Variants in gene WNK2 - ClinVar Miner

Minimum submission review status:		Collection method:
Minimum conflict level: Report conflict between different conditions
Gene type: Distinguish antisense genes from sense genes
Show significances as they were submitted (without aggregation into standard terms)

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic	likely pathogenic	uncertain significance	likely benign	benign	not provided	total
0	1	1881	1235	6	37	3151

Condition and significance breakdown #

Total conditions: 22

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Condition	likely pathogenic	uncertain significance	likely benign	benign	not provided	total
not specified	0	1880	1233	0	0	3113
not provided	0	1	6	6	0	13
Nonpapillary renal cell carcinoma	0	0	0	0	6	6
Melanoma	0	0	0	0	5	5
Ovarian serous cystadenocarcinoma	0	0	0	0	5	5
Cholangiocarcinoma	0	0	0	0	4	4
Gastric cancer	0	0	0	0	4	4
Thyroid cancer, nonmedullary, 1	0	0	0	0	4	4
Uterine carcinosarcoma	0	0	0	0	4	4
Cervical cancer	0	0	0	0	2	2
Colorectal cancer	0	0	0	0	2	2
Familial cancer of breast	0	0	0	0	2	2
Hepatocellular carcinoma	0	0	0	0	2	2
Lymphoma	0	0	0	0	2	2
Malignant tumor of esophagus	0	0	0	0	2	2
Thymoma	0	0	0	0	2	2
Uveal melanoma	0	0	0	0	2	2
Colon adenocarcinoma	0	0	0	0	1	1
Inborn genetic diseases	1	0	0	0	0	1
Papillary renal cell carcinoma type 1	0	0	0	0	1	1
Uterine corpus endometrial carcinoma	0	0	0	0	1	1
WNK2-related condition	0	1	0	0	0	1

Submitter and significance breakdown #

Total submitters: 6

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Submitter	likely pathogenic	uncertain significance	likely benign	benign	not provided	total
Ambry Genetics	1	1880	1233	0	0	3114
Dr. Peter K. Rogan Lab, Western University	0	0	0	0	37	37
Breakthrough Genomics, Breakthrough Genomics	0	1	2	5	0	8
Labcorp Genetics (formerly Invitae), Labcorp	0	0	2	6	0	8
CeGaT Center for Human Genetics Tuebingen	0	0	4	0	0	4
PreventionGenetics, part of Exact Sciences	0	1	0	0	0	1

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