Variants from Sharing Clinical Reports Project (SCRP)

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic	likely pathogenic	uncertain significance	likely benign	benign	not provided	total
963	46	813	223	312	1	2358

Gene and significance breakdown #

Total genes and gene combinations: 3

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Gene or gene combination	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	not provided	total
BRCA2	520	21	584	145	192	0	1462
BRCA1	372	24	197	69	107	1	770
BRCA1, LOC126862571	71	1	32	9	13	0	126

Condition and significance breakdown #

Total conditions: 2

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Condition	pathogenic	likely pathogenic	uncertain significance	likely benign	benign	not provided	total
Breast-ovarian cancer, familial, susceptibility to, 2	520	21	584	145	192	0	1462
Breast-ovarian cancer, familial, susceptibility to, 1	443	25	229	78	120	1	896

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