If a variant has more than one submission, it may be counted in more than one significance column. If this is the
case, the total number of variants will be less than the sum of the other cells.
Gene and significance breakdown #
Total genes and gene combinations: 1023
| Gene or gene combination |
pathogenic |
likely pathogenic |
uncertain significance |
likely benign |
benign |
total |
|
TTN
|
6
|
8
|
583
|
175
|
533
|
1305
|
|
SYNE1
|
33
|
28
|
651
|
167
|
199
|
1078
|
|
NOTCH3
|
181
|
21
|
214
|
78
|
102
|
596
|
|
PKD1
|
113
|
29
|
191
|
59
|
171
|
563
|
|
SACS
|
21
|
14
|
269
|
67
|
85
|
456
|
|
PLEC
|
0 |
0 |
190
|
87
|
145
|
422
|
|
CACNA1A
|
44
|
17
|
180
|
53
|
99
|
393
|
|
SETX
|
10
|
13
|
217
|
47
|
71
|
358
|
|
HSPG2
|
1
|
3
|
184
|
58
|
91
|
337
|
|
SPTBN2
|
1
|
2
|
168
|
64
|
99
|
334
|
|
GCK
|
81
|
51
|
117
|
5
|
18
|
272
|
|
ITPR1
|
0 |
2
|
113
|
36
|
96
|
247
|
|
DMD
|
123
|
10
|
50
|
7
|
58
|
246
|
|
TSC2
|
100
|
23
|
47
|
9
|
67
|
245
|
|
ATM
|
11
|
2
|
111
|
27
|
50
|
201
|
|
SYNE2
|
0 |
0 |
89
|
30
|
79
|
198
|
|
DYSF
|
30
|
9
|
74
|
25
|
40
|
178
|
|
CLCN1
|
48
|
20
|
83
|
13
|
13
|
177
|
|
POLG
|
17
|
8
|
97
|
32
|
17
|
171
|
|
GH-LCR, SCN4A
|
23
|
11
|
77
|
17
|
40
|
168
|
|
CACNA1H
|
0 |
0 |
43
|
23
|
97
|
163
|
|
TGM6
|
0 |
0 |
69
|
26
|
64
|
159
|
|
SPAST
|
93
|
18
|
40
|
1
|
5
|
156
|
|
HNF1A
|
48
|
14
|
50
|
9
|
33
|
154
|
|
ADGRV1
|
1
|
1
|
49
|
23
|
78
|
152
|
|
COQ8A
|
3
|
10
|
86
|
19
|
25
|
143
|
|
CASR
|
24
|
20
|
72
|
1
|
19
|
136
|
|
EEF2
|
1
|
0 |
38
|
26
|
57
|
122
|
|
GRM1
|
0 |
1
|
74
|
14
|
32
|
121
|
|
ATM, C11orf65
|
13
|
6
|
67
|
16
|
13
|
115
|
|
SPG11
|
20
|
5
|
51
|
9
|
29
|
114
|
|
NEB
|
1
|
1
|
32
|
17
|
62
|
113
|
|
TTBK2
|
2
|
0 |
51
|
22
|
32
|
107
|
|
CAPN3
|
44
|
11
|
28
|
7
|
16
|
106
|
|
MFN2
|
15
|
10
|
53
|
9
|
17
|
104
|
|
LAMA2
|
6
|
1
|
50
|
16
|
30
|
103
|
|
NF1
|
55
|
9
|
21
|
3
|
13
|
101
|
|
ZFYVE26
|
3
|
3
|
41
|
17
|
37
|
101
|
|
RYR1
|
6
|
6
|
51
|
9
|
28
|
100
|
|
GJB1
|
34
|
14
|
40
|
1
|
6
|
95
|
|
PRX
|
5
|
0 |
53
|
10
|
27
|
95
|
|
SH3TC2
|
6
|
2
|
49
|
20
|
18
|
95
|
|
ANO10
|
7
|
8
|
52
|
12
|
15
|
94
|
|
ASPM
|
2
|
1
|
32
|
7
|
52
|
94
|
|
OPA1
|
35
|
11
|
24
|
1
|
23
|
94
|
|
ABCC8
|
22
|
6
|
39
|
6
|
20
|
93
|
|
GJB2
|
44
|
7
|
27
|
5
|
7
|
90
|
|
HNF4A
|
15
|
4
|
36
|
8
|
26
|
89
|
|
PRKCG
|
4
|
5
|
56
|
7
|
16
|
88
|
|
KIF1A
|
0 |
0 |
42
|
12
|
33
|
87
|
|
COL4A4
|
10
|
17
|
14
|
6
|
39
|
86
|
|
AP5Z1
|
2
|
5
|
35
|
13
|
30
|
85
|
|
COL4A5
|
45
|
12
|
19
|
1
|
8
|
85
|
|
MRE11
|
2
|
4
|
47
|
15
|
16
|
84
|
|
COL1A1
|
26
|
6
|
13
|
2
|
36
|
83
|
|
KCND3
|
3
|
2
|
39
|
12
|
25
|
81
|
|
KMT2D
|
4
|
0 |
20
|
10
|
47
|
81
|
|
TRPV4
|
5
|
0 |
30
|
7
|
39
|
81
|
|
TSC1
|
46
|
6
|
4
|
1
|
23
|
80
|
|
CACNA1S
|
3
|
1
|
12
|
8
|
53
|
77
|
|
SCN4A
|
3
|
4
|
24
|
5
|
41
|
77
|
|
AFG3L2
|
5
|
2
|
48
|
6
|
12
|
73
|
|
VPS13B
|
3
|
1
|
31
|
15
|
22
|
72
|
|
SIL1
|
1
|
0 |
42
|
10
|
17
|
70
|
|
DYNC1H1
|
0 |
0 |
12
|
10
|
47
|
69
|
|
VPS13A
|
2
|
0 |
29
|
9
|
29
|
69
|
|
ALS2
|
0 |
0 |
38
|
7
|
23
|
68
|
|
COL4A1
|
3
|
4
|
16
|
3
|
42
|
68
|
|
COL4A3, MFF-DT
|
15
|
11
|
10
|
6
|
26
|
68
|
|
MPZ
|
26
|
16
|
19
|
2
|
5
|
68
|
|
CYP21A2, LOC106780800
|
22
|
10
|
17
|
8
|
10
|
67
|
|
KCNC3
|
2
|
0 |
24
|
13
|
28
|
67
|
|
SLC1A3
|
0 |
0 |
36
|
6
|
25
|
67
|
|
POMT1
|
1
|
3
|
30
|
11
|
21
|
66
|
|
SPG7
|
18
|
4
|
28
|
4
|
12
|
66
|
|
DNM2
|
2
|
1
|
30
|
6
|
26
|
65
|
|
FIG4
|
6
|
4
|
35
|
8
|
12
|
65
|
|
ANO5
|
10
|
4
|
33
|
7
|
10
|
64
|
|
LMNA
|
9
|
6
|
30
|
6
|
12
|
63
|
|
SHOX
|
5
|
1
|
34
|
5
|
17
|
62
|
|
COL6A3
|
0 |
2
|
9
|
3
|
47
|
61
|
|
LOC102724058, SCN1A
|
26
|
6
|
17
|
3
|
9
|
61
|
|
SCN1A
|
23
|
6
|
16
|
5
|
12
|
61
|
|
ANKRD11
|
0 |
0 |
10
|
12
|
38
|
60
|
|
RELN
|
0 |
0 |
17
|
10
|
33
|
60
|
|
GRN
|
17
|
2
|
14
|
3
|
23
|
59
|
|
PSEN1
|
18
|
15
|
17
|
4
|
5
|
59
|
|
FLVCR1
|
1
|
3
|
41
|
7
|
6
|
58
|
|
SZT2
|
0 |
0 |
24
|
8
|
26
|
58
|
|
PKD2
|
27
|
3
|
14
|
2
|
10
|
56
|
|
SLC12A3
|
20
|
5
|
11
|
4
|
16
|
56
|
|
PNPLA6
|
2
|
1
|
26
|
9
|
17
|
55
|
|
COL1A2
|
17
|
1
|
9
|
4
|
23
|
54
|
|
MTPAP
|
0 |
0 |
35
|
10
|
9
|
54
|
|
FLNC
|
0 |
1
|
8
|
2
|
40
|
51
|
|
ATP1A2
|
5
|
3
|
22
|
1
|
19
|
50
|
|
TDP1
|
0 |
1
|
35
|
4
|
10
|
50
|
|
POLG, POLGARF
|
2
|
2
|
34
|
6
|
5
|
49
|
|
CACNB4
|
0 |
0 |
30
|
5
|
13
|
48
|
|
KCNT1
|
0 |
1
|
13
|
6
|
28
|
48
|
|
GARS1
|
2
|
0 |
15
|
6
|
24
|
47
|
|
TTR
|
20
|
6
|
12
|
2
|
7
|
47
|
|
SBF2
|
4
|
0 |
26
|
8
|
8
|
46
|
|
SCN2A
|
4
|
3
|
13
|
7
|
19
|
46
|
|
SYT14
|
0 |
0 |
35
|
5
|
6
|
46
|
|
SCN5A
|
0 |
2
|
9
|
10
|
24
|
45
|
|
USH2A
|
1
|
0 |
6
|
6
|
32
|
45
|
|
BRAT1
|
0 |
0 |
17
|
6
|
21
|
44
|
|
LRRK2
|
3
|
0 |
10
|
4
|
27
|
44
|
|
SPTAN1
|
1
|
0 |
8
|
11
|
24
|
44
|
|
ATP2A1
|
2
|
4
|
21
|
4
|
12
|
43
|
|
WDR62
|
0 |
0 |
9
|
5
|
28
|
42
|
|
APP
|
4
|
3
|
16
|
2
|
17
|
41
|
|
GLDC
|
1
|
2
|
14
|
6
|
19
|
41
|
|
NEFL
|
2
|
3
|
25
|
3
|
8
|
41
|
|
OTOG
|
0 |
2
|
5
|
5
|
29
|
41
|
|
POMT2
|
0 |
1
|
19
|
5
|
16
|
41
|
|
CYP11B1, LOC106799833
|
6
|
2
|
16
|
3
|
13
|
40
|
|
HNF1B
|
6
|
1
|
19
|
6
|
8
|
40
|
|
SMN1
|
14
|
9
|
13
|
1
|
3
|
40
|
|
APTX
|
2
|
4
|
19
|
6
|
8
|
39
|
|
FLNA
|
2
|
1
|
7
|
4
|
25
|
39
|
|
NPHS1
|
10
|
1
|
10
|
4
|
14
|
39
|
|
SCN1A, SCN9A
|
0 |
0 |
16
|
8
|
15
|
39
|
|
ATP13A2
|
0 |
1
|
8
|
2
|
27
|
38
|
|
HCN4
|
0 |
0 |
9
|
8
|
21
|
38
|
|
KCNH2
|
0 |
0 |
16
|
6
|
16
|
38
|
|
PMP22
|
9
|
6
|
18
|
1
|
4
|
38
|
|
CNTNAP2
|
0 |
0 |
14
|
6
|
17
|
37
|
|
DAG1
|
0 |
0 |
22
|
5
|
10
|
37
|
|
DEPDC5
|
2
|
0 |
15
|
1
|
19
|
37
|
|
FGD4
|
1
|
1
|
15
|
7
|
13
|
37
|
|
HSPB1
|
8
|
3
|
13
|
4
|
9
|
37
|
|
KCNA1
|
3
|
2
|
16
|
5
|
11
|
37
|
|
PDX1
|
2
|
1
|
15
|
6
|
13
|
37
|
|
DCTN1
|
1
|
1
|
10
|
5
|
19
|
36
|
|
DES
|
3
|
4
|
14
|
3
|
12
|
36
|
|
FKRP
|
3
|
2
|
16
|
4
|
10
|
35
|
|
TRAPPC11
|
0 |
0 |
18
|
5
|
12
|
35
|
|
TTPA
|
6
|
1
|
17
|
6
|
5
|
35
|
|
CDH23
|
1
|
0 |
9
|
3
|
21
|
34
|
|
CLCNKB, LOC106501713
|
2
|
1
|
8
|
3
|
20
|
34
|
|
PDYN
|
0 |
0 |
16
|
5
|
13
|
34
|
|
CHD2
|
1
|
0 |
6
|
5
|
21
|
33
|
|
GFAP
|
2
|
2
|
12
|
3
|
14
|
33
|
|
AGRN
|
0 |
0 |
4
|
3
|
25
|
32
|
|
RAI1
|
0 |
1
|
9
|
4
|
18
|
32
|
|
SMCHD1
|
0 |
1
|
10
|
5
|
16
|
32
|
|
CASD1, SGCE
|
16
|
2
|
3
|
0 |
10
|
31
|
|
FUS
|
4
|
1
|
9
|
3
|
14
|
31
|
|
KANSL1
|
0 |
0 |
2
|
5
|
24
|
31
|
|
RTN2
|
0 |
1
|
15
|
2
|
13
|
31
|
|
SOD1
|
13
|
2
|
11
|
0 |
5
|
31
|
|
SQSTM1
|
0 |
0 |
11
|
4
|
16
|
31
|
|
SYNJ1
|
0 |
1
|
8
|
9
|
13
|
31
|
|
WASHC5
|
1
|
1
|
10
|
3
|
16
|
31
|
|
INF2
|
1
|
1
|
3
|
2
|
23
|
30
|
|
KCNJ11
|
4
|
6
|
9
|
3
|
8
|
30
|
|
KIF5A
|
4
|
2
|
10
|
5
|
9
|
30
|
|
LOC101928008, SBF2
|
0 |
0 |
21
|
2
|
7
|
30
|
|
OTOF
|
0 |
0 |
6
|
1
|
23
|
30
|
|
SGCA
|
5
|
2
|
11
|
6
|
6
|
30
|
|
WWOX
|
0 |
0 |
7
|
3
|
20
|
30
|
|
COL6A2
|
2
|
1
|
3
|
2
|
21
|
29
|
|
KCNMA1
|
0 |
0 |
7
|
6
|
16
|
29
|
|
MCPH1
|
0 |
1
|
6
|
1
|
21
|
29
|
|
MYO7A
|
1
|
2
|
7
|
5
|
14
|
29
|
|
PSEN2
|
1
|
2
|
6
|
5
|
15
|
29
|
|
SCNN1B
|
7
|
0 |
6
|
4
|
12
|
29
|
|
ABCD1, PLXNB3
|
9
|
4
|
11
|
0 |
4
|
28
|
|
ADGRG1
|
0 |
0 |
10
|
7
|
11
|
28
|
|
FGF14
|
1
|
0 |
11
|
6
|
10
|
28
|
|
MYO15A
|
1
|
1
|
12
|
6
|
8
|
28
|
|
NIPBL
|
0 |
0 |
11
|
4
|
13
|
28
|
|
SGCG
|
4
|
0 |
13
|
4
|
7
|
28
|
|
CHRNA4
|
0 |
0 |
7
|
1
|
19
|
27
|
|
COL6A1
|
1
|
0 |
7
|
3
|
16
|
27
|
|
CYP7B1
|
5
|
0 |
16
|
2
|
4
|
27
|
|
FXN
|
5
|
3
|
13
|
1
|
5
|
27
|
|
LOC101927055, TTN
|
0 |
0 |
11
|
3
|
13
|
27
|
|
NDRG1
|
0 |
1
|
16
|
5
|
5
|
27
|
|
ARFGEF2
|
0 |
0 |
15
|
2
|
9
|
26
|
|
KCNQ2
|
2
|
4
|
6
|
3
|
11
|
26
|
|
MT-CO1
|
0 |
0 |
2
|
3
|
21
|
26
|
|
NRXN1
|
0 |
0 |
6
|
6
|
14
|
26
|
|
PCDH19
|
8
|
2
|
5
|
5
|
6
|
26
|
|
BSCL2, HNRNPUL2-BSCL2
|
3
|
0 |
11
|
7
|
4
|
25
|
|
EFHC1
|
0 |
0 |
7
|
4
|
14
|
25
|
|
FGFR3
|
0 |
0 |
2
|
4
|
19
|
25
|
|
HTRA1
|
0 |
0 |
13
|
2
|
10
|
25
|
|
IGHMBP2
|
2
|
0 |
4
|
4
|
15
|
25
|
|
MECP2
|
9
|
0 |
3
|
1
|
12
|
25
|
|
NEB, RIF1
|
1
|
0 |
8
|
3
|
13
|
25
|
|
POMGNT1, TSPAN1
|
1
|
1
|
9
|
8
|
6
|
25
|
|
RET
|
9
|
0 |
3
|
1
|
12
|
25
|
|
SCN3A
|
0 |
1
|
8
|
2
|
14
|
25
|
|
ALG13
|
0 |
0 |
6
|
3
|
15
|
24
|
|
ALMS1
|
0 |
0 |
1
|
2
|
21
|
24
|
|
ATL1
|
4
|
3
|
7
|
2
|
8
|
24
|
|
CHD7
|
4
|
0 |
4
|
2
|
14
|
24
|
|
DPYD
|
1
|
0 |
10
|
2
|
11
|
24
|
|
FXN, LOC130001862
|
2
|
1
|
11
|
2
|
8
|
24
|
|
L1CAM
|
0 |
0 |
10
|
2
|
12
|
24
|
|
MAGI2
|
0 |
0 |
9
|
3
|
12
|
24
|
|
MAPT
|
4
|
3
|
4
|
1
|
12
|
24
|
|
MYH14
|
0 |
0 |
3
|
2
|
19
|
24
|
|
MYOT, PKD2L2-DT
|
3
|
1
|
5
|
1
|
14
|
24
|
|
PCDH15
|
0 |
0 |
4
|
2
|
18
|
24
|
|
SETD2
|
0 |
0 |
7
|
3
|
14
|
24
|
|
SLC12A1
|
0 |
3
|
8
|
4
|
9
|
24
|
|
WNK1
|
0 |
0 |
3
|
0 |
21
|
24
|
|
GRIN2B
|
0 |
0 |
1
|
4
|
18
|
23
|
|
LOC126862019, TDP1
|
0 |
1
|
14
|
4
|
4
|
23
|
|
LOXHD1
|
0 |
0 |
5
|
3
|
15
|
23
|
|
MTMR2
|
0 |
0 |
11
|
3
|
9
|
23
|
|
PRKN
|
6
|
3
|
4
|
2
|
8
|
23
|
|
ACTN4
|
1
|
0 |
1
|
2
|
18
|
22
|
|
AFG2A
|
0 |
3
|
6
|
3
|
10
|
22
|
|
AIRE
|
5
|
1
|
3
|
3
|
10
|
22
|
|
ATP1A3
|
0 |
0 |
2
|
3
|
17
|
22
|
|
COL18A1
|
0 |
1
|
9
|
2
|
10
|
22
|
|
DOCK7
|
0 |
0 |
4
|
4
|
14
|
22
|
|
EGR2
|
3
|
0 |
12
|
0 |
7
|
22
|
|
HSPG2, LDLRAD2
|
0 |
0 |
8
|
5
|
9
|
22
|
|
LOC107652445, SHOX
|
3
|
1
|
11
|
3
|
4
|
22
|
|
PINK1
|
1
|
0 |
12
|
2
|
7
|
22
|
|
SLC2A1
|
2
|
0 |
2
|
3
|
15
|
22
|
|
TPP1
|
1
|
0 |
7
|
3
|
11
|
22
|
|
FKTN
|
1
|
1
|
8
|
4
|
7
|
21
|
|
GDAP1
|
6
|
1
|
9
|
4
|
1
|
21
|
|
GRIN2A
|
0 |
0 |
8
|
1
|
12
|
21
|
|
PIGN
|
0 |
1
|
11
|
2
|
7
|
21
|
|
PLCE1
|
0 |
0 |
10
|
2
|
9
|
21
|
|
PRICKLE2
|
0 |
0 |
9
|
4
|
8
|
21
|
|
REEP1
|
6
|
0 |
11
|
0 |
4
|
21
|
|
RIPOR2
|
0 |
0 |
2
|
2
|
17
|
21
|
|
SETBP1
|
0 |
0 |
4
|
1
|
16
|
21
|
|
SLC19A3
|
0 |
0 |
8
|
3
|
10
|
21
|
|
TNC
|
0 |
0 |
1
|
3
|
17
|
21
|
|
TSEN54
|
0 |
0 |
5
|
2
|
14
|
21
|
|
CCDC88C
|
0 |
0 |
7
|
12
|
1
|
20
|
|
GCH1
|
4
|
5
|
10
|
0 |
1
|
20
|
|
KRIT1
|
9
|
5
|
3
|
1
|
2
|
20
|
|
NPHS2
|
8
|
2
|
2
|
2
|
6
|
20
|
|
PHEX
|
12
|
0 |
4
|
0 |
4
|
20
|
|
PLCB1
|
0 |
0 |
3
|
4
|
13
|
20
|
|
PRICKLE1
|
0 |
0 |
10
|
1
|
9
|
20
|
|
RAB3GAP1
|
0 |
0 |
7
|
2
|
11
|
20
|
|
SCN8A
|
2
|
0 |
6
|
0 |
12
|
20
|
|
SIK1
|
0 |
0 |
3
|
1
|
16
|
20
|
|
VCP
|
2
|
1
|
6
|
0 |
11
|
20
|
|
ALPL
|
0 |
4
|
5
|
1
|
9
|
19
|
|
ASAH1
|
0 |
0 |
9
|
5
|
5
|
19
|
|
ATRX
|
0 |
0 |
5
|
4
|
10
|
19
|
|
CYP27A1
|
0 |
1
|
9
|
3
|
6
|
19
|
|
LARGE1
|
0 |
0 |
6
|
4
|
9
|
19
|
|
LOC126859837, SYNE1
|
0 |
3
|
10
|
6
|
0 |
19
|
|
MT-ND1
|
0 |
0 |
0 |
5
|
14
|
19
|
|
PTPRQ
|
0 |
0 |
3
|
0 |
16
|
19
|
|
SLC6A8
|
1
|
1
|
6
|
0 |
11
|
19
|
|
TBC1D24
|
0 |
1
|
5
|
6
|
7
|
19
|
|
TBX1
|
0 |
0 |
7
|
2
|
10
|
19
|
|
TH
|
0 |
0 |
5
|
2
|
12
|
19
|
|
TRPC6
|
2
|
0 |
5
|
0 |
12
|
19
|
|
CAV3, OXTR
|
1
|
1
|
7
|
0 |
9
|
18
|
|
FA2H
|
1
|
0 |
7
|
3
|
7
|
18
|
|
LMNB2
|
0 |
0 |
8
|
4
|
6
|
18
|
|
MEN1
|
11
|
1
|
1
|
1
|
4
|
18
|
|
MVP-DT, PRRT2
|
5
|
0 |
5
|
1
|
7
|
18
|
|
NTRK1
|
0 |
0 |
3
|
2
|
13
|
18
|
|
SELENON
|
2
|
1
|
5
|
2
|
8
|
18
|
|
SLC6A1
|
1
|
0 |
2
|
4
|
11
|
18
|
|
TARDBP
|
3
|
0 |
6
|
2
|
7
|
18
|
|
ABAT
|
0 |
0 |
2
|
2
|
13
|
17
|
|
ASTN2, TRIM32
|
0 |
0 |
12
|
3
|
2
|
17
|
|
CACNA2D1
|
0 |
0 |
4
|
3
|
10
|
17
|
|
CCDC78
|
0 |
0 |
6
|
7
|
4
|
17
|
|
CHRNB2
|
0 |
0 |
7
|
1
|
9
|
17
|
|
CPAP
|
0 |
0 |
4
|
1
|
12
|
17
|
|
OPTN
|
0 |
2
|
8
|
1
|
6
|
17
|
|
PIGO
|
0 |
0 |
6
|
2
|
9
|
17
|
|
PNKP
|
1
|
1
|
2
|
6
|
7
|
17
|
|
TWNK
|
2
|
0 |
12
|
0 |
3
|
17
|
|
WFS1
|
2
|
0 |
3
|
5
|
7
|
17
|
|
YARS1
|
1
|
0 |
10
|
3
|
3
|
17
|
|
CTSF
|
0 |
0 |
3
|
2
|
11
|
16
|
|
GABRG2
|
1
|
0 |
4
|
1
|
10
|
16
|
|
HSPB8
|
1
|
0 |
6
|
3
|
6
|
16
|
|
LAMB2
|
0 |
1
|
4
|
4
|
7
|
16
|
|
LBR
|
0 |
0 |
4
|
1
|
11
|
16
|
|
LOC126806425, TTN
|
0 |
0 |
6
|
2
|
8
|
16
|
|
MBD5
|
0 |
0 |
4
|
6
|
6
|
16
|
|
STIL
|
0 |
0 |
6
|
1
|
9
|
16
|
|
COL2A1
|
0 |
0 |
1
|
3
|
11
|
15
|
|
COL9A2
|
0 |
0 |
1
|
0 |
14
|
15
|
|
DNAJB6
|
1
|
0 |
5
|
3
|
6
|
15
|
|
DOK7
|
3
|
0 |
3
|
3
|
6
|
15
|
|
ITPR1, LOC126806590
|
0 |
1
|
5
|
2
|
7
|
15
|
|
LEPR
|
0 |
1
|
3
|
1
|
10
|
15
|
|
LOC126806422, TTN
|
0 |
0 |
5
|
1
|
9
|
15
|
|
MC4R
|
4
|
1
|
6
|
1
|
3
|
15
|
|
MYBPC3
|
1
|
1
|
5
|
1
|
7
|
15
|
|
MYH7
|
0 |
0 |
1
|
1
|
13
|
15
|
|
SLC33A1
|
0 |
0 |
5
|
2
|
8
|
15
|
|
SLC4A10
|
0 |
1
|
8
|
2
|
4
|
15
|
|
TCOF1
|
0 |
0 |
1
|
1
|
13
|
15
|
|
ATP6V0A2
|
1
|
0 |
6
|
3
|
4
|
14
|
|
AVPR2
|
5
|
2
|
2
|
0 |
5
|
14
|
|
CPT2
|
1
|
0 |
8
|
1
|
4
|
14
|
|
DEAF1
|
0 |
0 |
5
|
2
|
7
|
14
|
|
EEF2, LOC130063169
|
0 |
0 |
1
|
3
|
10
|
14
|
|
HSPD1
|
0 |
0 |
5
|
1
|
8
|
14
|
|
KCNQ3
|
0 |
0 |
5
|
3
|
6
|
14
|
|
L2HGDH
|
0 |
0 |
3
|
3
|
8
|
14
|
|
LOC105369149, SBF2
|
0 |
0 |
7
|
3
|
4
|
14
|
|
LOC126806424, TTN
|
0 |
0 |
9
|
2
|
3
|
14
|
|
LOC126806430, TTN
|
0 |
0 |
2
|
4
|
8
|
14
|
|
ROGDI
|
0 |
0 |
2
|
4
|
8
|
14
|
|
SCNN1G
|
0 |
1
|
2
|
0 |
11
|
14
|
|
SGCD
|
0 |
0 |
2
|
3
|
9
|
14
|
|
TAPBPL, VAMP1
|
3
|
1
|
8
|
0 |
2
|
14
|
|
ZEB2
|
0 |
0 |
5
|
1
|
8
|
14
|
|
BDP1
|
0 |
0 |
5
|
1
|
7
|
13
|
|
CCM2
|
7
|
1
|
2
|
0 |
4
|
13
|
|
CEMIP
|
0 |
0 |
4
|
3
|
6
|
13
|
|
CLCNKA, LOC106501712
|
0 |
0 |
3
|
2
|
8
|
13
|
|
FGFR1
|
2
|
1
|
3
|
0 |
7
|
13
|
|
GABRD
|
0 |
0 |
6
|
3
|
4
|
13
|
|
HNF1B, LOC126862549
|
3
|
1
|
6
|
0 |
3
|
13
|
|
KIFBP
|
0 |
0 |
5
|
0 |
8
|
13
|
|
LOC126806428, TTN
|
0 |
0 |
3
|
3
|
7
|
13
|
|
LOC129992813, PKD2
|
5
|
0 |
2
|
1
|
5
|
13
|
|
MEGF10
|
0 |
0 |
4
|
2
|
7
|
13
|
|
MYH9
|
0 |
0 |
2
|
1
|
10
|
13
|
|
NF2
|
7
|
0 |
1
|
2
|
3
|
13
|
|
PDZD7
|
0 |
0 |
2
|
4
|
7
|
13
|
|
PLA2G6
|
0 |
0 |
7
|
3
|
3
|
13
|
|
QARS1
|
0 |
0 |
6
|
2
|
5
|
13
|
|
SIX3
|
1
|
0 |
2
|
1
|
9
|
13
|
|
SMC3
|
0 |
0 |
0 |
3
|
10
|
13
|
|
SPART
|
0 |
0 |
6
|
4
|
3
|
13
|
|
SYNGAP1
|
1
|
0 |
2
|
0 |
10
|
13
|
|
TBCEL-TECTA, TECTA
|
1
|
0 |
3
|
3
|
6
|
13
|
|
TMEM43
|
0 |
0 |
6
|
2
|
5
|
13
|
|
UMOD
|
4
|
1
|
4
|
0 |
4
|
13
|
|
WT1
|
7
|
0 |
2
|
0 |
4
|
13
|
|
ACTG1
|
1
|
0 |
1
|
0 |
10
|
12
|
|
CACNA1D
|
1
|
0 |
4
|
0 |
7
|
12
|
|
CHMP2B
|
0 |
1
|
6
|
1
|
4
|
12
|
|
COL18A1, SLC19A1
|
0 |
0 |
2
|
4
|
6
|
12
|
|
COL9A3
|
0 |
0 |
0 |
1
|
11
|
12
|
|
EEF1A2
|
0 |
0 |
0 |
0 |
12
|
12
|
|
FHL1
|
2
|
0 |
3
|
1
|
6
|
12
|
|
GRIN1
|
0 |
0 |
2
|
1
|
9
|
12
|
|
KLHL40
|
0 |
0 |
4
|
1
|
7
|
12
|
|
LARS2
|
0 |
0 |
1
|
2
|
9
|
12
|
|
LDB3
|
0 |
0 |
1
|
1
|
10
|
12
|
|
LDLR
|
5
|
2
|
2
|
1
|
2
|
12
|
|
LOC126806427, TTN
|
0 |
0 |
3
|
0 |
9
|
12
|
|
LOC126859838, SYNE1
|
1
|
0 |
8
|
3
|
0 |
12
|
|
LRP5
|
0 |
0 |
1
|
1
|
10
|
12
|
|
MT-RNR1
|
0 |
0 |
3
|
1
|
8
|
12
|
|
NEXMIF
|
0 |
0 |
2
|
3
|
7
|
12
|
|
NLRP3
|
0 |
1
|
2
|
1
|
8
|
12
|
|
PHGDH
|
0 |
1
|
1
|
1
|
9
|
12
|
|
SCARB2
|
0 |
0 |
5
|
2
|
5
|
12
|
|
SGCB
|
2
|
0 |
6
|
3
|
1
|
12
|
|
STXBP1
|
1
|
0 |
1
|
1
|
9
|
12
|
|
TJP2
|
0 |
0 |
2
|
0 |
10
|
12
|
|
ABCD1
|
0 |
2
|
6
|
0 |
3
|
11
|
|
ADSL
|
2
|
0 |
3
|
1
|
5
|
11
|
|
BCKDK
|
0 |
0 |
6
|
2
|
3
|
11
|
|
CAVIN1
|
0 |
0 |
2
|
5
|
4
|
11
|
|
CHSY1
|
0 |
0 |
2
|
1
|
8
|
11
|
|
CLN5
|
0 |
0 |
6
|
1
|
4
|
11
|
|
CLN6
|
0 |
0 |
3
|
2
|
6
|
11
|
|
DMP1, DSPP
|
0 |
0 |
0 |
0 |
11
|
11
|
|
EPM2A
|
0 |
0 |
8
|
0 |
3
|
11
|
|
ESR1, SYNE1
|
0 |
0 |
8
|
0 |
3
|
11
|
|
LITAF
|
2
|
0 |
2
|
1
|
6
|
11
|
|
LOC126806420, TTN
|
0 |
0 |
5
|
0 |
6
|
11
|
|
LOC126806423, TTN
|
1
|
0 |
6
|
1
|
3
|
11
|
|
MT-CO2
|
0 |
0 |
2
|
0 |
9
|
11
|
|
MUSK
|
0 |
0 |
5
|
1
|
5
|
11
|
|
OTOGL
|
0 |
0 |
3
|
0 |
8
|
11
|
|
PEX6
|
0 |
1
|
2
|
0 |
8
|
11
|
|
SLC25A22
|
0 |
0 |
4
|
4
|
3
|
11
|
|
SLC4A11
|
0 |
0 |
2
|
2
|
7
|
11
|
|
SLC9A6
|
0 |
0 |
4
|
2
|
5
|
11
|
|
STRC
|
0 |
1
|
4
|
3
|
3
|
11
|
|
SYN1
|
0 |
0 |
4
|
1
|
6
|
11
|
|
TCAP
|
1
|
1
|
5
|
2
|
2
|
11
|
|
TCF4
|
0 |
0 |
2
|
1
|
8
|
11
|
|
TUBA1A
|
0 |
0 |
1
|
2
|
8
|
11
|
|
WHRN
|
0 |
0 |
2
|
4
|
5
|
11
|
|
ATRIP, ATRIP-TREX1, TREX1
|
1
|
0 |
6
|
1
|
2
|
10
|
|
AXDND1, NPHS2
|
3
|
3
|
2
|
1
|
1
|
10
|
|
C17orf107, CHRNE
|
0 |
4
|
4
|
0 |
2
|
10
|
|
CHRNA2
|
0 |
0 |
5
|
2
|
3
|
10
|
|
CLN8
|
0 |
0 |
4
|
1
|
5
|
10
|
|
COL11A1
|
1
|
0 |
2
|
0 |
7
|
10
|
|
COL11A2
|
0 |
1
|
2
|
2
|
5
|
10
|
|
COL9A1
|
0 |
1
|
2
|
2
|
5
|
10
|
|
CRPPA
|
0 |
0 |
4
|
3
|
3
|
10
|
|
CYP11B1
|
1
|
1
|
3
|
1
|
4
|
10
|
|
DYRK1A
|
0 |
0 |
4
|
0 |
6
|
10
|
|
FLVCR1, LOC129932486
|
0 |
1
|
7
|
1
|
1
|
10
|
|
GNAO1
|
0 |
0 |
1
|
1
|
8
|
10
|
|
HCN1
|
0 |
0 |
2
|
0 |
8
|
10
|
|
HSD17B4
|
0 |
2
|
2
|
1
|
5
|
10
|
|
HSPG2, LOC126805655
|
0 |
0 |
7
|
2
|
1
|
10
|
|
IQSEC2
|
0 |
1
|
1
|
1
|
7
|
10
|
|
KCNJ10
|
0 |
0 |
8
|
2
|
0 |
10
|
|
LHCGR, STON1-GTF2A1L
|
3
|
0 |
2
|
0 |
5
|
10
|
|
LOC126806421, TTN
|
0 |
0 |
5
|
1
|
4
|
10
|
|
LOC130059818, SPG7
|
0 |
1
|
7
|
0 |
2
|
10
|
|
MYO3A
|
0 |
0 |
3
|
2
|
5
|
10
|
|
OFD1
|
0 |
0 |
4
|
1
|
5
|
10
|
|
OPHN1
|
0 |
0 |
4
|
1
|
5
|
10
|
|
RNASEH2B
|
1
|
1
|
1
|
0 |
7
|
10
|
|
SCN1B
|
1
|
0 |
4
|
2
|
3
|
10
|
|
SEPTIN9
|
1
|
0 |
1
|
2
|
6
|
10
|
|
SERPINI1
|
0 |
0 |
4
|
2
|
4
|
10
|
|
SNHG14, UBE3A
|
0 |
0 |
3
|
1
|
6
|
10
|
|
SUCLA2
|
0 |
1
|
3
|
0 |
6
|
10
|
|
TMC1
|
2
|
1
|
3
|
1
|
3
|
10
|
|
ALDH7A1
|
0 |
1
|
1
|
4
|
3
|
9
|
|
ARSA
|
4
|
0 |
1
|
0 |
4
|
9
|
|
CACNA1A, LOC126862864
|
0 |
0 |
7
|
1
|
1
|
9
|
|
CHRNA1
|
0 |
1
|
2
|
3
|
3
|
9
|
|
CLN3
|
1
|
0 |
1
|
4
|
3
|
9
|
|
FOXG1
|
1
|
0 |
4
|
3
|
1
|
9
|
|
GNE
|
2
|
0 |
3
|
0 |
4
|
9
|
|
HSD11B2
|
0 |
0 |
3
|
0 |
6
|
9
|
|
ITGA7
|
0 |
0 |
1
|
1
|
7
|
9
|
|
KCNC1
|
1
|
0 |
4
|
0 |
4
|
9
|
|
LOC110121269, SCN5A
|
0 |
1
|
2
|
0 |
6
|
9
|
|
LOC126806429, TTN
|
0 |
0 |
2
|
0 |
7
|
9
|
|
LOC126806431, TTN
|
0 |
0 |
5
|
0 |
4
|
9
|
|
LOC126859836, SYNE1
|
1
|
0 |
6
|
1
|
1
|
9
|
|
LOC129997480, SYNE1
|
0 |
0 |
6
|
2
|
1
|
9
|
|
MYO6
|
0 |
0 |
3
|
1
|
5
|
9
|
|
NR0B1
|
6
|
1
|
0 |
0 |
2
|
9
|
|
PARK7
|
1
|
0 |
3
|
2
|
3
|
9
|
|
PEX1
|
2
|
0 |
3
|
1
|
3
|
9
|
|
SCN9A
|
0 |
2
|
4
|
1
|
2
|
9
|
|
SLC26A4
|
0 |
0 |
4
|
1
|
4
|
9
|
|
THAP1
|
0 |
2
|
2
|
2
|
3
|
9
|
|
TRIOBP
|
0 |
0 |
3
|
4
|
2
|
9
|
|
UBQLN2
|
0 |
0 |
6
|
1
|
2
|
9
|
|
ANG, EGILA, RNASE4
|
0 |
0 |
3
|
1
|
4
|
8
|
|
ATP2A2
|
0 |
0 |
1
|
0 |
7
|
8
|
|
BAG3
|
0 |
0 |
0 |
1
|
7
|
8
|
|
CHAT
|
0 |
0 |
3
|
0 |
5
|
8
|
|
CHRND
|
0 |
0 |
3
|
1
|
4
|
8
|
|
CSTB
|
5
|
0 |
2
|
0 |
1
|
8
|
|
CTSD
|
0 |
0 |
1
|
1
|
6
|
8
|
|
DHCR7
|
1
|
1
|
0 |
0 |
6
|
8
|
|
EMD
|
2
|
1
|
1
|
2
|
2
|
8
|
|
FANCI, POLG
|
0 |
0 |
5
|
1
|
2
|
8
|
|
GABRA1
|
0 |
1
|
3
|
1
|
3
|
8
|
|
GABRB3
|
0 |
0 |
4
|
0 |
4
|
8
|
|
GAMT
|
0 |
0 |
5
|
2
|
1
|
8
|
|
GJB3
|
0 |
0 |
1
|
2
|
5
|
8
|
|
GLUD1
|
1
|
0 |
1
|
0 |
6
|
8
|
|
GPSM2
|
0 |
0 |
2
|
0 |
6
|
8
|
|
GRIA3
|
0 |
0 |
2
|
3
|
3
|
8
|
|
HNRNPU
|
0 |
0 |
1
|
1
|
6
|
8
|
|
KBTBD13
|
0 |
0 |
2
|
1
|
5
|
8
|
|
KCNB1
|
0 |
0 |
0 |
1
|
7
|
8
|
|
KCNJ1
|
2
|
0 |
0 |
2
|
4
|
8
|
|
LOC126807238, TRAPPC11
|
0 |
0 |
4
|
2
|
2
|
8
|
|
MCM2
|
0 |
0 |
3
|
2
|
3
|
8
|
|
MYH2, MYHAS
|
0 |
1
|
4
|
2
|
1
|
8
|
|
NHLRC1
|
1
|
0 |
5
|
0 |
2
|
8
|
|
NIPA1
|
1
|
0 |
4
|
1
|
2
|
8
|
|
PHEX, PTCHD1
|
5
|
0 |
2
|
0 |
1
|
8
|
|
PNPO
|
1
|
1
|
2
|
2
|
2
|
8
|
|
RAB7A
|
1
|
0 |
2
|
1
|
4
|
8
|
|
RAPSN
|
2
|
1
|
1
|
1
|
3
|
8
|
|
SALL1
|
0 |
0 |
1
|
0 |
7
|
8
|
|
SDHB
|
2
|
2
|
2
|
0 |
2
|
8
|
|
SHH
|
0 |
0 |
1
|
1
|
6
|
8
|
|
SLC13A5
|
0 |
0 |
4
|
1
|
3
|
8
|
|
SPG21
|
0 |
2
|
2
|
2
|
2
|
8
|
|
TMEM132E
|
0 |
0 |
1
|
1
|
6
|
8
|
|
TUBA8
|
0 |
0 |
3
|
0 |
5
|
8
|
|
VAPB
|
1
|
0 |
2
|
1
|
4
|
8
|
|
AMT
|
1
|
0 |
4
|
0 |
2
|
7
|
|
ANOS1
|
1
|
0 |
1
|
0 |
5
|
7
|
|
ATP2B2
|
0 |
0 |
2
|
1
|
4
|
7
|
|
ATP6AP2
|
0 |
0 |
1
|
1
|
5
|
7
|
|
C12orf43, HNF1A
|
0 |
1
|
3
|
1
|
2
|
7
|
|
CACNA2D2
|
0 |
0 |
2
|
3
|
2
|
7
|
|
CDKL5
|
1
|
0 |
2
|
1
|
3
|
7
|
|
CLCN1, LOC123956257
|
1
|
0 |
6
|
0 |
0 |
7
|
|
COL1A1, LOC126862586
|
3
|
0 |
1
|
0 |
3
|
7
|
|
COL4A6
|
0 |
0 |
1
|
0 |
6
|
7
|
|
COLQ
|
2
|
1
|
0 |
0 |
4
|
7
|
|
DIAPH3
|
0 |
0 |
2
|
0 |
5
|
7
|
|
DNM1
|
0 |
0 |
3
|
2
|
2
|
7
|
|
GOSR2, LRRC37A2
|
1
|
0 |
4
|
0 |
2
|
7
|
|
HOMER2
|
0 |
0 |
1
|
0 |
6
|
7
|
|
KCNJ2
|
2
|
0 |
1
|
3
|
1
|
7
|
|
LIAS
|
0 |
0 |
5
|
1
|
1
|
7
|
|
LOC126806426, TTN
|
0 |
0 |
4
|
2
|
1
|
7
|
|
LOC126806433, TTN
|
0 |
0 |
5
|
1
|
1
|
7
|
|
LOC126806913, OPA1
|
3
|
0 |
3
|
0 |
1
|
7
|
|
MFSD8
|
0 |
0 |
4
|
0 |
3
|
7
|
|
PANK2
|
0 |
0 |
2
|
3
|
2
|
7
|
|
PKD1, TSC2
|
1
|
0 |
0 |
0 |
6
|
7
|
|
PLP1, RAB9B
|
0 |
1
|
2
|
0 |
4
|
7
|
|
PROKR2
|
1
|
0 |
2
|
0 |
4
|
7
|
|
PTPN11
|
6
|
0 |
0 |
0 |
1
|
7
|
|
RELN, SLC26A5
|
0 |
0 |
3
|
0 |
4
|
7
|
|
ST3GAL3
|
0 |
0 |
0 |
1
|
6
|
7
|
|
ST3GAL5
|
0 |
1
|
1
|
1
|
4
|
7
|
|
TBL1XR1
|
0 |
0 |
3
|
0 |
4
|
7
|
|
TSPEAR
|
0 |
0 |
2
|
2
|
3
|
7
|
|
ADCY1
|
0 |
0 |
1
|
1
|
4
|
6
|
|
AFG3L2, TUBB6
|
0 |
0 |
4
|
0 |
2
|
6
|
|
ALG9
|
0 |
0 |
2
|
2
|
2
|
6
|
|
BRRIAR, ITPR1
|
0 |
0 |
2
|
2
|
2
|
6
|
|
CACNA2D2, LOC127898564
|
0 |
0 |
0 |
2
|
4
|
6
|
|
CACNB4, LOC129934925
|
0 |
0 |
1
|
2
|
3
|
6
|
|
CAV3
|
0 |
1
|
1
|
1
|
3
|
6
|
|
CNTN1
|
0 |
0 |
1
|
0 |
5
|
6
|
|
CPA6
|
0 |
0 |
4
|
1
|
1
|
6
|
|
CUL4B
|
0 |
0 |
2
|
1
|
3
|
6
|
|
ELMOD3
|
0 |
0 |
0 |
2
|
4
|
6
|
|
EPM2A, EPM2A-DT, LOC129997381
|
0 |
0 |
2
|
0 |
4
|
6
|
|
EPS8
|
0 |
0 |
0 |
0 |
6
|
6
|
|
ERCC2
|
0 |
0 |
1
|
0 |
5
|
6
|
|
FGD1
|
0 |
0 |
3
|
1
|
2
|
6
|
|
FGFR2
|
0 |
0 |
1
|
0 |
5
|
6
|
|
GABRB2
|
0 |
0 |
2
|
1
|
3
|
6
|
|
KCNQ1
|
0 |
0 |
4
|
0 |
2
|
6
|
|
KCTD7
|
0 |
0 |
3
|
2
|
1
|
6
|
|
LOC126862361, SLC12A3
|
2
|
0 |
2
|
0 |
2
|
6
|
|
LOC129935183, TTN
|
0 |
0 |
4
|
0 |
2
|
6
|
|
LOC130009366, SACS
|
0 |
0 |
5
|
0 |
1
|
6
|
|
MAF, WWOX
|
0 |
0 |
2
|
0 |
4
|
6
|
|
MET
|
0 |
0 |
1
|
0 |
5
|
6
|
|
MITF
|
0 |
0 |
0 |
2
|
4
|
6
|
|
NARS2
|
0 |
0 |
3
|
0 |
3
|
6
|
|
NDE1
|
1
|
0 |
3
|
0 |
2
|
6
|
|
PEX7
|
1
|
1
|
2
|
1
|
1
|
6
|
|
PRIMA1
|
0 |
0 |
2
|
1
|
3
|
6
|
|
RBFOX1
|
0 |
0 |
1
|
2
|
3
|
6
|
|
RNASEH2A
|
0 |
0 |
3
|
0 |
3
|
6
|
|
SLITRK6
|
0 |
0 |
0 |
0 |
6
|
6
|
|
SMC1A
|
0 |
0 |
1
|
1
|
4
|
6
|
|
SNAP29
|
1
|
0 |
1
|
4
|
0 |
6
|
|
SPTLC1
|
2
|
0 |
1
|
0 |
3
|
6
|
|
STAR
|
3
|
1
|
0 |
0 |
2
|
6
|
|
STX1B
|
0 |
0 |
0 |
0 |
6
|
6
|
|
VHL
|
3
|
1
|
0 |
0 |
2
|
6
|
|
WDR45
|
0 |
1
|
1
|
2
|
2
|
6
|
|
ACTB
|
1
|
0 |
0 |
0 |
4
|
5
|
|
ATP1A2, LOC126805890
|
0 |
0 |
4
|
0 |
1
|
5
|
|
ATP6V1B1
|
0 |
0 |
1
|
0 |
4
|
5
|
|
BBS1, ZDHHC24
|
1
|
0 |
0 |
0 |
4
|
5
|
|
BICD2
|
0 |
0 |
4
|
0 |
1
|
5
|
|
CATIP, PNKD
|
0 |
0 |
1
|
0 |
4
|
5
|
|
CC2D2A
|
0 |
0 |
0 |
1
|
4
|
5
|
|
CDKL5, RS1
|
0 |
0 |
2
|
0 |
3
|
5
|
|
CHKB, CHKB-CPT1B
|
0 |
0 |
2
|
1
|
2
|
5
|
|
CHRNB1
|
1
|
0 |
1
|
0 |
3
|
5
|
|
CHRNE
|
0 |
1
|
0 |
0 |
4
|
5
|
|
CLDN14
|
0 |
0 |
0 |
1
|
4
|
5
|
|
CPAP, RNF17
|
0 |
0 |
2
|
1
|
2
|
5
|
|
DIAPH1
|
0 |
0 |
1
|
1
|
3
|
5
|
|
EDNRB
|
0 |
0 |
0 |
1
|
4
|
5
|
|
EIF2B3
|
0 |
0 |
1
|
1
|
3
|
5
|
|
EPS8L2
|
0 |
0 |
3
|
0 |
2
|
5
|
|
ESRRB
|
0 |
0 |
1
|
0 |
4
|
5
|
|
GCH1, LOC130055692
|
1
|
1
|
1
|
0 |
2
|
5
|
|
GFPT1
|
0 |
1
|
0 |
0 |
4
|
5
|
|
GH-LCR, GH1
|
2
|
0 |
0 |
0 |
3
|
5
|
|
GHR
|
0 |
0 |
0 |
0 |
5
|
5
|
|
GPC3
|
0 |
0 |
2
|
0 |
3
|
5
|
|
GRN, LOC125177489
|
0 |
2
|
0 |
1
|
2
|
5
|
|
HSD3B2
|
3
|
0 |
0 |
2
|
0 |
5
|
|
ILDR1
|
0 |
0 |
0 |
0 |
5
|
5
|
|
INS, INS-IGF2
|
1
|
0 |
1
|
0 |
3
|
5
|
|
KCNA2
|
0 |
0 |
1
|
1
|
3
|
5
|
|
KCNQ4
|
0 |
0 |
0 |
2
|
3
|
5
|
|
KIF1A, LOC126806583
|
0 |
0 |
2
|
1
|
2
|
5
|
|
KISS1R
|
0 |
0 |
1
|
0 |
4
|
5
|
|
KLHL9
|
0 |
0 |
2
|
1
|
2
|
5
|
|
LGI1
|
0 |
0 |
1
|
2
|
2
|
5
|
|
MHRT, MYH7
|
0 |
0 |
2
|
2
|
1
|
5
|
|
OSBPL2
|
0 |
0 |
3
|
0 |
2
|
5
|
|
OTOA
|
0 |
0 |
2
|
1
|
2
|
5
|
|
PNPT1
|
0 |
1
|
2
|
0 |
2
|
5
|
|
POLR1D
|
0 |
0 |
0 |
0 |
5
|
5
|
|
POMGNT2
|
0 |
0 |
1
|
2
|
2
|
5
|
|
PPT1
|
1
|
0 |
2
|
0 |
2
|
5
|
|
PROP1
|
1
|
0 |
0 |
0 |
4
|
5
|
|
RXYLT1
|
0 |
0 |
2
|
0 |
3
|
5
|
|
SEMA3E
|
0 |
0 |
0 |
1
|
4
|
5
|
|
SIGMAR1
|
0 |
0 |
3
|
0 |
2
|
5
|
|
SLC35A2
|
0 |
0 |
1
|
2
|
2
|
5
|
|
SRPX2
|
0 |
0 |
1
|
0 |
4
|
5
|
|
TACR3
|
0 |
0 |
0 |
1
|
4
|
5
|
|
TIA1
|
0 |
1
|
1
|
0 |
3
|
5
|
|
TUBB2B
|
0 |
0 |
2
|
0 |
3
|
5
|
|
USH1C
|
0 |
0 |
0 |
1
|
4
|
5
|
|
ABHD12
|
0 |
0 |
0 |
2
|
2
|
4
|
|
AQP2
|
2
|
2
|
0 |
0 |
0 |
4
|
|
ARFGEF1-DT, CPA6
|
0 |
0 |
0 |
0 |
4
|
4
|
|
ARHGEF9
|
0 |
0 |
2
|
2
|
0 |
4
|
|
ARX
|
0 |
1
|
0 |
0 |
3
|
4
|
|
BIN1
|
0 |
0 |
1
|
2
|
1
|
4
|
|
BSND
|
0 |
0 |
1
|
0 |
3
|
4
|
|
C10orf105, CDH23
|
0 |
0 |
0 |
0 |
4
|
4
|
|
CACNA1A, LOC126862865
|
2
|
0 |
2
|
0 |
0 |
4
|
|
CCDC50
|
0 |
0 |
1
|
0 |
3
|
4
|
|
CEACAM16
|
0 |
0 |
2
|
0 |
2
|
4
|
|
CHRNA4, LOC100130587
|
0 |
0 |
1
|
1
|
2
|
4
|
|
CLCNKB
|
2
|
0 |
0 |
0 |
2
|
4
|
|
CLPP
|
0 |
0 |
0 |
0 |
4
|
4
|
|
CRPPA, LOC129998005
|
0 |
1
|
0 |
1
|
2
|
4
|
|
CRYAB
|
0 |
0 |
2
|
0 |
2
|
4
|
|
CTSD, PRADX
|
0 |
0 |
0 |
2
|
2
|
4
|
|
CYP21A2, LOC106780800, TNXB
|
2
|
0 |
0 |
1
|
1
|
4
|
|
DCDC2
|
0 |
0 |
0 |
0 |
4
|
4
|
|
DNAJC5
|
0 |
0 |
0 |
0 |
4
|
4
|
|
EIF2B5
|
1
|
0 |
2
|
0 |
1
|
4
|
|
FOLR1
|
0 |
1
|
0 |
0 |
3
|
4
|
|
FOXI1
|
0 |
0 |
0 |
2
|
2
|
4
|
|
GATM
|
0 |
0 |
1
|
1
|
2
|
4
|
|
GNRHR
|
2
|
0 |
0 |
0 |
2
|
4
|
|
HSPB3
|
0 |
0 |
0 |
1
|
3
|
4
|
|
KDM5C
|
0 |
0 |
1
|
1
|
2
|
4
|
|
LAMA2, LOC123864065
|
0 |
0 |
3
|
0 |
1
|
4
|
|
LDB3, LOC110121486
|
2
|
0 |
0 |
0 |
2
|
4
|
|
LMNA, LOC129931597
|
0 |
0 |
3
|
0 |
1
|
4
|
|
LOC126860131, RELN
|
0 |
0 |
2
|
0 |
2
|
4
|
|
LOC126860531, NDRG1
|
0 |
0 |
1
|
0 |
3
|
4
|
|
LOC126860782, SETX
|
0 |
0 |
1
|
1
|
2
|
4
|
|
LOC126861509, PRICKLE1
|
0 |
0 |
2
|
0 |
2
|
4
|
|
LOC126862902, RYR1
|
0 |
0 |
1
|
1
|
2
|
4
|
|
LOC130001338, PLEC
|
0 |
0 |
0 |
1
|
3
|
4
|
|
LOC130001342, PLEC
|
0 |
0 |
3
|
0 |
1
|
4
|
|
LOC130056709, NIPA1
|
0 |
0 |
3
|
1
|
0 |
4
|
|
LOC130063807, NOTCH3
|
0 |
0 |
3
|
1
|
0 |
4
|
|
LOC130065345, PANK2
|
0 |
0 |
1
|
0 |
3
|
4
|
|
MANBA
|
0 |
0 |
1
|
0 |
3
|
4
|
|
MARVELD2
|
0 |
0 |
3
|
0 |
1
|
4
|
|
MEF2C
|
1
|
0 |
2
|
1
|
0 |
4
|
|
MTM1
|
2
|
0 |
1
|
0 |
1
|
4
|
|
P2RX2
|
0 |
0 |
0 |
1
|
3
|
4
|
|
PIGV
|
0 |
0 |
2
|
2
|
0 |
4
|
|
POLR2F, SOX10
|
0 |
1
|
1
|
1
|
1
|
4
|
|
SAMHD1
|
0 |
0 |
1
|
1
|
2
|
4
|
|
SERPINB6
|
0 |
0 |
2
|
1
|
1
|
4
|
|
SLC25A4
|
1
|
0 |
0 |
0 |
3
|
4
|
|
SLC26A5
|
0 |
0 |
3
|
0 |
1
|
4
|
|
SOD1, SOD1-DT
|
2
|
1
|
1
|
0 |
0 |
4
|
|
TMPRSS3
|
0 |
1
|
0 |
1
|
2
|
4
|
|
UBA1
|
0 |
0 |
0 |
1
|
3
|
4
|
|
USH1G
|
0 |
0 |
2
|
0 |
2
|
4
|
|
ANKH
|
0 |
0 |
0 |
2
|
1
|
3
|
|
BBS10
|
1
|
0 |
1
|
0 |
1
|
3
|
|
BBS2
|
1
|
0 |
0 |
0 |
2
|
3
|
|
CACNA1A, LOC126862866
|
0 |
0 |
1
|
1
|
1
|
3
|
|
CASK
|
0 |
0 |
1
|
0 |
2
|
3
|
|
CCM2, LOC129998395
|
2
|
1
|
0 |
0 |
0 |
3
|
|
CEP290
|
0 |
0 |
0 |
1
|
2
|
3
|
|
CLIC5
|
0 |
0 |
0 |
1
|
2
|
3
|
|
COL9A3, LOC126863084
|
0 |
0 |
1
|
0 |
2
|
3
|
|
CRH
|
0 |
0 |
0 |
0 |
3
|
3
|
|
CSTB, LOC130066788
|
0 |
1
|
1
|
0 |
1
|
3
|
|
CYP17A1
|
0 |
0 |
0 |
0 |
3
|
3
|
|
DCX
|
0 |
0 |
2
|
0 |
1
|
3
|
|
DMAC2L, L2HGDH
|
0 |
0 |
1
|
0 |
2
|
3
|
|
DNMT1
|
0 |
0 |
1
|
0 |
2
|
3
|
|
EIF2B4, GTF3C2
|
0 |
0 |
0 |
0 |
3
|
3
|
|
EMX2
|
0 |
0 |
1
|
0 |
2
|
3
|
|
ERCC3
|
0 |
0 |
1
|
0 |
2
|
3
|
|
EYA1
|
0 |
0 |
0 |
0 |
3
|
3
|
|
FA2H, LOC130059394
|
0 |
0 |
3
|
0 |
0 |
3
|
|
FGD1, TSR2
|
0 |
0 |
1
|
1
|
1
|
3
|
|
FGF23
|
0 |
0 |
0 |
0 |
3
|
3
|
|
GATAD1, PEX1
|
0 |
0 |
2
|
0 |
1
|
3
|
|
GDAP1, LOC130000622
|
0 |
1
|
0 |
1
|
1
|
3
|
|
GJC2
|
0 |
0 |
1
|
0 |
2
|
3
|
|
GRHL2
|
0 |
0 |
0 |
0 |
3
|
3
|
|
GRXCR2
|
0 |
0 |
0 |
0 |
3
|
3
|
|
GSDME
|
0 |
0 |
1
|
1
|
1
|
3
|
|
HOXB1
|
0 |
0 |
1
|
0 |
2
|
3
|
|
KARS1
|
0 |
0 |
1
|
0 |
2
|
3
|
|
KCNC3, LOC111811967
|
0 |
0 |
0 |
0 |
3
|
3
|
|
KCTD7, LOC129998533
|
0 |
0 |
3
|
0 |
0 |
3
|
|
KIRREL2, NPHS1
|
0 |
0 |
2
|
1
|
0 |
3
|
|
KMT2D, LOC126861520
|
1
|
0 |
0 |
0 |
2
|
3
|
|
LMNA, LOC126805877
|
0 |
0 |
0 |
0 |
3
|
3
|
|
LOC107303340, VHL
|
2
|
0 |
1
|
0 |
0 |
3
|
|
LOC108903148, OPTN
|
0 |
0 |
1
|
0 |
2
|
3
|
|
LOC112872299, RAB7A
|
0 |
0 |
2
|
0 |
1
|
3
|
|
LOC126805688, YARS1
|
0 |
0 |
3
|
0 |
0 |
3
|
|
LOC126860498, WASHC5
|
0 |
0 |
0 |
0 |
3
|
3
|
|
LOC126861897, MHRT, MYH7
|
0 |
0 |
2
|
0 |
1
|
3
|
|
LOC126862279, RBFOX1
|
0 |
0 |
1
|
1
|
1
|
3
|
|
LOC129992585, SGCB
|
0 |
0 |
2
|
1
|
0 |
3
|
|
LOC130001334, PLEC
|
0 |
0 |
2
|
0 |
1
|
3
|
|
LOC130001681, SIGMAR1
|
0 |
0 |
1
|
0 |
2
|
3
|
|
LOC130009747, SUCLA2
|
0 |
0 |
2
|
0 |
1
|
3
|
|
LOC130056973, SPG11
|
1
|
0 |
0 |
2
|
0 |
3
|
|
LOC130064454, PRX
|
0 |
0 |
2
|
0 |
1
|
3
|
|
LOC130068339, UBQLN2
|
0 |
0 |
2
|
0 |
1
|
3
|
|
ME2
|
0 |
0 |
3
|
0 |
0 |
3
|
|
MIF4GD-DT, SLC25A19
|
0 |
0 |
1
|
0 |
2
|
3
|
|
MIR6511B1, PKD1
|
0 |
0 |
2
|
0 |
1
|
3
|
|
PAFAH1B1
|
0 |
0 |
2
|
0 |
1
|
3
|
|
PAK3
|
0 |
0 |
0 |
1
|
2
|
3
|
|
PAX3
|
0 |
0 |
0 |
0 |
3
|
3
|
|
PDHA1
|
0 |
0 |
2
|
0 |
1
|
3
|
|
PIGA
|
0 |
0 |
1
|
0 |
2
|
3
|
|
POLR1C
|
0 |
0 |
1
|
0 |
2
|
3
|
|
POMGNT1
|
0 |
0 |
2
|
0 |
1
|
3
|
|
POU4F3, RBM27-POU4F3
|
0 |
0 |
1
|
0 |
2
|
3
|
|
PQBP1
|
0 |
0 |
0 |
0 |
3
|
3
|
|
RDX
|
0 |
0 |
1
|
1
|
1
|
3
|
|
RNASEH2C
|
0 |
0 |
0 |
1
|
2
|
3
|
|
ROR1
|
0 |
0 |
0 |
0 |
3
|
3
|
|
S1PR2
|
0 |
0 |
0 |
1
|
2
|
3
|
|
SIX5
|
0 |
0 |
2
|
0 |
1
|
3
|
|
SLC17A8
|
0 |
0 |
1
|
0 |
2
|
3
|
|
SLC25A19
|
0 |
0 |
1
|
1
|
1
|
3
|
|
SNAP25
|
0 |
0 |
1
|
1
|
1
|
3
|
|
SOS1
|
1
|
0 |
1
|
1
|
0 |
3
|
|
SPTLC2
|
1
|
0 |
0 |
0 |
2
|
3
|
|
SYNE4
|
0 |
0 |
0 |
2
|
1
|
3
|
|
TNNT1
|
0 |
0 |
0 |
1
|
2
|
3
|
|
TPM3
|
1
|
1
|
0 |
1
|
0 |
3
|
|
ACAD9
|
2
|
0 |
0 |
0 |
0 |
2
|
|
ACTA1
|
0 |
0 |
1
|
0 |
1
|
2
|
|
AIFM1, RAB33A
|
0 |
0 |
0 |
0 |
2
|
2
|
|
ALG14
|
1
|
0 |
1
|
0 |
0 |
2
|
|
ANAPC15, LRTOMT, TOMT
|
0 |
0 |
1
|
0 |
1
|
2
|
|
AP5Z1, LOC129997861
|
0 |
0 |
1
|
1
|
0 |
2
|
|
ATP2A2, LOC126861638
|
0 |
0 |
0 |
1
|
1
|
2
|
|
ATP7A
|
0 |
0 |
2
|
0 |
0 |
2
|
|
BBS1
|
0 |
0 |
1
|
0 |
1
|
2
|
|
BCS1L
|
0 |
0 |
0 |
0 |
2
|
2
|
|
CACNA2D2, LOC101928965, LOC127898564
|
0 |
0 |
0 |
2
|
0 |
2
|
|
CAPN3, LOC126862115
|
1
|
0 |
1
|
0 |
0 |
2
|
|
CDAN1
|
0 |
1
|
1
|
0 |
0 |
2
|
|
CDC14A
|
0 |
0 |
0 |
0 |
2
|
2
|
|
CEMIP, LOC126862194
|
0 |
0 |
1
|
0 |
1
|
2
|
|
CHD7, LOC126860403
|
0 |
0 |
0 |
1
|
1
|
2
|
|
CHRNA4, LOC126863087
|
0 |
0 |
2
|
0 |
0 |
2
|
|
CHRNE, LOC130060040
|
0 |
0 |
2
|
0 |
0 |
2
|
|
CHSY1, LOC130058068
|
0 |
0 |
0 |
0 |
2
|
2
|
|
CIB2
|
0 |
0 |
0 |
1
|
1
|
2
|
|
CLRN1
|
0 |
0 |
0 |
1
|
1
|
2
|
|
COCH
|
0 |
0 |
1
|
0 |
1
|
2
|
|
COL4A3, LOC129935730
|
0 |
0 |
1
|
0 |
1
|
2
|
|
COQ2
|
0 |
0 |
2
|
0 |
0 |
2
|
|
CUBN
|
0 |
0 |
2
|
0 |
0 |
2
|
|
CUL4B, LOC113845788
|
0 |
0 |
2
|
0 |
0 |
2
|
|
CYP11B1, LOC110673972
|
0 |
0 |
2
|
0 |
0 |
2
|
|
CYP21A2, LOC106780800, LOC110631417
|
0 |
0 |
0 |
0 |
2
|
2
|
|
DEAF1, LOC126861109
|
0 |
0 |
0 |
0 |
2
|
2
|
|
DPAGT1, LOC126861360
|
0 |
0 |
1
|
1
|
0 |
2
|
|
DPM2
|
0 |
0 |
0 |
0 |
2
|
2
|
|
DYNC1H1, LOC126862060
|
0 |
0 |
1
|
0 |
1
|
2
|
|
ECHS1
|
1
|
0 |
1
|
0 |
0 |
2
|
|
EIF2B4
|
0 |
0 |
0 |
0 |
2
|
2
|
|
ESPN
|
0 |
0 |
0 |
0 |
2
|
2
|
|
FGF3
|
0 |
0 |
0 |
0 |
2
|
2
|
|
FKBP14
|
1
|
0 |
1
|
0 |
0 |
2
|
|
GAA
|
0 |
0 |
2
|
0 |
0 |
2
|
|
GBA1, LOC106627981
|
2
|
0 |
0 |
0 |
0 |
2
|
|
GIPC3
|
0 |
0 |
1
|
0 |
1
|
2
|
|
GMPPB
|
0 |
0 |
2
|
0 |
0 |
2
|
|
GOSR2, LOC126862578, LRRC37A2
|
0 |
0 |
1
|
0 |
1
|
2
|
|
GRXCR1
|
0 |
0 |
0 |
0 |
2
|
2
|
|
HGF
|
0 |
0 |
1
|
0 |
1
|
2
|
|
ITGA7, LOC126861535
|
0 |
0 |
1
|
0 |
1
|
2
|
|
KCNA1, LOC130007218
|
0 |
0 |
1
|
1
|
0 |
2
|
|
LARS1
|
0 |
0 |
2
|
0 |
0 |
2
|
|
LEPR, LOC122094844
|
0 |
0 |
1
|
0 |
1
|
2
|
|
LOC107982234, WT1
|
0 |
0 |
0 |
0 |
2
|
2
|
|
LOC112533671, TSEN54
|
0 |
0 |
0 |
0 |
2
|
2
|
|
LOC112840921, OTOF
|
0 |
0 |
0 |
1
|
1
|
2
|
|
LOC122152296, USH2A
|
0 |
0 |
1
|
1
|
0 |
2
|
|
LOC125467768, PCDH19
|
0 |
1
|
0 |
0 |
1
|
2
|
|
LOC126806373, NEB
|
0 |
0 |
0 |
0 |
2
|
2
|
|
LOC126860130, RELN, SLC26A5
|
0 |
0 |
0 |
0 |
2
|
2
|
|
LOC126862278, RBFOX1
|
0 |
0 |
0 |
0 |
2
|
2
|
|
LOC126863145, TRIOBP
|
0 |
0 |
0 |
1
|
1
|
2
|
|
LOC129995449, SQSTM1
|
0 |
0 |
1
|
0 |
1
|
2
|
|
LOC130067862, SCO2, TYMP
|
0 |
0 |
0 |
0 |
2
|
2
|
|
LOC130068621, NDUFA1
|
0 |
0 |
0 |
0 |
2
|
2
|
|
LZTR1
|
1
|
1
|
0 |
0 |
0 |
2
|
|
MATR3
|
1
|
0 |
0 |
0 |
1
|
2
|
|
MIR3936HG, SLC22A4
|
0 |
0 |
0 |
0 |
2
|
2
|
|
MIR6084, PINK1
|
0 |
0 |
1
|
0 |
1
|
2
|
|
MIR96
|
0 |
0 |
0 |
0 |
2
|
2
|
|
MPV17
|
1
|
1
|
0 |
0 |
0 |
2
|
|
MT-TK
|
0 |
0 |
1
|
1
|
0 |
2
|
|
MT-TS2
|
0 |
0 |
1
|
0 |
1
|
2
|
|
NOC3L, PLCE1
|
0 |
0 |
2
|
0 |
0 |
2
|
|
NPC1
|
0 |
1
|
1
|
0 |
0 |
2
|
|
NR2F1
|
0 |
0 |
0 |
0 |
2
|
2
|
|
NR3C2
|
2
|
0 |
0 |
0 |
0 |
2
|
|
PCCB
|
0 |
2
|
0 |
0 |
0 |
2
|
|
PDCD10
|
1
|
1
|
0 |
0 |
0 |
2
|
|
PFN1
|
0 |
0 |
2
|
0 |
0 |
2
|
|
PROK2
|
1
|
0 |
1
|
0 |
0 |
2
|
|
PURA
|
0 |
0 |
1
|
0 |
1
|
2
|
|
RARS2
|
0 |
1
|
1
|
0 |
0 |
2
|
|
RRM2B
|
0 |
0 |
1
|
0 |
1
|
2
|
|
SGCE
|
0 |
0 |
2
|
0 |
0 |
2
|
|
SHANK3
|
0 |
0 |
0 |
0 |
2
|
2
|
|
SLC19A2
|
0 |
0 |
1
|
0 |
1
|
2
|
|
SMS
|
0 |
0 |
1
|
0 |
1
|
2
|
|
TFAP2A
|
0 |
0 |
0 |
0 |
2
|
2
|
|
TGFBR2
|
0 |
0 |
1
|
0 |
1
|
2
|
|
TK2
|
0 |
0 |
0 |
0 |
2
|
2
|
|
TMEM67
|
0 |
0 |
0 |
0 |
2
|
2
|
|
TMEM70
|
1
|
0 |
1
|
0 |
0 |
2
|
|
TPM2
|
0 |
0 |
0 |
1
|
1
|
2
|
|
TPRN
|
0 |
0 |
1
|
0 |
1
|
2
|
|
TYMP
|
0 |
0 |
0 |
0 |
2
|
2
|
|
VRK1
|
0 |
0 |
0 |
0 |
2
|
2
|
|
intergenic
|
0 |
0 |
0 |
0 |
1
|
1
|
|
ABCA3
|
0 |
1
|
0 |
0 |
0 |
1
|
|
ABCC8, KCNJ11
|
0 |
0 |
0 |
0 |
1
|
1
|
|
ACTC1, GJD2-DT
|
0 |
0 |
1
|
0 |
0 |
1
|
|
ACTG1, LOC130061940
|
0 |
0 |
0 |
0 |
1
|
1
|
|
ADA
|
1
|
0 |
0 |
0 |
0 |
1
|
|
ADGRV1, LOC129994205
|
0 |
0 |
0 |
1
|
0 |
1
|
|
ADNP
|
1
|
0 |
0 |
0 |
0 |
1
|
|
AGRN, LOC126805576
|
0 |
0 |
0 |
0 |
1
|
1
|
|
AHI1
|
0 |
0 |
0 |
0 |
1
|
1
|
|
AKT2
|
0 |
0 |
1
|
0 |
0 |
1
|
|
ALMS1, LOC126806252
|
0 |
0 |
1
|
0 |
0 |
1
|
|
AMT, NICN1
|
0 |
0 |
0 |
0 |
1
|
1
|
|
ANGPT2, MCPH1
|
0 |
0 |
1
|
0 |
0 |
1
|
|
ANKRD11, TRAPPC2L
|
0 |
0 |
0 |
1
|
0 |
1
|
|
APOB
|
1
|
0 |
0 |
0 |
0 |
1
|
|
ARID1A
|
0 |
0 |
1
|
0 |
0 |
1
|
|
ARSL
|
1
|
0 |
0 |
0 |
0 |
1
|
|
ARX, LOC109610631
|
1
|
0 |
0 |
0 |
0 |
1
|
|
ASAH1, LOC129999940
|
0 |
0 |
1
|
0 |
0 |
1
|
|
ASPM, LOC129932155
|
0 |
0 |
0 |
0 |
1
|
1
|
|
ASXL1
|
1
|
0 |
0 |
0 |
0 |
1
|
|
ATL1, MAP4K5
|
0 |
0 |
0 |
0 |
1
|
1
|
|
ATN1
|
0 |
0 |
1
|
0 |
0 |
1
|
|
ATP13A2, LOC129929540
|
0 |
0 |
0 |
1
|
0 |
1
|
|
ATP1A3, LOC130064543
|
0 |
0 |
0 |
0 |
1
|
1
|
|
ATP6V1B2
|
0 |
0 |
0 |
0 |
1
|
1
|
|
B3GNT4, DIABLO
|
0 |
0 |
0 |
0 |
1
|
1
|
|
B4GAT1
|
0 |
0 |
1
|
0 |
0 |
1
|
|
BSCL2, GNG3, HNRNPUL2-BSCL2
|
0 |
0 |
0 |
0 |
1
|
1
|
|
C17orf107, CHRNE, MINK1
|
1
|
0 |
0 |
0 |
0 |
1
|
|
CABP2
|
0 |
0 |
0 |
0 |
1
|
1
|
|
CACNA2D2, CYB561D2, LOC127898564
|
0 |
0 |
1
|
0 |
0 |
1
|
|
CAV3, SSUH2
|
1
|
0 |
0 |
0 |
0 |
1
|
|
CCNF, TBC1D24
|
0 |
0 |
0 |
1
|
0 |
1
|
|
CEMIP, MESD
|
0 |
0 |
0 |
0 |
1
|
1
|
|
CFL2
|
0 |
0 |
0 |
1
|
0 |
1
|
|
CFTR, LOC113633877
|
1
|
0 |
0 |
0 |
0 |
1
|
|
CHRNA7
|
0 |
0 |
0 |
1
|
0 |
1
|
|
CHRNB1, LOC130060147
|
0 |
0 |
1
|
0 |
0 |
1
|
|
CHRNE, LOC130060041
|
0 |
0 |
0 |
1
|
0 |
1
|
|
CISD2, LOC129992892
|
0 |
0 |
0 |
1
|
0 |
1
|
|
CIZ1, DNM1
|
0 |
0 |
0 |
0 |
1
|
1
|
|
CLCC1, GPSM2
|
0 |
0 |
0 |
0 |
1
|
1
|
|
CLCN1, FAM131B
|
1
|
0 |
0 |
0 |
0 |
1
|
|
CLN5, LOC130009913
|
0 |
0 |
0 |
0 |
1
|
1
|
|
CNTNAP1
|
1
|
0 |
0 |
0 |
0 |
1
|
|
CNTNAP2, LOC126860216
|
0 |
0 |
0 |
1
|
0 |
1
|
|
COG4
|
1
|
0 |
0 |
0 |
0 |
1
|
|
COL11A1, LOC126805814
|
0 |
0 |
0 |
0 |
1
|
1
|
|
COL3A1
|
0 |
0 |
0 |
0 |
1
|
1
|
|
COL5A2
|
0 |
0 |
1
|
0 |
0 |
1
|
|
COL6A3, LOC126806573
|
0 |
0 |
0 |
0 |
1
|
1
|
|
COL7A1
|
1
|
0 |
0 |
0 |
0 |
1
|
|
CPT2, LOC129930561
|
0 |
0 |
1
|
0 |
0 |
1
|
|
CREBBP
|
0 |
0 |
1
|
0 |
0 |
1
|
|
CRH, LOC130000523
|
0 |
0 |
0 |
1
|
0 |
1
|
|
CRYL1, IFT88
|
0 |
0 |
1
|
0 |
0 |
1
|
|
CRYM
|
0 |
0 |
0 |
0 |
1
|
1
|
|
CYP21A2
|
0 |
0 |
1
|
0 |
0 |
1
|
|
CYP21A2, TNXB
|
0 |
0 |
1
|
0 |
0 |
1
|
|
DCDC2, KAAG1
|
0 |
0 |
1
|
0 |
0 |
1
|
|
DGUOK
|
0 |
0 |
1
|
0 |
0 |
1
|
|
DLX5
|
0 |
0 |
1
|
0 |
0 |
1
|
|
DM1, LOC107075317, SIX5
|
0 |
0 |
0 |
0 |
1
|
1
|
|
DNM1, LOC113839516
|
0 |
0 |
0 |
0 |
1
|
1
|
|
DOCK7, LOC129930655
|
0 |
0 |
1
|
0 |
0 |
1
|
|
DOCK8
|
0 |
1
|
0 |
0 |
0 |
1
|
|
DPAGT1
|
0 |
0 |
1
|
0 |
0 |
1
|
|
DSP
|
0 |
1
|
0 |
0 |
0 |
1
|
|
DYSF, LOC122787137
|
0 |
0 |
0 |
0 |
1
|
1
|
|
EDN3
|
0 |
0 |
0 |
0 |
1
|
1
|
|
EEF1A2, LOC132090595
|
0 |
0 |
0 |
0 |
1
|
1
|
|
EMX2, EMX2OS
|
0 |
0 |
0 |
0 |
1
|
1
|
|
ESPN, LOC129929241
|
0 |
0 |
1
|
0 |
0 |
1
|
|
ETHE1
|
1
|
0 |
0 |
0 |
0 |
1
|
|
EYA4, TARID
|
0 |
0 |
1
|
0 |
0 |
1
|
|
F13A1
|
1
|
0 |
0 |
0 |
0 |
1
|
|
FAM171A2, GRN
|
1
|
0 |
0 |
0 |
0 |
1
|
|
FBN1
|
0 |
0 |
0 |
0 |
1
|
1
|
|
FGF8
|
0 |
0 |
0 |
0 |
1
|
1
|
|
FLNC, LOC129999273
|
0 |
0 |
0 |
0 |
1
|
1
|
|
FOXC2
|
0 |
1
|
0 |
0 |
0 |
1
|
|
FOXP3
|
1
|
0 |
0 |
0 |
0 |
1
|
|
GAMT, LOC130062945
|
0 |
0 |
0 |
0 |
1
|
1
|
|
GATA3
|
0 |
0 |
0 |
0 |
1
|
1
|
|
GATA3, LOC130003278
|
0 |
0 |
0 |
0 |
1
|
1
|
|
GLA, RPL36A-HNRNPH2
|
0 |
0 |
1
|
0 |
0 |
1
|
|
GLUD1, LOC130004254
|
0 |
0 |
0 |
0 |
1
|
1
|
|
GLUD1, SHLD2
|
0 |
0 |
0 |
1
|
0 |
1
|
|
GNAI3
|
0 |
1
|
0 |
0 |
0 |
1
|
|
GNRH1
|
0 |
0 |
0 |
0 |
1
|
1
|
|
GRHL2, LOC126860461
|
0 |
0 |
0 |
0 |
1
|
1
|
|
GRM1, LOC126859821
|
0 |
0 |
0 |
0 |
1
|
1
|
|
HADH
|
0 |
0 |
1
|
0 |
0 |
1
|
|
HADHB
|
0 |
1
|
0 |
0 |
0 |
1
|
|
HPGD
|
1
|
0 |
0 |
0 |
0 |
1
|
|
HRAS, LRRC56
|
1
|
0 |
0 |
0 |
0 |
1
|
|
HSD17B10
|
0 |
0 |
1
|
0 |
0 |
1
|
|
IFIH1
|
0 |
0 |
1
|
0 |
0 |
1
|
|
IGHMBP2, LOC126861245
|
0 |
0 |
0 |
0 |
1
|
1
|
|
INS, TH
|
0 |
0 |
0 |
0 |
1
|
1
|
|
JAG1
|
0 |
0 |
1
|
0 |
0 |
1
|
|
KARS1, LOC126862402
|
0 |
0 |
1
|
0 |
0 |
1
|
|
KCNE1
|
0 |
0 |
0 |
1
|
0 |
1
|
|
KCNH5
|
1
|
0 |
0 |
0 |
0 |
1
|
|
KCNQ5
|
0 |
1
|
0 |
0 |
0 |
1
|
|
KDM6A
|
0 |
0 |
1
|
0 |
0 |
1
|
|
KIFBP, LOC130003959
|
0 |
0 |
1
|
0 |
0 |
1
|
|
KRT1
|
1
|
0 |
0 |
0 |
0 |
1
|
|
LAMA2, LOC126859784
|
0 |
0 |
1
|
0 |
0 |
1
|
|
LIAS, LOC112939935
|
0 |
0 |
0 |
1
|
0 |
1
|
|
LMNB2, LOC130063065
|
0 |
0 |
0 |
0 |
1
|
1
|
|
LMNB2, LOC130063066
|
0 |
0 |
0 |
0 |
1
|
1
|
|
LMNB2, MIR7108
|
0 |
0 |
0 |
0 |
1
|
1
|
|
LOC108021846, SOX9
|
0 |
1
|
0 |
0 |
0 |
1
|
|
LOC114803470, SCN8A
|
0 |
0 |
0 |
0 |
1
|
1
|
|
LOC123956210, SLC26A4
|
0 |
0 |
0 |
0 |
1
|
1
|
|
LOC126653398, TSPEAR
|
0 |
0 |
0 |
1
|
0 |
1
|
|
LOC126806878, TBL1XR1
|
0 |
0 |
0 |
0 |
1
|
1
|
|
LOC126859871, PRKN
|
0 |
0 |
0 |
0 |
1
|
1
|
|
LOC126861898, MYH7
|
0 |
0 |
0 |
1
|
0 |
1
|
|
LOC126862500, MYH2, MYHAS
|
0 |
0 |
1
|
0 |
0 |
1
|
|
LOC126862757, TCF4
|
0 |
0 |
0 |
0 |
1
|
1
|
|
LOC126863207, MID1
|
1
|
0 |
0 |
0 |
0 |
1
|
|
LOC129929426, MFN2
|
0 |
0 |
0 |
0 |
1
|
1
|
|
LOC129930446, MMACHC
|
1
|
0 |
0 |
0 |
0 |
1
|
|
LOC129933334, OTOF
|
0 |
0 |
1
|
0 |
0 |
1
|
|
LOC129934236, ST3GAL5
|
0 |
0 |
0 |
0 |
1
|
1
|
|
LOC129935184, TTN
|
0 |
0 |
0 |
0 |
1
|
1
|
|
LOC129935185, TTN
|
0 |
0 |
0 |
0 |
1
|
1
|
|
LOC129935186, TTN
|
0 |
0 |
1
|
0 |
0 |
1
|
|
LOC129936665, SETD2
|
0 |
0 |
1
|
0 |
0 |
1
|
|
LOC130002651, STXBP1
|
0 |
0 |
0 |
0 |
1
|
1
|
|
LOC130003093, TPRN
|
0 |
0 |
0 |
1
|
0 |
1
|
|
LOC130006061, RNASEH2C
|
0 |
0 |
0 |
0 |
1
|
1
|
|
LOC130059156, TK2
|
0 |
0 |
0 |
1
|
0 |
1
|
|
LOC130062084, SMCHD1
|
0 |
0 |
0 |
0 |
1
|
1
|
|
LOC130064357, RYR1
|
0 |
0 |
0 |
0 |
1
|
1
|
|
LOC130067864, TYMP
|
0 |
0 |
1
|
0 |
0 |
1
|
|
LOC130068746, SLC9A6
|
0 |
0 |
0 |
0 |
1
|
1
|
|
LRRC51, LRTOMT
|
0 |
0 |
1
|
0 |
0 |
1
|
|
LRTOMT
|
0 |
0 |
0 |
0 |
1
|
1
|
|
MASP2, TARDBP
|
1
|
0 |
0 |
0 |
0 |
1
|
|
MED12
|
0 |
0 |
1
|
0 |
0 |
1
|
|
MIR1225, PKD1, TSC2
|
1
|
0 |
0 |
0 |
0 |
1
|
|
MIR6766, POLG
|
0 |
0 |
0 |
0 |
1
|
1
|
|
MIR6795, NOTCH3
|
1
|
0 |
0 |
0 |
0 |
1
|
|
MMACHC
|
1
|
0 |
0 |
0 |
0 |
1
|
|
MPDZ
|
0 |
0 |
1
|
0 |
0 |
1
|
|
MSRB3
|
0 |
0 |
1
|
0 |
0 |
1
|
|
MT-CO1, MT-TQ
|
0 |
0 |
0 |
0 |
1
|
1
|
|
MT-RNR1, RNR1
|
0 |
0 |
0 |
0 |
1
|
1
|
|
MT-TI
|
0 |
0 |
1
|
0 |
0 |
1
|
|
MT-TQ
|
0 |
0 |
0 |
0 |
1
|
1
|
|
MT-TS1
|
0 |
0 |
0 |
0 |
1
|
1
|
|
MYH11, NDE1
|
0 |
0 |
1
|
0 |
0 |
1
|
|
NALCN
|
0 |
1
|
0 |
0 |
0 |
1
|
|
NDP
|
0 |
0 |
1
|
0 |
0 |
1
|
|
NDUFAF5
|
1
|
0 |
0 |
0 |
0 |
1
|
|
NDUFB3
|
1
|
0 |
0 |
0 |
0 |
1
|
|
NKX2-1, SFTA3
|
0 |
1
|
0 |
0 |
0 |
1
|
|
NKX2-5
|
0 |
0 |
1
|
0 |
0 |
1
|
|
NSD1
|
1
|
0 |
0 |
0 |
0 |
1
|
|
OTC
|
1
|
0 |
0 |
0 |
0 |
1
|
|
PACRG, PRKN
|
1
|
0 |
0 |
0 |
0 |
1
|
|
PAX6
|
0 |
0 |
1
|
0 |
0 |
1
|
|
PHF6
|
0 |
0 |
1
|
0 |
0 |
1
|
|
PHKA2
|
1
|
0 |
0 |
0 |
0 |
1
|
|
PI4KA, SNAP29
|
0 |
0 |
0 |
0 |
1
|
1
|
|
PJVK
|
0 |
0 |
0 |
0 |
1
|
1
|
|
PKP2
|
1
|
0 |
0 |
0 |
0 |
1
|
|
PLD3, PRX
|
0 |
0 |
0 |
0 |
1
|
1
|
|
POU1F1
|
0 |
0 |
0 |
0 |
1
|
1
|
|
PRPS1
|
0 |
0 |
0 |
0 |
1
|
1
|
|
PRRT2
|
0 |
0 |
1
|
0 |
0 |
1
|
|
PTEN
|
1
|
0 |
0 |
0 |
0 |
1
|
|
RAB39B
|
0 |
0 |
1
|
0 |
0 |
1
|
|
RAF1
|
1
|
0 |
0 |
0 |
0 |
1
|
|
S100PBP, YARS1
|
0 |
0 |
0 |
0 |
1
|
1
|
|
SAMHD1, TLDC2
|
0 |
0 |
0 |
1
|
0 |
1
|
|
SHANK2
|
0 |
0 |
0 |
0 |
1
|
1
|
|
SHOC2
|
1
|
0 |
0 |
0 |
0 |
1
|
|
SIX1
|
0 |
0 |
0 |
1
|
0 |
1
|
|
SLC22A4
|
0 |
0 |
0 |
1
|
0 |
1
|
|
SMARCA4
|
0 |
1
|
0 |
0 |
0 |
1
|
|
SNAI2
|
0 |
0 |
1
|
0 |
0 |
1
|
|
SPTA1
|
0 |
1
|
0 |
0 |
0 |
1
|
|
SYP
|
0 |
0 |
0 |
0 |
1
|
1
|
|
TGFBR1
|
0 |
0 |
0 |
0 |
1
|
1
|
|
TMEM216
|
0 |
0 |
0 |
0 |
1
|
1
|
|
TPI1
|
0 |
0 |
1
|
0 |
0 |
1
|
|
UGT1A, UGT1A1, UGT1A10, UGT1A3, UGT1A4, UGT1A5, UGT1A6, UGT1A7, UGT1A8, UGT1A9
|
0 |
0 |
1
|
0 |
0 |
1
|
|
ZNF507
|
1
|
0 |
0 |
0 |
0 |
1
|
Condition and significance breakdown #
| Condition |
pathogenic |
likely pathogenic |
uncertain significance |
likely benign |
benign |
total |
|
not provided
|
2231
|
877
|
7852
|
1657
|
3475
|
16089
|
|
not specified
|
0 |
0 |
1191
|
1158
|
4530
|
6879
|
|
Duchenne muscular dystrophy
|
62
|
0 |
0 |
0 |
0 |
62
|
|
Tuberous sclerosis 2
|
34
|
4
|
0 |
0 |
20
|
58
|
|
Tuberous sclerosis 1
|
19
|
0 |
0 |
0 |
5
|
24
|
|
Polycystic kidney disease, adult type
|
0 |
0 |
0 |
0 |
23
|
23
|
|
Severe myoclonic epilepsy in infancy
|
22
|
0 |
0 |
0 |
0 |
22
|
|
Autosomal recessive limb-girdle muscular dystrophy type 2A
|
9
|
0 |
0 |
0 |
1
|
10
|
|
Familial hypokalemia-hypomagnesemia
|
0 |
0 |
0 |
0 |
10
|
10
|
|
Merosin deficient congenital muscular dystrophy
|
0 |
0 |
0 |
0 |
10
|
10
|
|
Microcephaly 2, primary, autosomal recessive, with or without cortical malformations
|
0 |
0 |
0 |
0 |
10
|
10
|
|
Neuropathy, hereditary sensory and autonomic, type 2A
|
0 |
0 |
0 |
0 |
10
|
10
|
|
Brain small vessel disease 1 with or without ocular anomalies
|
0 |
0 |
0 |
0 |
9
|
9
|
|
Autosomal recessive limb-girdle muscular dystrophy type 2B
|
7
|
1
|
0 |
0 |
0 |
8
|
|
Charcot-Marie-Tooth disease type 4F
|
0 |
0 |
0 |
0 |
6
|
6
|
|
Cortical dysplasia-focal epilepsy syndrome
|
0 |
0 |
0 |
0 |
6
|
6
|
|
GRN-related frontotemporal lobar degeneration with Tdp43 inclusions
|
0 |
0 |
0 |
0 |
6
|
6
|
|
Juvenile myoclonic epilepsy
|
0 |
0 |
0 |
0 |
6
|
6
|
|
Smith-Magenis syndrome
|
0 |
0 |
0 |
0 |
6
|
6
|
|
Bardet-Biedl syndrome 1
|
0 |
0 |
0 |
0 |
5
|
5
|
|
Smith-Lemli-Opitz syndrome
|
0 |
0 |
0 |
0 |
5
|
5
|
|
Spinocerebellar ataxia type 5
|
0 |
0 |
0 |
0 |
5
|
5
|
|
Autosomal recessive Alport syndrome
|
0 |
0 |
0 |
0 |
4
|
4
|
|
Autosomal recessive distal spinal muscular atrophy 1
|
0 |
0 |
0 |
0 |
4
|
4
|
|
CARASIL syndrome
|
0 |
0 |
0 |
0 |
4
|
4
|
|
Charcot-Marie-Tooth disease type 1B
|
4
|
0 |
0 |
0 |
0 |
4
|
|
Charcot-Marie-Tooth disease type 2A2
|
3
|
1
|
0 |
0 |
0 |
4
|
|
Finnish congenital nephrotic syndrome
|
0 |
0 |
0 |
0 |
4
|
4
|
|
Focal segmental glomerulosclerosis 1
|
0 |
0 |
0 |
0 |
4
|
4
|
|
Hereditary spastic paraplegia 11
|
0 |
0 |
0 |
0 |
4
|
4
|
|
Hyperinsulinemic hypoglycemia, familial, 2
|
0 |
0 |
0 |
0 |
4
|
4
|
|
Myofibrillar myopathy 6
|
0 |
0 |
0 |
0 |
4
|
4
|
|
Rett syndrome
|
4
|
0 |
0 |
0 |
0 |
4
|
|
Autosomal dominant nocturnal frontal lobe epilepsy 1
|
0 |
0 |
0 |
0 |
3
|
3
|
|
Autosomal recessive limb-girdle muscular dystrophy type 2L
|
3
|
0 |
0 |
0 |
0 |
3
|
|
Emery-Dreifuss muscular dystrophy 2, autosomal dominant
|
1
|
2
|
0 |
0 |
0 |
3
|
|
Focal segmental glomerulosclerosis 2
|
0 |
0 |
0 |
0 |
3
|
3
|
|
Hereditary spastic paraplegia 7
|
0 |
0 |
0 |
0 |
3
|
3
|
|
Hyperinsulinemic hypoglycemia, familial, 1
|
0 |
0 |
0 |
0 |
3
|
3
|
|
Hypogonadotropic hypogonadism 3 with or without anosmia
|
0 |
0 |
0 |
0 |
3
|
3
|
|
Laron-type isolated somatotropin defect
|
0 |
0 |
0 |
0 |
3
|
3
|
|
Seizures, benign familial neonatal, 1
|
0 |
0 |
0 |
0 |
3
|
3
|
|
Alzheimer disease 4
|
0 |
0 |
0 |
0 |
2
|
2
|
|
Amyotrophic lateral sclerosis type 6
|
0 |
0 |
0 |
0 |
2
|
2
|
|
Autosomal dominant optic atrophy classic form
|
0 |
0 |
0 |
0 |
2
|
2
|
|
Autosomal recessive limb-girdle muscular dystrophy type 2I
|
2
|
0 |
0 |
0 |
0 |
2
|
|
Charcot-Marie-Tooth disease axonal type 2C
|
2
|
0 |
0 |
0 |
0 |
2
|
|
Charcot-Marie-Tooth disease type 4B1
|
0 |
0 |
0 |
0 |
2
|
2
|
|
Charcot-Marie-Tooth disease, type IA
|
1
|
1
|
0 |
0 |
0 |
2
|
|
Cohen syndrome
|
0 |
0 |
0 |
0 |
2
|
2
|
|
Dilated cardiomyopathy 1A
|
1
|
1
|
0 |
0 |
0 |
2
|
|
Encephalopathy due to GLUT1 deficiency
|
0 |
0 |
0 |
0 |
2
|
2
|
|
Febrile seizures, familial, 8
|
0 |
0 |
0 |
0 |
2
|
2
|
|
Focal segmental glomerulosclerosis 5
|
0 |
0 |
0 |
0 |
2
|
2
|
|
Hereditary spastic paraplegia 8
|
0 |
0 |
0 |
0 |
2
|
2
|
|
Hyperinsulinism-hyperammonemia syndrome
|
0 |
0 |
0 |
0 |
2
|
2
|
|
Lafora disease
|
0 |
0 |
0 |
0 |
2
|
2
|
|
Metachromatic leukodystrophy
|
0 |
0 |
0 |
0 |
2
|
2
|
|
Myoclonic dystonia 11
|
0 |
0 |
0 |
0 |
2
|
2
|
|
Nephrotic syndrome, type 2
|
0 |
0 |
0 |
0 |
2
|
2
|
|
Paroxysmal nonkinesigenic dyskinesia 1
|
0 |
0 |
0 |
0 |
2
|
2
|
|
21-Hydroxylase-Deficient Congenital Adrenal Hyperplasia
|
0 |
0 |
0 |
0 |
1
|
1
|
|
Adrenoleukodystrophy
|
0 |
0 |
0 |
0 |
1
|
1
|
|
Autosomal recessive early-onset Parkinson disease 6
|
0 |
0 |
0 |
0 |
1
|
1
|
|
Autosomal recessive limb-girdle muscular dystrophy type 2C
|
1
|
0 |
0 |
0 |
0 |
1
|
|
Autosomal recessive limb-girdle muscular dystrophy type 2D
|
1
|
0 |
0 |
0 |
0 |
1
|
|
Autosomal recessive limb-girdle muscular dystrophy type 2E
|
1
|
0 |
0 |
0 |
0 |
1
|
|
Bardet-Biedl syndrome 10
|
0 |
0 |
0 |
0 |
1
|
1
|
|
Bardet-Biedl syndrome 2
|
0 |
0 |
0 |
0 |
1
|
1
|
|
Bartter disease type 4A
|
0 |
0 |
0 |
0 |
1
|
1
|
|
Cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 1
|
0 |
0 |
0 |
0 |
1
|
1
|
|
Charcot-Marie-Tooth disease X-linked dominant 1
|
1
|
0 |
0 |
0 |
0 |
1
|
|
Charcot-Marie-Tooth disease axonal type 2F
|
1
|
0 |
0 |
0 |
0 |
1
|
|
Charcot-Marie-Tooth disease type 1C
|
0 |
0 |
0 |
0 |
1
|
1
|
|
Charcot-Marie-Tooth disease type 2B1
|
1
|
0 |
0 |
0 |
0 |
1
|
|
Charcot-Marie-Tooth disease type 4A
|
1
|
0 |
0 |
0 |
0 |
1
|
|
Charcot-Marie-Tooth disease type 4C
|
1
|
0 |
0 |
0 |
0 |
1
|
|
Charcot-Marie-Tooth disease type 4J
|
1
|
0 |
0 |
0 |
0 |
1
|
|
Developmental and epileptic encephalopathy 112
|
1
|
0 |
0 |
0 |
0 |
1
|
|
Familial partial lipodystrophy, Dunnigan type
|
1
|
0 |
0 |
0 |
0 |
1
|
|
Hereditary spastic paraplegia 31
|
0 |
0 |
0 |
0 |
1
|
1
|
|
Intellectual disability, autosomal dominant 46
|
0 |
1
|
0 |
0 |
0 |
1
|
|
Migraine, familial hemiplegic, 2
|
0 |
0 |
0 |
0 |
1
|
1
|
|
Obesity due to leptin receptor gene deficiency
|
0 |
0 |
0 |
0 |
1
|
1
|
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diagnostic use or medical decision-making without review by a
genetics professional. Individuals should not change their
health behavior solely on the basis of information contained on
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If you have questions about the information contained on this
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