ClinVar Miner

Variants studied for DDX41-related hematologic malignancy predisposition syndrome

Included ClinVar conditions (1):
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign not provided total
36 47 139 2 6 10 217

Gene and significance breakdown #

Total genes and gene combinations: 2
Download table as spreadsheet
Gene or gene combination pathogenic likely pathogenic uncertain significance likely benign benign not provided total
DDX41 36 47 138 2 6 10 216
DNAAF3 0 0 1 0 0 0 1

Submitter and significance breakdown #

Total submitters: 26
Download table as spreadsheet
Submitter pathogenic likely pathogenic uncertain significance likely benign benign not provided total
Baylor Genetics 9 13 102 0 0 0 124
Saint-Louis Hospital, Assistance Publique Hôpitaux de Paris 13 17 1 0 0 0 31
Clinical Genomics Labs, University Health Network 12 0 17 0 0 0 29
St. Jude Molecular Pathology, St. Jude Children's Research Hospital 1 4 18 0 0 0 23
Molecular Pathology, Peter Maccallum Cancer Centre 7 10 5 0 0 0 22
ARUP Laboratories, Molecular Genetics and Genomics, ARUP Laboratories 4 0 2 2 6 0 14
Fulgent Genetics, Fulgent Genetics 1 1 9 0 0 0 11
GeneReviews 0 0 0 0 0 10 10
Institute for Genomic Medicine (IGM) Clinical Laboratory, Nationwide Children's Hospital 3 4 0 0 0 0 7
OMIM 6 0 0 0 0 0 6
Genetic Services Laboratory, University of Chicago 4 1 0 0 0 0 5
Department of Pathology and Laboratory Medicine, Sinai Health System 0 0 4 0 0 0 4
Johns Hopkins Genomics, Johns Hopkins University 1 0 3 0 0 0 4
Juno Genomics, Hangzhou Juno Genomics, Inc 2 2 0 0 0 0 4
Laboratorio de Genetica e Diagnostico Molecular, Hospital Israelita Albert Einstein 1 2 0 0 0 0 3
Genomic Medicine Center of Excellence, King Faisal Specialist Hospital and Research Centre 0 2 0 0 0 0 2
Illumina Laboratory Services, Illumina 1 1 0 0 0 0 2
Institute of Human Genetics, University of Leipzig Medical Center 1 0 1 0 0 0 2
Clinical Genetics Laboratory, University Hospital Schleswig-Holstein 1 0 0 0 0 0 1
HudsonAlpha Institute for Biotechnology, HudsonAlpha Institute for Biotechnology 1 0 0 0 0 0 1
Human Genetics Bochum, Ruhr University Bochum 0 1 0 0 0 0 1
Molecular Diagnostics Laboratory, M Health Fairview: University of Minnesota 0 1 0 0 0 0 1
Neuberg Centre For Genomic Medicine, NCGM 0 0 1 0 0 0 1
Seattle Children's Hospital Molecular Genetics Laboratory, Seattle Children's Hospital 0 0 1 0 0 0 1
Victorian Clinical Genetics Services, Murdoch Childrens Research Institute 0 0 1 0 0 0 1
Women's Health and Genetics/Laboratory Corporation of America, LabCorp 1 0 0 0 0 0 1

The information on this website is not intended for direct diagnostic use or medical decision-making without review by a genetics professional. Individuals should not change their health behavior solely on the basis of information contained on this website. The submitted information has not been verified. If you have questions about the information contained on this website, please see a health care professional.