If a variant has more than one submission, it may be counted in more than one significance column. If this is the
case, the total number of variants will be less than the sum of the other cells.
| pathogenic |
likely pathogenic |
uncertain significance |
likely benign |
benign |
not provided |
total |
|
238
|
83
|
864
|
389
|
19
|
4
|
1557
|
Gene and significance breakdown #
Total genes and gene combinations: 7
| Gene or gene combination |
pathogenic |
likely pathogenic |
uncertain significance |
likely benign |
benign |
not provided |
total |
|
LOC107303340, VHL
|
126
|
51
|
451
|
217
|
10
|
2
|
832
|
|
VHL
|
105
|
31
|
408
|
172
|
9
|
2
|
712
|
|
BRK1, FANCD2, FANCD2OS, VHL
|
2
|
0 |
3
|
0 |
0 |
0 |
5
|
|
BRK1, FANCD2, FANCD2OS, LOC107303338, LOC107303339, LOC107303340, LOC129936148, LOC129936149, VHL
|
2
|
0 |
2
|
0 |
0 |
0 |
4
|
|
FANCD2, VHL
|
2
|
0 |
0 |
0 |
0 |
0 |
2
|
|
CEP120
|
0 |
1
|
0 |
0 |
0 |
0 |
1
|
|
IRAK2, VHL
|
1
|
0 |
0 |
0 |
0 |
0 |
1
|
Submitter and significance breakdown #
| Submitter |
pathogenic |
likely pathogenic |
uncertain significance |
likely benign |
benign |
not provided |
total |
|
Labcorp Genetics (formerly Invitae), Labcorp
|
229
|
67
|
838
|
385
|
19
|
0 |
1538
|
|
Fulgent Genetics, Fulgent Genetics
|
3
|
5
|
75
|
7
|
0 |
0 |
90
|
|
Baylor Genetics
|
5
|
2
|
82
|
0 |
0 |
0 |
89
|
|
Department of Pathology and Laboratory Medicine, Sinai Health System
|
3
|
4
|
6
|
2
|
1
|
0 |
16
|
|
Genomic Medicine Center of Excellence, King Faisal Specialist Hospital and Research Centre
|
3
|
5
|
5
|
1
|
0 |
0 |
14
|
|
OMIM
|
12
|
0 |
0 |
0 |
0 |
0 |
12
|
|
GenomeConnect - Invitae Patient Insights Network
|
0 |
0 |
0 |
0 |
0 |
4
|
4
|
|
Women's Health and Genetics/Laboratory Corporation of America, LabCorp
|
4
|
0 |
0 |
0 |
0 |
0 |
4
|
|
Oxford Medical Genetics Laboratories, Oxford University Hospitals NHS Foundation Trust
|
1
|
0 |
1
|
1
|
0 |
0 |
3
|
|
Juno Genomics, Hangzhou Juno Genomics, Inc
|
2
|
0 |
0 |
0 |
0 |
0 |
2
|
|
Laboratorio de Genetica e Diagnostico Molecular, Hospital Israelita Albert Einstein
|
0 |
0 |
2
|
0 |
0 |
0 |
2
|
|
Cellular and Molecular Biology Laboratory, University of Campania Luigi Vanvitelli
|
1
|
0 |
0 |
0 |
0 |
0 |
1
|
|
Clinical Laboratory Sciences Program (CLSP), King Saud bin Abdulaziz University for Health Sciences (KSAU-HS)
|
0 |
1
|
0 |
0 |
0 |
0 |
1
|
|
First Genomix Gene Laboratory, Genetic Diagnostics Department
|
1
|
0 |
0 |
0 |
0 |
0 |
1
|
|
Genomic Diagnostic Laboratory, Division of Genomic Diagnostics, Children's Hospital of Philadelphia
|
1
|
0 |
0 |
0 |
0 |
0 |
1
|
|
Mendelics
|
0 |
0 |
1
|
0 |
0 |
0 |
1
|
|
Victorian Clinical Genetics Services, Murdoch Childrens Research Institute
|
1
|
0 |
0 |
0 |
0 |
0 |
1
|
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