0 | 0 | 1 | 0 | 1 |
| ACOX1 | 1 | 0 | 0 | 0 | 1 |
| ACTL6B | 0 | 1 | 0 | 0 | 1 |
| ACTN2 | 1 | 0 | 0 | 0 | 1 |
| ADAMTS9 | 0 | 0 | 1 | 0 | 1 |
| ADGRG1 | 0 | 0 | 1 | 0 | 1 |
| ADGRV1 | 0 | 0 | 1 | 0 | 1 |
| ADPRS | 0 | 1 | 0 | 0 | 1 |
| ADSL | 0 | 1 | 0 | 0 | 1 |
| AFG2B | 0 | 0 | 1 | 0 | 1 |
| AFG3L2 | 0 | 1 | 0 | 0 | 1 |
| AGL | 0 | 1 | 0 | 0 | 1 |
| AGTPBP1 | 0 | 1 | 0 | 0 | 1 |
| AHI1 | 0 | 0 | 1 | 0 | 1 |
| ALG13 | 0 | 0 | 1 | 0 | 1 |
| ALMS1 | 0 | 1 | 0 | 0 | 1 |
| ALOX12B | 0 | 0 | 1 | 0 | 1 |
| ALOXE3, LOC126862485 | 0 | 0 | 1 | 0 | 1 |
| ALPL | 0 | 0 | 1 | 0 | 1 |
| ALS2 | 0 | 1 | 0 | 0 | 1 |
| AMH | 0 | 0 | 1 | 0 | 1 |
| AMN | 0 | 1 | 0 | 0 | 1 |
| AMPD2 | 0 | 1 | 0 | 0 | 1 |
| ANK3 | 0 | 0 | 1 | 0 | 1 |
| ANO3 | 0 | 0 | 1 | 0 | 1 |
| ANTXR1 | 0 | 0 | 1 | 0 | 1 |
| ARFGEF1 | 0 | 1 | 0 | 0 | 1 |
| ARHGEF10 | 0 | 0 | 1 | 0 | 1 |
| ARID1B | 0 | 1 | 0 | 0 | 1 |
| ARSA | 0 | 1 | 0 | 0 | 1 |
| ARSG | 0 | 1 | 0 | 0 | 1 |
| ARSL | 0 | 1 | 0 | 0 | 1 |
| ARX, LOC109610631 | 0 | 0 | 1 | 0 | 1 |
| ASNS, CZ1P-ASNS | 0 | 0 | 1 | 0 | 1 |
| ASPH | 1 | 0 | 0 | 0 | 1 |
| ASS1 | 0 | 1 | 0 | 0 | 1 |
| ASXL1 | 0 | 0 | 1 | 0 | 1 |
| ASXL3 | 0 | 1 | 0 | 0 | 1 |
| ATM | 0 | 1 | 0 | 0 | 1 |
| ATP1A2 | 0 | 1 | 0 | 0 | 1 |
| ATP1A3 | 0 | 0 | 1 | 0 | 1 |
| ATP6V0A4 | 1 | 0 | 0 | 0 | 1 |
| ATP6V1A | 0 | 0 | 1 | 0 | 1 |
| AUTS2 | 0 | 1 | 0 | 0 | 1 |
| B3GALT6 | 0 | 0 | 1 | 0 | 1 |
| BBS2 | 0 | 0 | 1 | 0 | 1 |
| BBS9 | 0 | 1 | 0 | 0 | 1 |
| BEST1 | 0 | 0 | 1 | 0 | 1 |
| BMP15 | 0 | 1 | 0 | 0 | 1 |
| BMP6 | 0 | 0 | 1 | 0 | 1 |
| BSCL2, HNRNPUL2-BSCL2 | 0 | 0 | 1 | 0 | 1 |
| C14orf39, SIX6 | 0 | 1 | 0 | 0 | 1 |
| C17orf107, CHRNE | 0 | 0 | 1 | 0 | 1 |
| C2orf69 | 0 | 0 | 1 | 0 | 1 |
| CA1 | 0 | 0 | 1 | 0 | 1 |
| CACNA1H | 0 | 0 | 1 | 0 | 1 |
| CACNB2 | 0 | 1 | 0 | 0 | 1 |
| CAD | 0 | 0 | 1 | 0 | 1 |
| CAPN1 | 1 | 0 | 0 | 0 | 1 |
| CAPN10 | 0 | 1 | 0 | 0 | 1 |
| CASD1, SGCE | 1 | 0 | 0 | 0 | 1 |
| CASK | 0 | 1 | 0 | 0 | 1 |
| CASQ1 | 0 | 1 | 0 | 0 | 1 |
| CATIP, PNKD | 0 | 0 | 1 | 0 | 1 |
| CDK10 | 1 | 0 | 0 | 0 | 1 |
| CDK8 | 0 | 0 | 1 | 0 | 1 |
| CDKL5 | 0 | 1 | 0 | 0 | 1 |
| CELF2 | 0 | 0 | 1 | 0 | 1 |
| CENPF | 0 | 0 | 1 | 0 | 1 |
| CEP290 | 0 | 0 | 1 | 0 | 1 |
| CFAP96, UFSP2 | 0 | 1 | 0 | 0 | 1 |
| CFH | 0 | 1 | 0 | 0 | 1 |
| CFTR, LOC111674472 | 1 | 0 | 0 | 0 | 1 |
| CHD4 | 0 | 1 | 0 | 0 | 1 |
| CHFR | 0 | 1 | 0 | 0 | 1 |
| CHKB, CHKB-CPT1B | 0 | 0 | 1 | 0 | 1 |
| CHRNA1 | 0 | 0 | 1 | 0 | 1 |
| CHRNA4 | 0 | 1 | 0 | 0 | 1 |
| CHRNB2 | 0 | 0 | 1 | 0 | 1 |
| CLCN7 | 0 | 1 | 0 | 0 | 1 |
| CLDN10 | 0 | 0 | 1 | 0 | 1 |
| CLEC7A | 0 | 0 | 1 | 0 | 1 |
| CNGB1 | 0 | 0 | 1 | 0 | 1 |
| CNGB3 | 0 | 0 | 1 | 0 | 1 |
| CNOT1 | 0 | 1 | 0 | 0 | 1 |
| CNTN6 | 0 | 1 | 0 | 0 | 1 |
| CNTNAP1 | 0 | 1 | 0 | 0 | 1 |
| COL11A1 | 0 | 1 | 0 | 0 | 1 |
| COL18A1 | 0 | 0 | 1 | 0 | 1 |
| COL1A1 | 0 | 1 | 0 | 0 | 1 |
| COL25A1 | 0 | 1 | 0 | 0 | 1 |
| COL27A1 | 0 | 1 | 0 | 0 | 1 |
| COL4A4 | 0 | 1 | 0 | 0 | 1 |
| COL6A1 | 0 | 1 | 0 | 0 | 1 |
| COL6A3, LOC122889011 | 1 | 0 | 0 | 0 | 1 |
| CORIN | 0 | 1 | 0 | 0 | 1 |
| CPE | 0 | 1 | 0 | 0 | 1 |
| CPT1C | 0 | 1 | 0 | 0 | 1 |
| CPT2 | 0 | 0 | 1 | 0 | 1 |
| CR1 | 0 | 0 | 1 | 0 | 1 |
| CREBBP | 0 | 0 | 1 | 0 | 1 |
| CSF1R | 1 | 0 | 0 | 0 | 1 |
| CTCF | 0 | 1 | 0 | 0 | 1 |
| CTNNA3 | 0 | 1 | 0 | 0 | 1 |
| CTNS | 0 | 1 | 0 | 0 | 1 |
| CUBN | 0 | 1 | 0 | 0 | 1 |
| CUL7 | 0 | 1 | 0 | 0 | 1 |
| CYP11B1 | 0 | 0 | 1 | 0 | 1 |
| CYP21A2, LOC106780800 | 0 | 1 | 0 | 0 | 1 |
| CYP27A1 | 0 | 1 | 0 | 0 | 1 |
| DARS2 | 0 | 0 | 1 | 0 | 1 |
| DBT | 0 | 1 | 0 | 0 | 1 |
| DEAF1 | 0 | 1 | 0 | 0 | 1 |
| DES | 0 | 0 | 1 | 0 | 1 |
| DGKE | 0 | 1 | 0 | 0 | 1 |
| DHODH | 0 | 0 | 1 | 0 | 1 |
| DHX37 | 0 | 0 | 1 | 0 | 1 |
| DISP1 | 0 | 1 | 0 | 0 | 1 |
| DKC1 | 0 | 1 | 0 | 0 | 1 |
| DLL4 | 0 | 1 | 0 | 0 | 1 |
| DNAH11 | 0 | 0 | 1 | 0 | 1 |
| DNAH14 | 0 | 1 | 0 | 0 | 1 |
| DNAJB6 | 0 | 1 | 0 | 0 | 1 |
| DNAJC30 | 0 | 0 | 1 | 0 | 1 |
| DNAJC6 | 0 | 1 | 0 | 0 | 1 |
| DNM1L | 0 | 0 | 1 | 0 | 1 |
| DNM2 | 0 | 0 | 1 | 0 | 1 |
| DOK7 | 1 | 0 | 0 | 0 | 1 |
| DPH2 | 0 | 0 | 1 | 0 | 1 |
| DPH2, LOC126805726 | 0 | 1 | 0 | 0 | 1 |
| DRP2 | 0 | 0 | 1 | 0 | 1 |
| DSC2 | 0 | 1 | 0 | 0 | 1 |
| ECEL1 | 0 | 1 | 0 | 0 | 1 |
| EDA | 0 | 1 | 0 | 0 | 1 |
| EDEM3 | 0 | 1 | 0 | 0 | 1 |
| EFHC1 | 0 | 0 | 1 | 0 | 1 |
| EFNB1 | 1 | 0 | 0 | 0 | 1 |
| EGR2 | 0 | 1 | 0 | 0 | 1 |
| EIF2B3 | 0 | 1 | 0 | 0 | 1 |
| EPCAM | 0 | 0 | 1 | 0 | 1 |
| ERCC2 | 0 | 1 | 0 | 0 | 1 |
| ERMARD | 0 | 1 | 0 | 0 | 1 |
| EYA1 | 0 | 1 | 0 | 0 | 1 |
| FA2H | 0 | 1 | 0 | 0 | 1 |
| FAM20A, PRKAR1A | 0 | 1 | 0 | 0 | 1 |
| FBLN5 | 1 | 0 | 0 | 0 | 1 |
| FBN1 | 1 | 0 | 0 | 0 | 1 |
| FGD1 | 0 | 1 | 0 | 0 | 1 |
| FGF13 | 0 | 0 | 1 | 0 | 1 |
| FGFR3 | 0 | 0 | 1 | 0 | 1 |
| FH | 0 | 1 | 0 | 0 | 1 |
| FIG4 | 0 | 1 | 0 | 0 | 1 |
| FLCN | 0 | 0 | 1 | 0 | 1 |
| FLNA | 0 | 0 | 1 | 0 | 1 |
| FLNB | 0 | 0 | 1 | 0 | 1 |
| FLNC | 0 | 1 | 0 | 0 | 1 |
| FLVCR1 | 0 | 1 | 0 | 0 | 1 |
| FOXG1 | 1 | 0 | 0 | 0 | 1 |
| FUZ | 0 | 0 | 0 | 1 | 1 |
| FXN | 0 | 1 | 0 | 0 | 1 |
| GABRA1 | 0 | 0 | 1 | 0 | 1 |
| GABRB2 | 0 | 0 | 1 | 0 | 1 |
| GAN | 0 | 0 | 1 | 0 | 1 |
| GANAB | 0 | 1 | 0 | 0 | 1 |
| GBA1, LOC106627981 | 0 | 0 | 1 | 0 | 1 |
| GBA2 | 0 | 1 | 0 | 0 | 1 |
| GCDH | 0 | 0 | 1 | 0 | 1 |
| GEMIN5 | 0 | 1 | 0 | 0 | 1 |
| GFPT1 | 0 | 1 | 0 | 0 | 1 |
| GJB1 | 0 | 1 | 0 | 0 | 1 |
| GJC2 | 0 | 0 | 1 | 0 | 1 |
| GLA, RPL36A-HNRNPH2 | 0 | 1 | 0 | 0 | 1 |
| GLUD1 | 0 | 1 | 0 | 0 | 1 |
| GNAS | 0 | 1 | 0 | 0 | 1 |
| GORAB | 0 | 1 | 0 | 0 | 1 |
| GRIA4 | 0 | 0 | 1 | 0 | 1 |
| GRM1 | 0 | 0 | 1 | 0 | 1 |
| GUCA1A, GUCA1ANB-GUCA1A | 0 | 0 | 1 | 0 | 1 |
| GUSB | 0 | 1 | 0 | 0 | 1 |
| HADH | 0 | 0 | 1 | 0 | 1 |
| HADHB | 0 | 0 | 1 | 0 | 1 |
| HBA-LCR, NPRL3 | 0 | 1 | 0 | 0 | 1 |
| HCFC1 | 0 | 0 | 1 | 0 | 1 |
| HGF | 0 | 0 | 1 | 0 | 1 |
| HGSNAT | 0 | 1 | 0 | 0 | 1 |
| HK1 | 0 | 1 | 0 | 0 | 1 |
| HMCN1 | 0 | 0 | 1 | 0 | 1 |
| HMMR | 0 | 0 | 1 | 0 | 1 |
| HNF1A | 0 | 1 | 0 | 0 | 1 |
| HNF1B | 0 | 0 | 1 | 0 | 1 |
| HOXD13 | 0 | 0 | 1 | 0 | 1 |
| HPDL | 0 | 0 | 1 | 0 | 1 |
| HSD3B2 | 0 | 0 | 1 | 0 | 1 |
| HSPG2 | 0 | 1 | 0 | 0 | 1 |
| HTRA1 | 0 | 1 | 0 | 0 | 1 |
| IDH3A | 0 | 0 | 1 | 0 | 1 |
| IDUA | 0 | 1 | 0 | 0 | 1 |
| IFIH1 | 0 | 0 | 1 | 0 | 1 |
| IFT88 | 0 | 0 | 1 | 0 | 1 |
| IGF2R | 0 | 0 | 1 | 0 | 1 |
| IGF2R, LOC129997612 | 0 | 0 | 1 | 0 | 1 |
| IGFALS | 0 | 0 | 1 | 0 | 1 |
| IHH | 0 | 0 | 1 | 0 | 1 |
| IRF2BPL, LOC107984638 | 0 | 1 | 0 | 0 | 1 |
| IRF6 | 1 | 0 | 0 | 0 | 1 |
| IRS2 | 0 | 0 | 1 | 0 | 1 |
| ITGA2B | 0 | 1 | 0 | 0 | 1 |
| ITGB3 | 0 | 0 | 1 | 0 | 1 |
| ITGB4 | 0 | 0 | 1 | 0 | 1 |
| ITPR1 | 0 | 0 | 1 | 0 | 1 |
| JAG1 | 1 | 0 | 0 | 0 | 1 |
| KARS1 | 0 | 0 | 1 | 0 | 1 |
| KARS1, LOC126862402 | 0 | 0 | 1 | 0 | 1 |
| KCNC2 | 0 | 0 | 1 | 0 | 1 |
| KCNJ1 | 0 | 1 | 0 | 0 | 1 |
| KCNJ10 | 0 | 1 | 0 | 0 | 1 |
| KCNQ2 | 0 | 0 | 1 | 0 | 1 |
| KCNQ3 | 0 | 0 | 1 | 0 | 1 |
| KCNT2 | 0 | 0 | 1 | 0 | 1 |
| KDM5C | 0 | 0 | 1 | 0 | 1 |
| KIF1B | 0 | 0 | 1 | 0 | 1 |
| KIF1C | 0 | 1 | 0 | 0 | 1 |
| KIF5B | 0 | 0 | 1 | 0 | 1 |
| KLF11 | 0 | 0 | 1 | 0 | 1 |
| KMT2C | 0 | 0 | 1 | 0 | 1 |
| KRT2 | 0 | 1 | 0 | 0 | 1 |
| LAMA1 | 1 | 0 | 0 | 0 | 1 |
| LAMA3 | 1 | 0 | 0 | 0 | 1 |
| LAMA5 | 0 | 0 | 1 | 0 | 1 |
| LDLR | 0 | 1 | 0 | 0 | 1 |
| LHX3 | 0 | 0 | 1 | 0 | 1 |
| LIG1 | 0 | 0 | 1 | 0 | 1 |
| LIPT1, MITD1 | 0 | 0 | 1 | 0 | 1 |
| LMNA | 0 | 1 | 0 | 0 | 1 |
| LMNA, LOC129931597 | 0 | 0 | 1 | 0 | 1 |
| LNPK | 0 | 0 | 1 | 0 | 1 |
| LOC100507346, PTCH1 | 0 | 1 | 0 | 0 | 1 |
| LOC107648851, TAP2 | 0 | 0 | 1 | 0 | 1 |
| LOC110121499, PISD | 0 | 1 | 0 | 0 | 1 |
| LOC126805704, SNIP1 | 0 | 1 | 0 | 0 | 1 |
| LOC126806798, ZNF148 | 0 | 1 | 0 | 0 | 1 |
| LOC129995449, SQSTM1 | 0 | 0 | 1 | 0 | 1 |
| LOC130004109, VCL | 0 | 0 | 1 | 0 | 1 |
| LOC130055387, NRL | 0 | 1 | 0 | 0 | 1 |
| LOC130061900, SGSH | 1 | 0 | 0 | 0 | 1 |
| LPAR6, RB1 | 1 | 0 | 0 | 0 | 1 |
| LPL | 0 | 1 | 0 | 0 | 1 |
| LRAT | 0 | 0 | 1 | 0 | 1 |
| LRP5 | 0 | 0 | 1 | 0 | 1 |
| LTBP4 | 0 | 0 | 1 | 0 | 1 |
| LYST | 1 | 0 | 0 | 0 | 1 |
| LZTR1 | 0 | 0 | 1 | 0 | 1 |
| MADD | 0 | 0 | 1 | 0 | 1 |
| MAGEL2 | 0 | 1 | 0 | 0 | 1 |
| MAP3K1 | 0 | 0 | 1 | 0 | 1 |
| MAP3K7 | 0 | 1 | 0 | 0 | 1 |
| MAST3 | 0 | 0 | 1 | 0 | 1 |
| MATN3 | 0 | 0 | 1 | 0 | 1 |
| MC1R | 1 | 0 | 0 | 0 | 1 |
| MC2R | 1 | 0 | 0 | 0 | 1 |
| MCM8 | 0 | 1 | 0 | 0 | 1 |
| MECR | 0 | 0 | 1 | 0 | 1 |
| MED13 | 0 | 0 | 1 | 0 | 1 |
| MED13L | 0 | 1 | 0 | 0 | 1 |
| MEGF10 | 0 | 0 | 1 | 0 | 1 |
| MERTK | 0 | 0 | 1 | 0 | 1 |
| MIP | 0 | 0 | 1 | 0 | 1 |
| MKKS | 0 | 0 | 1 | 0 | 1 |
| MLC1 | 1 | 0 | 0 | 0 | 1 |
| MLH1 | 1 | 0 | 0 | 0 | 1 |
| MOCOS | 0 | 0 | 1 | 0 | 1 |
| MOCS1 | 0 | 1 | 0 | 0 | 1 |
| MORC2 | 0 | 1 | 0 | 0 | 1 |
| MPZ | 0 | 0 | 1 | 0 | 1 |
| MSL3 | 0 | 1 | 0 | 0 | 1 |
| MT-ATP6 | 0 | 0 | 1 | 0 | 1 |
| MT-CYB | 0 | 0 | 1 | 0 | 1 |
| MT-ND6 | 0 | 0 | 1 | 0 | 1 |
| MT-TL1 | 0 | 0 | 1 | 0 | 1 |
| MT-TS2 | 0 | 0 | 1 | 0 | 1 |
| MUSK | 0 | 1 | 0 | 0 | 1 |
| MVP-DT, PRRT2 | 0 | 1 | 0 | 0 | 1 |
| MYH2, MYHAS | 0 | 0 | 1 | 0 | 1 |
| MYH6 | 0 | 0 | 1 | 0 | 1 |
| MYH7 | 0 | 1 | 0 | 0 | 1 |
| MYMK | 0 | 0 | 1 | 0 | 1 |
| MYOC | 0 | 1 | 0 | 0 | 1 |
| MYORG | 0 | 1 | 0 | 0 | 1 |
| NALCN | 0 | 1 | 0 | 0 | 1 |
| NAXD | 0 | 1 | 0 | 0 | 1 |
| NDNF | 0 | 0 | 1 | 0 | 1 |
| NDUFB3 | 0 | 0 | 1 | 0 | 1 |
| NDUFS1 | 0 | 1 | 0 | 0 | 1 |
| NEK10 | 0 | 1 | 0 | 0 | 1 |
| NF2 | 1 | 0 | 0 | 0 | 1 |
| NGF | 0 | 0 | 1 | 0 | 1 |
| NIPBL | 0 | 1 | 0 | 0 | 1 |
| NKX2-1, SFTA3 | 0 | 1 | 0 | 0 | 1 |
| NLRP1 | 0 | 0 | 1 | 0 | 1 |
| NNT | 0 | 1 | 0 | 0 | 1 |
| NOBOX | 0 | 0 | 1 | 0 | 1 |
| NOTCH3 | 0 | 1 | 0 | 0 | 1 |
| NPR3 | 0 | 1 | 0 | 0 | 1 |
| NR2E3 | 0 | 0 | 1 | 0 | 1 |
| NR5A1 | 0 | 1 | 0 | 0 | 1 |
| NRIP1 | 0 | 1 | 0 | 0 | 1 |
| NSD2 | 0 | 0 | 1 | 0 | 1 |
| NTRK1 | 0 | 0 | 1 | 0 | 1 |
| NTRK2 | 0 | 0 | 1 | 0 | 1 |
| NUP155 | 0 | 0 | 1 | 0 | 1 |
| OCRL | 0 | 1 | 0 | 0 | 1 |
| ODC1 | 0 | 1 | 0 | 0 | 1 |
| OFD1, TRAPPC2 | 1 | 0 | 0 | 0 | 1 |
| OPHN1 | 0 | 1 | 0 | 0 | 1 |
| OTOF | 1 | 0 | 0 | 0 | 1 |
| P3H1 | 1 | 0 | 0 | 0 | 1 |
| PCDHG@, PCDHGA1, PCDHGA10, PCDHGA11, PCDHGA12, PCDHGA2, PCDHGA3, PCDHGA4, PCDHGA5, PCDHGA6, PCDHGA7, PCDHGA8, PCDHGA9, PCDHGB1, PCDHGB2, PCDHGB3, PCDHGB4, PCDHGB5, PCDHGB6, PCDHGB7, PCDHGC3, PCDHGC4 | 0 | 1 | 0 | 0 | 1 |
| PCK1 | 0 | 1 | 0 | 0 | 1 |
| PDE10A | 0 | 1 | 0 | 0 | 1 |
| PDE1C | 0 | 1 | 0 | 0 | 1 |
| PEX2 | 0 | 1 | 0 | 0 | 1 |
| PHKA1 | 0 | 0 | 1 | 0 | 1 |
| PHKA2 | 0 | 0 | 1 | 0 | 1 |
| PHOX2B | 0 | 1 | 0 | 0 | 1 |
| PIEZO2 | 0 | 0 | 1 | 0 | 1 |
| PIGO | 0 | 0 | 1 | 0 | 1 |
| PIK3CA | 0 | 0 | 1 | 0 | 1 |
| PLA2G6 | 0 | 1 | 0 | 0 | 1 |
| PLEKHG5 | 0 | 1 | 0 | 0 | 1 |
| PNP | 0 | 1 | 0 | 0 | 1 |
| PNPLA1 | 0 | 1 | 0 | 0 | 1 |
| PNPT1 | 0 | 0 | 1 | 0 | 1 |
| POC1B, POC1B-DUSP6 | 0 | 0 | 1 | 0 | 1 |
| POGZ | 0 | 1 | 0 | 0 | 1 |
| POLA1 | 0 | 0 | 1 | 0 | 1 |
| POLG | 0 | 0 | 1 | 0 | 1 |
| POLR2F, SOX10 | 0 | 0 | 1 | 0 | 1 |
| POMGNT1, TSPAN1 | 0 | 1 | 0 | 0 | 1 |
| POMK | 0 | 0 | 1 | 0 | 1 |
| POU3F3 | 0 | 1 | 0 | 0 | 1 |
| PPT1 | 0 | 0 | 1 | 0 | 1 |
| PRKAR1B | 0 | 1 | 0 | 0 | 1 |
| PROC | 0 | 1 | 0 | 0 | 1 |
| PROKR2 | 0 | 0 | 1 | 0 | 1 |
| PROM1 | 0 | 1 | 0 | 0 | 1 |
| PSEN2 | 0 | 0 | 1 | 0 | 1 |
| PTEN | 0 | 1 | 0 | 0 | 1 |
| PTPN11 | 0 | 1 | 0 | 0 | 1 |
| PTPRA, VPS16 | 0 | 0 | 1 | 0 | 1 |
| RAB27A | 0 | 1 | 0 | 0 | 1 |
| RAI1 | 0 | 1 | 0 | 0 | 1 |
| RARS1 | 0 | 1 | 0 | 0 | 1 |
| RIPK4 | 0 | 0 | 1 | 0 | 1 |
| RIT1 | 0 | 0 | 1 | 0 | 1 |
| RMRP | 0 | 0 | 1 | 0 | 1 |
| RNF213 | 0 | 0 | 1 | 0 | 1 |
| RSPH3 | 0 | 1 | 0 | 0 | 1 |
| RTN4IP1 | 0 | 0 | 1 | 0 | 1 |
| RUBCN | 0 | 1 | 0 | 0 | 1 |
| RUNX2 | 0 | 0 | 1 | 0 | 1 |
| SASS6 | 0 | 1 | 0 | 0 | 1 |
| SBF2 | 0 | 1 | 0 | 0 | 1 |
| SCAF4 | 0 | 1 | 0 | 0 | 1 |
| SCN1B | 0 | 1 | 0 | 0 | 1 |
| SCN3A | 1 | 0 | 0 | 0 | 1 |
| SCN5A | 0 | 1 | 0 | 0 | 1 |
| SCN8A | 0 | 0 | 1 | 0 | 1 |
| SELENON | 0 | 0 | 1 | 0 | 1 |
| SENP7 | 0 | 1 | 0 | 0 | 1 |
| SEPSECS | 0 | 0 | 1 | 0 | 1 |
| SERPINC1 | 1 | 0 | 0 | 0 | 1 |
| SERPINF1 | 1 | 0 | 0 | 0 | 1 |
| SERPING1 | 1 | 0 | 0 | 0 | 1 |
| SETD5 | 0 | 1 | 0 | 0 | 1 |
| SGCB | 0 | 1 | 0 | 0 | 1 |
| SGPL1 | 1 | 0 | 0 | 0 | 1 |
| SHQ1 | 0 | 1 | 0 | 0 | 1 |
| SKI | 0 | 0 | 1 | 0 | 1 |
| SLC12A6 | 0 | 1 | 0 | 0 | 1 |
| SLC17A5 | 0 | 0 | 1 | 0 | 1 |
| SLC25A15 | 0 | 1 | 0 | 0 | 1 |
| SLC25A46 | 0 | 0 | 1 | 0 | 1 |
| SLC30A7 | 0 | 0 | 1 | 0 | 1 |
| SLC34A3 | 0 | 0 | 1 | 0 | 1 |
| SLC38A8 | 0 | 1 | 0 | 0 | 1 |
| SLC3A1 | 0 | 0 | 1 | 0 | 1 |
| SLC45A2 | 0 | 1 | 0 | 0 | 1 |
| SLC4A11 | 0 | 1 | 0 | 0 | 1 |
| SLC52A3 | 0 | 1 | 0 | 0 | 1 |
| SLC7A7 | 0 | 1 | 0 | 0 | 1 |
| SLC9A9 | 0 | 0 | 1 | 0 | 1 |
| SORCS1 | 0 | 1 | 0 | 0 | 1 |
| SOS1 | 0 | 0 | 1 | 0 | 1 |
| SOX11 | 0 | 0 | 1 | 0 | 1 |
| SPATA7 | 1 | 0 | 0 | 0 | 1 |
| SPEN | 0 | 0 | 1 | 0 | 1 |
| SPTAN1 | 0 | 1 | 0 | 0 | 1 |
| SPTB | 0 | 1 | 0 | 0 | 1 |
| SQSTM1 | 0 | 0 | 1 | 0 | 1 |
| SRGAP1 | 0 | 0 | 1 | 0 | 1 |
| STAG3 | 0 | 1 | 0 | 0 | 1 |
| STAR | 0 | 0 | 1 | 0 | 1 |
| STK11 | 1 | 0 | 0 | 0 | 1 |
| STXBP1 | 0 | 1 | 0 | 0 | 1 |
| SUPT16H | 1 | 0 | 0 | 0 | 1 |
| SYNJ1 | 0 | 1 | 0 | 0 | 1 |
| SYT2 | 0 | 1 | 0 | 0 | 1 |
| TANC2 | 0 | 0 | 1 | 0 | 1 |
| TBC1D24 | 0 | 0 | 1 | 0 | 1 |
| TBCEL-TECTA, TECTA | 0 | 0 | 1 | 0 | 1 |
| TBX1 | 0 | 1 | 0 | 0 | 1 |
| TBX18 | 0 | 0 | 1 | 0 | 1 |
| TBX3 | 0 | 0 | 1 | 0 | 1 |
| TBX6 | 0 | 1 | 0 | 0 | 1 |
| TCF20 | 0 | 1 | 0 | 0 | 1 |
| TGFBI | 0 | 1 | 0 | 0 | 1 |
| TGM1 | 0 | 1 | 0 | 0 | 1 |
| THBD | 0 | 1 | 0 | 0 | 1 |
| TLR2 | 0 | 0 | 1 | 0 | 1 |
| TLR5 | 0 | 1 | 0 | 0 | 1 |
| TMEM260 | 0 | 1 | 0 | 0 | 1 |
| TMEM63A | 0 | 0 | 1 | 0 | 1 |
| TMEM67 | 1 | 0 | 0 | 0 | 1 |
| TMPRSS3 | 0 | 1 | 0 | 0 | 1 |
| TNFRSF9 | 0 | 0 | 1 | 0 | 1 |
| TNNT1 | 0 | 1 | 0 | 0 | 1 |
| TNNT2 | 0 | 0 | 1 | 0 | 1 |
| TONSL | 0 | 1 | 0 | 0 | 1 |
| TP63 | 0 | 0 | 1 | 0 | 1 |
| TPM3 | 0 | 0 | 1 | 0 | 1 |
| TRAPPC11 | 0 | 0 | 1 | 0 | 1 |
| TRIM37 | 0 | 1 | 0 | 0 | 1 |
| TRIP13 | 0 | 1 | 0 | 0 | 1 |
| TRMT10C | 0 | 1 | 0 | 0 | 1 |
| TRPC6 | 0 | 0 | 1 | 0 | 1 |
| TRPM3 | 0 | 0 | 1 | 0 | 1 |
| TSC1 | 0 | 0 | 1 | 0 | 1 |
| TSHB | 0 | 0 | 1 | 0 | 1 |
| TSPOAP1 | 0 | 0 | 1 | 0 | 1 |
| TTC19 | 0 | 1 | 0 | 0 | 1 |
| TUBGCP6 | 0 | 0 | 1 | 0 | 1 |
| TWNK | 0 | 0 | 1 | 0 | 1 |
| TYMP | 1 | 0 | 0 | 0 | 1 |
| UMOD | 0 | 0 | 1 | 0 | 1 |
| UNC13D | 1 | 0 | 0 | 0 | 1 |
| UNC80 | 0 | 1 | 0 | 0 | 1 |
| UPB1 | 0 | 0 | 1 | 0 | 1 |
| UROS | 1 | 0 | 0 | 0 | 1 |
| UVSSA | 0 | 1 | 0 | 0 | 1 |
| VIM | 0 | 0 | 1 | 0 | 1 |
| VPS13A | 1 | 0 | 0 | 0 | 1 |
| WARS2 | 0 | 0 | 1 | 0 | 1 |
| WASF1 | 0 | 0 | 1 | 0 | 1 |
| WDR26 | 0 | 0 | 1 | 0 | 1 |
| WDR37 | 0 | 1 | 0 | 0 | 1 |
| WDR45 | 1 | 0 | 0 | 0 | 1 |
| WDR62 | 0 | 1 | 0 | 0 | 1 |
| WT1 | 0 | 1 | 0 | 0 | 1 |
| XPNPEP3 | 0 | 1 | 0 | 0 | 1 |
| XRCC1 | 0 | 1 | 0 | 0 | 1 |
| YY1 | 1 | 0 | 0 | 0 | 1 |
| ZBTB18 | 0 | 1 | 0 | 0 | 1 |
| ZNF148 | 0 | 0 | 1 | 0 | 1 |
| ZNF462 | 0 | 1 | 0 | 0 | 1 |
| ZYG11B | 0 | 1 | 0 | 0 | 1 |