ClinVar Miner

Variants in gene MYOM1

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Minimum conflict level:
Gene type:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign not provided total
0 3 1271 766 226 35 2190

Condition and significance breakdown #

Total conditions: 32
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Condition likely pathogenic uncertain significance likely benign benign not provided total
Hypertrophic cardiomyopathy 1 941 566 96 0 1601
not specified 0 634 355 53 0 1018
not provided 0 27 46 172 0 241
MYOM1-related disorder 0 4 33 19 1 57
Cardiovascular phenotype 0 8 3 16 0 27
Hepatocellular carcinoma 0 0 0 0 7 7
Malignant tumor of esophagus 0 0 0 0 6 6
Primary familial hypertrophic cardiomyopathy 0 5 1 0 0 6
Ovarian serous cystadenocarcinoma 0 0 0 0 5 5
Cervical cancer 0 0 0 0 4 4
Sarcoma 0 0 0 0 4 4
Thyroid cancer, nonmedullary, 1 0 0 0 0 4 4
Uterine corpus endometrial carcinoma 0 0 0 0 4 4
Thymoma 0 0 0 0 3 3
Cholangiocarcinoma 0 0 0 0 2 2
Gastric cancer 0 0 0 0 2 2
MYOM1-related non-immune fetal hydrops 0 2 0 0 0 2
Papillary renal cell carcinoma type 1 0 0 0 0 2 2
Uterine carcinosarcoma 0 0 0 0 2 2
Adrenocortical carcinoma, hereditary 0 0 0 0 1 1
Arrhythmogenic right ventricular cardiomyopathy 0 1 0 0 0 1
Cardiac arrest 0 1 0 0 0 1
Cardiomyopathy 0 1 0 0 0 1
Colorectal cancer 0 0 0 0 1 1
Glioma susceptibility 1 0 0 0 0 1 1
Hypertrophic cardiomyopathy 9 0 1 0 0 0 1
Hypoglycemia; Abnormality of the liver 1 0 0 0 0 1
Malignant lymphoma, large B-cell, diffuse 0 0 0 0 1 1
Non-immune hydrops fetalis 1 0 0 0 0 1
Primary dilated cardiomyopathy 0 1 0 0 0 1
Sudden cardiac death 0 1 0 0 0 1
Uveal melanoma 0 0 0 0 1 1

Submitter and significance breakdown #

Total submitters: 24
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Submitter likely pathogenic uncertain significance likely benign benign not provided total
Labcorp Genetics (formerly Invitae), Labcorp 0 938 568 96 0 1602
Ambry Genetics 0 628 337 21 0 986
GeneDx 0 0 19 152 0 171
Breakthrough Genomics, Breakthrough Genomics 0 7 23 82 0 112
Laboratory for Molecular Medicine, Mass General Brigham Personalized Medicine 0 23 31 52 0 106
PreventionGenetics, part of Exact Sciences 0 4 33 19 0 56
Dr. Peter K. Rogan Lab, Western University 0 0 0 0 34 34
Blueprint Genetics 0 8 1 0 0 9
Center for Genomics, Ann and Robert H. Lurie Children's Hospital of Chicago 0 8 0 0 0 8
CeGaT Center for Human Genetics Tuebingen 0 0 6 1 0 7
Stanford Center for Inherited Cardiovascular Disease, Stanford University 0 5 0 0 0 5
Revvity Omics, Revvity 0 4 0 0 0 4
Victorian Clinical Genetics Services, Murdoch Childrens Research Institute 0 3 1 0 0 4
Fulgent Genetics, Fulgent Genetics 0 3 0 0 0 3
AiLife Diagnostics, AiLife Diagnostics 0 2 0 0 0 2
Baylor Genetics 0 2 0 0 0 2
Clinical Genomics Laboratory, Stanford Medicine 0 2 0 0 0 2
Clinical Genomics Laboratory, Washington University in St. Louis 0 2 0 0 0 2
Agnes Ginges Centre for Molecular Cardiology, Centenary Institute 0 1 0 0 0 1
Bionano Laboratories 0 1 0 0 0 1
GenomeConnect, ClinGen 0 0 0 0 1 1
Genomic Medicine Center of Excellence, King Faisal Specialist Hospital and Research Centre 1 0 0 0 0 1
Hadassah Hebrew University Medical Center 1 0 0 0 0 1
Strand Center for Genomics and Personalized Medicine, Strand Life Sciences Pvt Ltd 1 0 0 0 0 1

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