ClinVar Miner

Variants in gene TTN

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Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign not provided total
765 5369 14506 18176 2117 438 35226

Condition and significance breakdown #

Total conditions: 185
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Condition pathogenic likely pathogenic uncertain significance likely benign benign not provided total
Dilated cardiomyopathy 1G; Autosomal recessive limb-girdle muscular dystrophy type 2J 279 3603 4440 13028 846 0 22196
not provided 348 788 8300 3783 766 100 12018
Cardiovascular phenotype 143 1018 1924 4599 408 0 8069
not specified 0 3 2771 3526 1245 2 6245
Dilated cardiomyopathy 1G 126 558 1378 250 109 2 2396
Autosomal recessive limb-girdle muscular dystrophy type 2J 32 59 1323 156 551 0 1984
Early-onset myopathy with fatal cardiomyopathy 28 33 1283 159 551 0 1941
Tibial muscular dystrophy 17 13 477 112 1303 7 1915
Myopathy, myofibrillar, 9, with early respiratory failure 12 11 480 195 1212 4 1905
Cardiomyopathy 27 112 611 593 512 3 1849
Dilated cardiomyopathy 1G; Autosomal recessive limb-girdle muscular dystrophy type 2J; Tibial muscular dystrophy; Myopathy, myofibrillar, 9, with early respiratory failure; Early-onset myopathy with fatal cardiomyopathy; Hypertrophic cardiomyopathy 9 29 98 1136 124 18 7 1410
TTN-related disorder 19 76 480 536 89 6 1202
Primary dilated cardiomyopathy 36 356 120 33 24 1 554
Dilated cardiomyopathy 1G; Hypertrophic cardiomyopathy 9 3 14 80 0 0 0 97
Ovarian serous cystadenocarcinoma 0 0 0 0 0 94 94
Primary familial dilated cardiomyopathy 22 60 0 0 0 0 82
Hypertrophic cardiomyopathy 1 0 36 38 6 0 81
Autosomal recessive titinopathy 37 20 22 0 0 0 79
Hypertrophic cardiomyopathy 9 3 11 48 3 0 0 65
Tip-toe gait 1 57 6 0 0 0 64
TTN-related myopathy 7 8 24 7 4 0 50
Nonpapillary renal cell carcinoma 0 0 0 0 0 48 48
Limb-girdle muscular dystrophy 0 1 10 11 0 0 22
Thyroid cancer, nonmedullary, 1 0 0 0 0 0 22 22
Dilated cardiomyopathy 1S 1 7 13 0 0 0 20
Primary familial hypertrophic cardiomyopathy 0 0 17 3 0 0 20
Gastric cancer 0 0 0 0 0 18 18
Inborn genetic diseases 2 1 13 1 0 0 17
Malignant tumor of esophagus 0 0 0 0 0 17 17
See cases 0 1 9 4 1 2 17
Dilated cardiomyopathy 1A 9 7 0 0 0 0 16
Melanoma 0 0 0 0 0 16 16
Acute myeloid leukemia 0 0 0 0 0 15 15
Arrhythmogenic right ventricular cardiomyopathy 0 0 5 6 2 0 13
Autosomal recessive limb-girdle muscular dystrophy type 2J; Early-onset myopathy with fatal cardiomyopathy 4 6 3 0 0 0 13
Centronuclear myopathy 2 11 1 0 0 0 13
Hypertrophic cardiomyopathy 2 0 0 1 3 1 8 13
Lung cancer 0 0 0 0 0 13 13
Congenital myopathy 3 1 7 0 1 0 12
Cervical cancer 0 0 0 0 0 11 11
Uterine corpus endometrial carcinoma 0 0 0 0 0 11 11
Ventricular tachycardia 0 1 5 5 0 0 11
Hepatocellular carcinoma 0 0 0 0 0 10 10
Long QT syndrome 0 0 5 1 4 0 10
Thymoma 0 0 0 0 0 10 10
Left ventricular noncompaction cardiomyopathy 0 6 3 0 0 0 9
Myopathy 4 1 4 0 0 0 9
Clear cell carcinoma of kidney 0 0 0 0 0 8 8
Sarcoma 0 0 0 0 0 8 8
Atrial fibrillation 0 0 2 4 1 0 7
Dilated cardiomyopathy 1G; Autosomal recessive limb-girdle muscular dystrophy type 2J; Tibial muscular dystrophy; Early-onset myopathy with fatal cardiomyopathy; Hypertrophic cardiomyopathy 9 0 4 3 0 0 0 7
Distal myopathy 0 0 7 0 0 0 7
Papillary renal cell carcinoma type 1 0 0 0 0 0 7 7
Brugada syndrome 0 0 6 0 0 0 6
Dilated cardiomyopathy 1G; Early-onset myopathy with fatal cardiomyopathy; Hypertrophic cardiomyopathy 9 0 0 6 0 0 0 6
Familial cancer of breast 0 0 0 0 0 6 6
Uterine carcinosarcoma 0 0 0 0 0 6 6
Primary dilated cardiomyopathy; Autosomal recessive limb-girdle muscular dystrophy type 2J; Tibial muscular dystrophy; Myopathy, myofibrillar, 9, with early respiratory failure 0 0 0 0 0 5 5
SUDDEN INFANT DEATH SYNDROME 2 0 3 0 0 0 5
Abnormality of neuronal migration 0 0 0 0 4 0 4
Arrhythmogenic right ventricular dysplasia 9 0 1 2 1 0 0 4
Arthrogryposis syndrome 0 0 4 0 0 0 4
Autosomal recessive limb-girdle muscular dystrophy type 2J; Tibial muscular dystrophy 0 2 2 0 0 0 4
Colon adenocarcinoma 0 0 0 0 0 4 4
Dilated cardiomyopathy 1G; Tibial muscular dystrophy; Myopathy, myofibrillar, 9, with early respiratory failure; Hypertrophic cardiomyopathy 9 1 3 0 0 0 0 4
Heart failure 0 0 0 4 0 0 4
Left ventricular hypertrophy 0 0 3 1 0 0 4
Malignant lymphoma, large B-cell, diffuse 0 0 0 0 0 4 4
Malignant tumor of urinary bladder 0 0 0 0 0 4 4
Muscular dystrophy 0 2 2 0 0 0 4
Uveal melanoma 0 0 0 0 0 4 4
Cardiomyopathy; Ventricular fibrillation 0 0 0 0 3 0 3
Cardiomyopathy; Ventricular tachycardia 0 0 0 0 3 0 3
Chronic lymphocytic leukemia/small lymphocytic lymphoma 0 0 0 0 0 3 3
Congenital long QT syndrome 0 0 3 0 0 0 3
Congenital muscular dystrophy 0 3 0 0 0 0 3
Delayed speech and language development; Abnormality of eye movement; Generalized hypotonia; Abnormal speech pattern; Delayed gross motor development; Hypotonia 0 0 3 0 0 0 3
Desmin-related myofibrillar myopathy 1 2 0 0 0 0 3
Left ventricular noncompaction 2 0 1 2 0 0 0 3
Lymphoma 0 0 0 0 0 3 3
Multiminicore myopathy 1 1 1 0 0 0 3
Myopathy, myofibrillar, 9, with early respiratory failure; Early-onset myopathy with fatal cardiomyopathy 0 2 1 0 0 0 3
Neuromuscular disease 2 1 0 0 0 0 3
Premature ventricular contraction 0 0 1 2 0 0 3
Restrictive cardiomyopathy 0 2 1 0 0 0 3
Squamous cell carcinoma of the head and neck 0 0 0 0 0 3 3
Sudden cardiac arrest 0 0 1 2 0 0 3
Supraventricular tachycardia 0 0 0 2 1 0 3
Ventricular fibrillation 0 0 1 2 0 0 3
Amyloidosis, hereditary systemic 1 0 0 0 1 1 0 2
Bilateral talipes equinovarus; Restrictive ventilatory defect; Areflexia of lower limbs; Spinal rigidity; Thoracic kyphoscoliosis 0 0 2 0 0 0 2
Cardiomyopathy; Hypertrophic cardiomyopathy 0 0 0 1 1 0 2
Cardiomyopathy; Long QT syndrome 0 0 0 0 2 0 2
Cardiomyopathy; Long QT syndrome; Heart failure 0 0 0 0 2 0 2
Colorectal cancer 0 0 0 0 0 2 2
Congenital portosystemic shunt 0 0 2 0 0 0 2
Congenital titinopathy 0 2 0 0 0 0 2
Congestive heart failure 0 0 0 2 0 0 2
Dilated and arrhythmogenic cardiomyopathy 0 2 0 0 0 0 2
Dilated cardiomyopathy 1G; Autosomal recessive limb-girdle muscular dystrophy type 2J; Early-onset myopathy with fatal cardiomyopathy; Hypertrophic cardiomyopathy 9 0 1 1 0 0 0 2
Dilated cardiomyopathy 1G; Autosomal recessive limb-girdle muscular dystrophy type 2J; Tibial muscular dystrophy; Myopathy, myofibrillar, 9, with early respiratory failure; Hypertrophic cardiomyopathy 9 0 0 0 0 0 2 2
Dilated cardiomyopathy 1G; TTN-related myopathy 0 0 2 0 0 0 2
Early-onset myopathy with fatal cardiomyopathy; Congenital titinopathy 2 0 0 0 0 0 2
Familial pancreatic carcinoma 0 0 0 0 0 2 2
Familial restrictive cardiomyopathy 0 0 2 0 0 0 2
Hereditary skeletal muscle disorder 0 0 2 0 0 0 2
Hypertrophic cardiomyopathy; Supraventricular tachycardia 0 0 0 0 2 0 2
Intellectual disability 0 0 2 0 0 0 2
Left ventricular noncompaction 0 0 2 0 0 0 2
Limb-girdle muscular dystrophy; Muscular dystrophy; Waddling gait; Proximal lower limb amyotrophy; Decreased patellar reflex 0 2 0 0 0 0 2
Ovarian cancer 0 0 0 0 0 2 2
Primary dilated cardiomyopathy; Autosomal recessive limb-girdle muscular dystrophy type 2J; Tibial muscular dystrophy; Myopathy, myofibrillar, 9, with early respiratory failure; Autosomal recessive centronuclear myopathy 0 0 0 0 0 2 2
Primary dilated cardiomyopathy; Autosomal recessive limb-girdle muscular dystrophy type 2J; Tibial muscular dystrophy; Myopathy, myofibrillar, 9, with early respiratory failure; Centronuclear myopathy 0 0 0 0 0 2 2
Primary dilated cardiomyopathy; Cardiomyopathy 0 0 0 1 1 0 2
Primary dilated cardiomyopathy; Heart failure 0 0 0 2 0 0 2
Rare genetic intellectual disability 0 0 2 0 0 0 2
Schizophrenia 0 0 2 0 0 0 2
Skeletal dysplasia 0 0 0 1 1 0 2
Squamous cell lung carcinoma 0 0 0 0 0 2 2
TTN-related cardiomyopathy 0 2 0 0 0 0 2
Third degree atrioventricular block 1 1 0 0 0 0 2
Tibial muscular dystrophy; Myopathy, myofibrillar, 9, with early respiratory failure 0 2 0 0 0 0 2
Titinopathy 0 1 1 0 0 0 2
Wolff-Parkinson-White pattern 0 2 0 0 0 0 2
Abnormality of the musculature 0 1 0 0 0 0 1
Adrenocortical carcinoma, hereditary 0 0 0 0 0 1 1
Arrhythmogenic right ventricular cardiomyopathy; Hypertrophic cardiomyopathy 0 0 0 0 1 0 1
Atrial fibrillation; Brugada syndrome; Congestive heart failure; Hypertrophic cardiomyopathy 0 0 0 1 0 0 1
Atrial fibrillation; Cardiomyopathy 0 0 0 1 0 0 1
Atrial fibrillation; Congestive heart failure; Ventricular tachycardia 0 0 0 0 1 0 1
Atrial fibrillation; Ventricular tachycardia 0 0 0 0 1 0 1
Autosomal recessive limb-girdle muscular dystrophy type 2J; Tibial muscular dystrophy; Myopathy, myofibrillar, 9, with early respiratory failure 0 1 0 0 0 0 1
Brugada syndrome; Supraventricular tachycardia; Ventricular tachycardia 0 0 0 0 1 0 1
CAP-congenital myopathy with arthrogryposis multiplex congenita without heart involvement 0 1 0 0 0 0 1
Cardiomyopathy; Brugada syndrome 0 0 0 1 0 0 1
Cardiomyopathy; Congestive heart failure; Hypertrophic cardiomyopathy 0 0 0 0 1 0 1
Cardiomyopathy; Hypertrophic cardiomyopathy; Ventricular tachycardia 0 0 0 0 1 0 1
Cardiomyopathy; Long QT syndrome; Hypertrophic cardiomyopathy 0 0 0 1 0 0 1
Cardiomyopathy; Supraventricular tachycardia 0 0 0 1 0 0 1
Cerebral palsy 0 1 0 0 0 0 1
Cholangiocarcinoma 0 0 0 0 0 1 1
Conduction disorder of the heart 0 0 1 0 0 0 1
Cystic fibrosis 0 1 0 0 0 0 1
Diastolic dysfunction 0 0 1 0 0 0 1
Dilated cardiomyopathy 1G; Autosomal recessive limb-girdle muscular dystrophy type 2J; Hypertrophic cardiomyopathy 9 0 0 1 0 0 0 1
Dilated cardiomyopathy 1G; Autosomal recessive limb-girdle muscular dystrophy type 2J; Myopathy, myofibrillar, 9, with early respiratory failure; Early-onset myopathy with fatal cardiomyopathy 0 0 1 0 0 0 1
Dilated cardiomyopathy 1G; Autosomal recessive limb-girdle muscular dystrophy type 2J; Myopathy, myofibrillar, 9, with early respiratory failure; Early-onset myopathy with fatal cardiomyopathy; Hypertrophic cardiomyopathy 9 0 0 0 0 0 1 1
Dilated cardiomyopathy 1G; Autosomal recessive limb-girdle muscular dystrophy type 2J; Tibial muscular dystrophy; Myopathy, myofibrillar, 9, with early respiratory failure; Autosomal dominant centronuclear myopathy; Early-onset myopathy with fatal cardiomyopathy 0 0 1 0 0 0 1
Dilated cardiomyopathy 1G; Autosomal recessive limb-girdle muscular dystrophy type 2J; Tibial muscular dystrophy; Myopathy, myofibrillar, 9, with early respiratory failure; Early-onset myopathy with fatal cardiomyopathy 0 0 1 0 0 0 1
Dilated cardiomyopathy 1G; Autosomal recessive limb-girdle muscular dystrophy type 2J; Tibial muscular dystrophy; Myopathy, myofibrillar, 9, with early respiratory failure; Early-onset myopathy with fatal cardiomyopathy; Myopathy 0 0 1 0 0 0 1
Dilated cardiomyopathy 1G; Myopathy, myofibrillar, 9, with early respiratory failure; Early-onset myopathy with fatal cardiomyopathy; Hypertrophic cardiomyopathy 9 0 0 0 0 0 1 1
Dilated cardiomyopathy 1G; Myopathy, myofibrillar, 9, with early respiratory failure; Hypertrophic cardiomyopathy 9 0 1 0 0 0 0 1
EBV-positive nodal T- and NK-cell lymphoma 0 0 0 1 0 0 1
Familial isolated dilated cardiomyopathy 0 1 0 0 0 0 1
Family history of cardiomyopathy 0 0 1 0 0 0 1
Hereditary inclusion-body myopathy 0 1 0 0 0 0 1
Interstitial cardiac fibrosis 0 1 0 0 0 0 1
Limb-girdle muscle weakness; Limb-girdle muscle atrophy 0 0 1 0 0 0 1
Lower limb muscle weakness 1 0 0 0 0 0 1
Mitral valve prolapse 0 1 0 0 0 0 1
Motor delay 0 0 1 0 0 0 1
Muscular dystrophy; Gait disturbance; EMG abnormality; Fatty replacement of skeletal muscle 0 0 1 0 0 0 1
Myopathy; Rimmed vacuoles; Lower limb muscle weakness 0 1 0 0 0 0 1
Neurodevelopmental delay 0 1 0 0 0 0 1
Non-compaction cardiomyopathy 0 1 0 0 0 0 1
Noncompaction cardiomyopathy 1 0 0 0 0 0 1
Orofacial cleft 1 1 0 0 0 0 0 1
Primary dilated cardiomyopathy; Arrhythmogenic right ventricular cardiomyopathy 0 0 0 1 0 0 1
Primary dilated cardiomyopathy; Atrial fibrillation 0 0 0 0 1 0 1
Primary dilated cardiomyopathy; Autosomal recessive limb-girdle muscular dystrophy type 2J; Tibial muscular dystrophy 0 0 0 0 0 1 1
Primary dilated cardiomyopathy; Brugada syndrome 0 0 0 1 0 0 1
Primary dilated cardiomyopathy; Cardiomyopathy; Low-output congestive heart failure; Noncompaction cardiomyopathy 1 0 0 0 0 0 1
Primary dilated cardiomyopathy; Myocarditis 0 1 0 0 0 0 1
Primary dilated cardiomyopathy; Myopathy, centronuclear, 2; Autosomal recessive limb-girdle muscular dystrophy type 2J; Tibial muscular dystrophy; Myopathy, myofibrillar, 9, with early respiratory failure 0 0 0 0 0 1 1
Reduced left ventricular ejection fraction; Noncompaction cardiomyopathy 0 1 0 0 0 0 1
Right ventricular cardiomyopathy 0 0 1 0 0 0 1
Short stature; Failure to thrive; Generalized muscle weakness; Delayed speech and language development; Abnormal speech pattern; Abnormality of the immune system; Hypotonia 0 0 0 1 0 0 1
Sudden cardiac death; Cardiac arrest 0 0 0 1 0 0 1
Syncope; Hypertrophic cardiomyopathy 0 0 1 0 0 0 1
Systolic heart failure 0 0 0 1 0 0 1
TNN-related disorder 1 0 0 0 0 0 1
Tuberous sclerosis 2 0 0 1 0 0 0 1
Ventricular fibrillation, paroxysmal familial, type 1 0 0 1 0 0 0 1
X-linked myopathy with postural muscle atrophy 0 0 1 0 0 0 1
autosomal dominant dilated cardiomyopathy; autosomal dominant myopathies; autosomal recessive myopathies 0 0 1 0 0 0 1

Submitter and significance breakdown #

Total submitters: 208
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign not provided total
Labcorp Genetics (formerly Invitae), Labcorp 280 3607 4440 13067 847 0 22238
Ambry Genetics 112 976 1903 4599 408 0 7997
GeneDx 254 387 2258 2964 990 92 6945
Revvity Omics, Revvity 16 92 3513 68 1 0 3690
Eurofins Ntd Llc (ga) 9 64 2364 268 250 0 2954
Women's Health and Genetics/Laboratory Corporation of America, LabCorp 23 94 1222 1073 422 0 2834
Laboratory for Molecular Medicine, Mass General Brigham Personalized Medicine 8 145 1117 767 477 2 2515
CeGaT Center for Human Genetics Tuebingen 29 96 1028 1162 68 0 2383
Molecular Diagnostic Laboratory for Inherited Cardiovascular Disease, Montreal Heart Institute 64 55 41 1434 404 0 1997
CHEO Genetics Diagnostic Laboratory, Children's Hospital of Eastern Ontario 24 101 598 568 510 0 1801
Illumina Laboratory Services, Illumina 3 20 1270 452 1029 0 1591
Mayo Clinic Laboratories, Mayo Clinic 16 39 768 284 365 0 1472
PreventionGenetics, part of Exact Sciences 11 58 468 585 267 0 1389
Athena Diagnostics 6 8 583 175 533 0 1305
Fulgent Genetics, Fulgent Genetics 18 57 1041 121 16 0 1253
Clinical Genetics, Academic Medical Center 5 32 212 68 812 0 1129
Clinical Genetics DNA and cytogenetics Diagnostics Lab, Erasmus MC, Erasmus Medical Center 6 9 186 441 335 0 977
ARUP Laboratories, Molecular Genetics and Genomics, ARUP Laboratories 3 16 356 276 277 0 928
Joint Genome Diagnostic Labs from Nijmegen and Maastricht, Radboudumc and MUMC+ 9 21 114 216 304 0 664
Biesecker Lab/Clinical Genomics Section, National Institutes of Health 0 0 319 154 189 0 662
Diagnostic Laboratory, Department of Genetics, University Medical Center Groningen 4 34 110 461 46 0 655
Breakthrough Genomics, Breakthrough Genomics 0 0 63 319 211 0 593
Genome-Nilou Lab 0 0 0 0 545 0 545
Genome Diagnostics Laboratory, University Medical Center Utrecht 20 21 69 221 107 0 438
Laboratory of Diagnostic Genome Analysis, Leiden University Medical Center (LUMC) 1 2 51 317 25 0 396
Genetic Services Laboratory, University of Chicago 8 3 133 119 129 0 392
Dr. Peter K. Rogan Lab, Western University 0 0 0 0 0 285 285
Cardiogenetics and Myogenetics Molecular and Cellular Functional Unit, Aphp Sorbonne University-Hopital Pitie Salpetriere 12 242 16 0 0 0 270
Center for Advanced Laboratory Medicine, UC San Diego Health, University of California San Diego 6 3 40 98 74 0 221
Department of Pathology and Laboratory Medicine, Sinai Health System 0 10 149 4 5 0 168
AiLife Diagnostics, AiLife Diagnostics 10 43 103 0 0 0 156
Cardiovascular Biomedical Research Unit, Royal Brompton & Harefield NHS Foundation Trust 0 93 59 0 0 0 149
Baylor Genetics 11 14 122 0 0 0 145
Victorian Clinical Genetics Services, Murdoch Childrens Research Institute 18 59 37 2 0 0 116
Genetics and Genomics Program, Sidra Medicine 1 4 62 42 0 0 108
Blueprint Genetics 6 54 33 7 0 0 100
New York Genome Center 2 8 86 0 0 0 96
Juno Genomics, Hangzhou Juno Genomics, Inc 15 68 3 0 0 0 86
Genomic Medicine Center of Excellence, King Faisal Specialist Hospital and Research Centre 10 27 34 7 0 0 77
Clinical Genetics Laboratory, Skane University Hospital Lund 16 27 25 0 0 0 68
Practice for Gait Abnormalities, David Pomarino, Competency Network Toe Walking C/o Practice Pomarino 1 57 6 0 0 0 64
Cambridge Genomics Laboratory, East Genomic Laboratory Hub, NHS Genomic Medicine Service 2 0 37 14 2 0 54
3billion 17 25 9 0 0 0 51
Laboratory of Genetics, Children's Clinical University Hospital Latvia 6 5 1 29 6 0 47
Myofin, Folkhalsan Research Center 25 1 19 0 0 0 45
Centre for Mendelian Genomics, University Medical Centre Ljubljana 5 6 25 6 2 0 42
Broad Center for Mendelian Genomics, Broad Institute of MIT and Harvard 19 14 6 0 0 0 39
Stanford Center for Inherited Cardiovascular Disease, Stanford University 0 14 22 0 0 0 36
Research Unit of Cardiovascular and Metabolic Disease, Inserm 0 31 0 0 0 0 31
GenomeConnect, ClinGen 0 0 0 0 0 30 30
Lildballe Lab, Aarhus University Hospital 6 24 0 0 0 0 30
Center for Human Genetics, University of Leuven 3 25 1 0 0 0 29
Clinical Genomics Laboratory, Washington University in St. Louis 0 7 22 0 0 0 29
Mendelics 18 0 4 2 4 0 28
Molecular Genetics, Royal Melbourne Hospital 5 7 4 9 3 0 28
Institute of Human Genetics, University of Leipzig Medical Center 11 9 7 0 0 0 27
Institute of Human Genetics, University of Wuerzburg 3 8 2 3 1 8 25
Laboratorio de Genetica e Diagnostico Molecular, Hospital Israelita Albert Einstein 1 7 14 3 0 0 25
Genome Diagnostics Laboratory, Amsterdam University Medical Center 0 0 24 0 0 0 24
Institut für Laboratoriums- und Transfusionsmedizin, Herz- und Diabeteszentrum Nordrhein-Westfalen 0 8 15 1 0 0 24
KardioGenetik, Herz- und Diabeteszentrum NRW 0 18 6 0 0 0 24
Dasa 19 3 0 1 0 0 23
deCODE genetics, Amgen 2 21 0 0 0 0 23
Genomic Research Center, Shahid Beheshti University of Medical Sciences 5 2 15 0 0 0 22
Institute of Immunology and Genetics Kaiserslautern 13 5 2 0 0 0 20
KTest Genetics, KTest 14 5 0 0 0 0 19
Neuberg Centre For Genomic Medicine, NCGM 2 3 12 1 0 0 18
GeneReviews 10 0 1 0 0 6 17
Center for Genetic Medicine Research, Children's National Medical Center 0 5 11 0 0 0 16
Clinical Genomics Laboratory, Stanford Medicine 1 7 8 0 0 0 16
OMIM 16 0 0 0 0 0 16
Kariminejad - Najmabadi Pathology & Genetics Center 1 6 8 0 0 0 15
Center for Pediatric Genomic Medicine, Children's Mercy Hospital and Clinics 1 0 6 6 1 0 14
Human Genetics Bochum, Ruhr University Bochum 2 11 1 0 0 0 14
Molecular Genetics, Labor Dr. Heidrich & Kollegen MVZ GmbH 0 1 10 3 0 0 14
GenomeConnect - Invitae Patient Insights Network 0 0 0 0 0 13 13
MVZ Martinsried, Medicover Genetics 1 11 1 0 0 0 13
Muscle and Diseases Team, Institut de Génétique et Biologie Moléculaire et Cellulaire 0 11 2 0 0 0 13
Rady Children's Institute for Genomic Medicine, Rady Children's Hospital San Diego 3 10 0 0 0 0 13
Petrovsky National Research Centre of Surgery, The Federal Agency for Scientific Organizations 0 9 3 0 0 0 12
Phosphorus, Inc. 0 0 10 0 2 0 12
Genomic Diagnostic Laboratory, Division of Genomic Diagnostics, Children's Hospital of Philadelphia 0 0 10 0 1 0 11
Institute of Medical Genetics and Applied Genomics, University Hospital Tübingen 4 6 1 0 0 0 11
Daryl Scott Lab, Baylor College of Medicine 3 0 7 0 0 0 10
Dubai Health Genomic Medicine Center, Dubai Health 0 1 5 2 2 0 10
MVZ Medizinische Genetik Mainz 0 8 2 0 0 0 10
Diagnostics Services (NGS), CSIR - Centre For Cellular And Molecular Biology 0 7 2 0 0 0 9
Greenwood Genetic Center Diagnostic Laboratories, Greenwood Genetic Center 2 2 5 0 0 0 9
Institute of Human Genetics Munich, TUM University Hospital 3 6 0 0 0 0 9
Klaassen Lab, Charite University Medicine Berlin 0 6 2 0 0 0 8
Knight Diagnostic Laboratories, Oregon Health and Sciences University 1 0 6 1 0 0 8
Laboratory of Medical Genetics Unit, Bambino Gesù Children's Hospital 2 6 0 0 0 0 8
MGZ Medical Genetics Center 2 2 4 0 0 0 8
Molecular Genetics Laboratory, Motol Hospital 4 4 0 0 0 0 8
Solve-RD Consortium 1 7 0 0 0 0 8
CENTOGENE GmbH and LLC - Guiding Precision Medicine 0 3 4 0 0 0 7
Clinical Genetics Laboratory, Region Ostergotland 1 6 0 0 0 0 7
Clinical Genetics Laboratory, University Hospital Schleswig-Holstein 2 4 1 0 0 0 7
Department of Human Genetics, Hannover Medical School 0 3 4 0 0 0 7
Institute of Human Genetics, Cologne University 0 5 1 1 0 0 7
NeuroMeGen, Hospital Clinico Santiago de Compostela 0 7 0 0 0 0 7
Undiagnosed Diseases Network, NIH 3 3 0 1 0 0 7
Arcensus 1 3 2 0 0 0 6
Biochemical Molecular Genetic Laboratory, King Abdulaziz Medical City 1 3 2 0 0 0 6
Clinical Center for Gene Diagnosis and Therapy, Department of Cardiovascular Surgery, The Second Xiangya Hospital of Central South University 0 0 6 0 0 0 6
Clinical Molecular Genetics Laboratory, Johns Hopkins All Children's Hospital 0 0 4 2 0 0 6
IMHOTEP Cardiovascular Genetics Laboratory, University of Cape Town 0 0 6 0 0 0 6
Institute for Medical Genetics and Human Genetics, Charité - Universitätsmedizin Berlin 0 2 4 0 0 0 6
Institute of Human Genetics, Heidelberg University 1 5 0 0 0 0 6
Johns Hopkins Genomics, Johns Hopkins University 1 3 2 0 0 0 6
Loeys Lab, Universiteit Antwerpen 6 0 0 0 0 0 6
Suma Genomics 3 0 3 0 0 0 6
Agnes Ginges Centre for Molecular Cardiology, Centenary Institute 0 1 3 1 0 0 5
CGC Genetics, Unilabs 0 4 1 0 0 0 5
Clinical Genetics and Genomics, Karolinska University Hospital 1 4 0 0 0 0 5
Cytogenetics- Mohapatra Lab, Banaras Hindu University 0 5 0 0 0 0 5
Equipe Genetique des Anomalies du Developpement, Université de Bourgogne 0 2 3 0 0 0 5
Genetics and Molecular Pathology, SA Pathology 0 5 0 0 0 0 5
Genomic Medicine Lab, University of California San Francisco 0 2 3 0 0 0 5
Hadassah Hebrew University Medical Center 5 0 0 0 0 0 5
Robert's Program, Boston Children's Hospital 2 0 3 0 0 0 5
Zotz-Klimas Genetics Lab, MVZ Zotz Klimas 0 0 5 0 0 0 5
Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital 0 1 2 1 0 0 4
Center of Excellence for Medical Genomics, Chulalongkorn University 2 0 2 0 0 0 4
Center of Genomic medicine, Geneva, University Hospital of Geneva 4 0 0 0 0 0 4
Diagnostics Centre, Carl Von Ossietzky University Oldenburg 1 3 0 0 0 0 4
Genomics England Pilot Project, Genomics England 0 4 0 0 0 0 4
Génétique et pathophysiologie de maladies neurodéveloppementales et épileptogènes, Institut de génétique et de biologie moléculaire et cellulaire 0 0 0 0 4 0 4
Lupski Lab, Baylor-Hopkins CMG, Baylor College of Medicine 2 2 0 0 0 0 4
North West Genomic Laboratory Hub, Manchester University NHS Foundation Trust 0 4 0 0 0 0 4
OLLIN Analises Genomicas, OLLIN 2 1 1 0 0 0 4
Pediatric Department, Peking University First Hospital 3 1 0 0 0 0 4
Bioscientia Institut fuer Medizinische Diagnostik GmbH, Sonic Healthcare 0 0 3 0 0 0 3
Division of Human Genetics, Children's Hospital of Philadelphia 0 1 2 0 0 0 3
First Genomix Gene Laboratory, Genetic Diagnostics Department 0 3 0 0 0 0 3
Foundation for Research in Genetics and Endocrinology, FRIGE's Institute of Human Genetics 0 2 1 0 0 0 3
HudsonAlpha Institute for Biotechnology, HudsonAlpha Institute for Biotechnology 2 1 0 0 0 0 3
Human Genome Sequencing Center Clinical Lab, Baylor College of Medicine 1 2 0 0 0 0 3
Institute of Human Genetics, Clinical Exome/Genome Diagnostics Group, University Hospital Bonn 0 2 1 0 0 0 3
Intergen Genetics and Rare Diseases Diagnosis Center 0 0 2 1 0 0 3
Laboratory of Medical Genetics, National & Kapodistrian University of Athens 1 1 1 0 0 0 3
MVZ Praenatalmedizin und Genetik Nuernberg 0 2 1 0 0 0 3
University of Washington Center for Mendelian Genomics, University of Washington 0 1 2 0 0 0 3
Center for Genomics, Ann and Robert H. Lurie Children's Hospital of Chicago 2 0 0 0 0 0 2
DECIPHER, Wellcome Sanger Institute 0 0 0 0 0 2 2
Department of Clinical Genetics, Nationwide Children's Hospital 0 1 1 0 0 0 2
Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University 0 0 2 0 0 0 2
Department of Rehabilitation Medicine, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea 2 0 0 0 0 0 2
Dr. Alfred Bastarche Laboratory, Dr. Georges L. Dumont University Hospital Centre 0 1 1 0 0 0 2
Genetics and Personalized Medicine Clinic, Tartu University Hospital 1 1 0 0 0 0 2
GenomeConnect - Brain Gene Registry 0 0 0 0 0 2 2
Genomics, Clalit Research Institute, Clalit Health Care 0 2 0 0 0 0 2
Genotypic Technology Pvt Ltd 0 2 0 0 0 0 2
Human Development and Health, University of Southampton 0 0 0 0 0 2 2
Imagene.me medical diagnostic laboratory, IMAGENE.ME SA 2 0 0 0 0 0 2
Institute of Human Genetics, FAU Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg 0 2 0 0 0 0 2
Laboratorio Biología Molecular, Sanatorio Americano 0 2 0 0 0 0 2
Medical Genetics Center, Maternal and Child Health Hospital of Hubei Province 2 0 0 0 0 0 2
Medical and Scientific Branch, Hong Kong Genome Institute 1 1 0 0 0 0 2
Pediatric/Medical Genetics, Ministry of Health, Qatif Central Hospital 0 0 2 0 0 0 2
Pittsburgh Clinical Genomics Laboratory, University of Pittsburgh Medical Center 0 0 2 0 0 0 2
Rajaie Cardiovascular, Medical and Research Center, Iran University of Medical Sciences 0 2 0 0 0 0 2
Regional Center For Medical Genetics Timis, Louis Turcanu Emergency Hospital for Children Timisoara 0 1 1 0 0 0 2
Service de Génétique Moléculaire, Hôpital Robert Debré 0 0 2 0 0 0 2
Variantyx, Inc. 1 1 0 0 0 0 2
Breda Genetics srl, Breda Genetics srl 0 0 1 0 0 0 1
CUBI - Core Unit Bioinformatics, Berlin Institute of Health 0 0 1 0 0 0 1
Center for Human Genetics and Genomic Medicine, Uniklinik Rwth Aachen 0 0 1 0 0 0 1
Center for Medical Genetics Ghent, University of Ghent 0 1 0 0 0 0 1
Center for Personalized Medicine, Children's Hospital Los Angeles 0 0 1 0 0 0 1
Centre de Biologie Pathologie Génétique, Centre Hospitalier Universitaire de Lille 0 1 0 0 0 0 1
Centre for Clinical Genetics and Genomic Diagnostics, Zealand University Hospital 0 0 1 0 0 0 1
Clinical Biomedical Laboratory, Shriners Hospital For Children - Canada 0 1 0 0 0 0 1
Clinical Laboratory Sciences Program (CLSP), King Saud bin Abdulaziz University for Health Sciences (KSAU-HS) 1 0 0 0 0 0 1
Clinical Research Group, BGI genomics 0 1 0 0 0 0 1
DECIPHERD-UDD, Universidad del Desarrollo 0 0 1 0 0 0 1
Department of Clinical Pathology, School of Medicine, Fujita Health University 0 0 0 1 0 0 1
Department of Genetics and Molecular Biology, Isfahan University of Medical Sciences 1 0 0 0 0 0 1
Department of Legal Medicine, University of Toyama 1 0 0 0 0 0 1
Department of Medical Genetics, National Institute of Health 1 0 0 0 0 0 1
Department of Obstetrics and Gynecology, Women and Children’s Hospital Affiliated to Ningbo University 0 1 0 0 0 0 1
Department of Pediatrics, Division of Medical Genetics, Faculty of Medicine Ramathibodi Hospital, Mahidol University 0 0 1 0 0 0 1
Department of Psychiatry, The University of Hong Kong 0 0 1 0 0 0 1
Diagnostics Division, CENTRE FOR DNA FINGERPRINTING AND DIAGNOSTICS 0 0 1 0 0 0 1
Division Of Personalized Genomic Medicine, Columbia University Irving Medical Center 0 1 0 0 0 0 1
Genatak 0 1 0 0 0 0 1
Genesolutions, Medical Genetics Institutes, Ho Chi Minh City, Vietnam 1 0 0 0 0 0 1
Genetics Department, Catlab 0 1 0 0 0 0 1
Genetics Department, Hospital De La Santa Creu I Sant Pau 0 1 0 0 0 0 1
Grupo de Genetica Humana, Facultad de Medicina - Universidad de La Sabana 1 0 0 0 0 0 1
Heart Center, Academic Medical Center Amsterdam 0 1 0 0 0 0 1
ICMR Centre for Advanced Research and Excellence in Heart Failure, Sree Chitra Tirunal Institute for Medical Sciences & Technology, KERALA, INDIA 0 1 0 0 0 0 1
Inheritance Genetic Center 0 1 0 0 0 0 1
Institute for Clinical Genetics, University Hospital TU Dresden, University Hospital TU Dresden 1 0 0 0 0 0 1
Institute of Clinical Chemistry and Institute of Clinical Molecular Biology, University Hospital Schleswig-Holstein, Campus Kiel 1 0 0 0 0 0 1
Institute of Human Genetics, Medical University Innsbruck 1 0 0 0 0 0 1
Institute of Human Genetics, University of Goettingen 0 1 0 0 0 0 1
Juha Muilu Group; Institute for Molecular Medicine Finland (FIMM) 0 1 0 0 0 0 1
Laboratory of Cardiovascular Genetics, IRCCS Istituto Auxologico Italiano 0 1 0 0 0 0 1
Laboratory of Functional Genomics, Research Centre for Medical Genetics 0 1 0 0 0 0 1
Lifecell International Pvt. Ltd 1 0 0 0 0 0 1
Neurogenetics Research Program, University of Adelaide 0 1 0 0 0 0 1
Neurogenetics, Research Centre for Medical Genetics 1 0 0 0 0 0 1
Provincial Medical Genetics Program of British Columbia, University of British Columbia 1 0 0 0 0 0 1
Royal Brompton Clinical Genetics And Genomics Laboratory, NHS South East Genomic Laboratory Hub 0 1 0 0 0 0 1
Service of Pediatric Gastrohepatology and Metabolic Diseases, University of Medicine of Tirana 0 1 0 0 0 0 1
Servicio Canario de Salud, Hospital Universitario Nuestra Sra. de Candelaria 0 1 0 0 0 0 1
Soonchunhyang University Bucheon Hospital, Soonchunhyang University Medical Center 0 0 1 0 0 0 1

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