ClinVar Miner

Variants in gene ANKRD26

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Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign not provided total
12 20 1920 870 202 32 2826

Condition and significance breakdown #

Total conditions: 28
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Condition pathogenic likely pathogenic uncertain significance likely benign benign not provided total
Inborn genetic diseases 0 0 1389 587 0 0 1976
not provided 9 8 885 360 176 1 1366
Thrombocytopenia 2 10 16 132 28 89 1 249
not specified 0 0 75 32 47 0 148
ANKRD26-related disorder 1 1 38 49 7 0 96
Thrombocytopenia 3 9 1 0 0 0 13
Ovarian serous cystadenocarcinoma 0 0 0 0 0 11 11
Malignant tumor of esophagus 0 0 0 0 0 7 7
Gastric cancer 0 0 0 0 0 6 6
Acute myeloid leukemia 0 0 0 0 0 5 5
Sarcoma 0 0 0 0 0 4 4
Uterine carcinosarcoma 0 0 0 0 0 4 4
Uterine corpus endometrial carcinoma 0 0 0 0 0 4 4
Lung cancer 0 0 0 0 0 3 3
Thymoma 0 0 0 0 0 3 3
Thyroid cancer, nonmedullary, 1 0 0 0 0 0 3 3
Uveal melanoma 0 0 0 0 0 3 3
Cervical cancer 0 0 0 0 0 2 2
Cholangiocarcinoma 0 0 0 0 0 2 2
Colon adenocarcinoma 0 0 0 0 0 2 2
Hereditary cancer-predisposing syndrome 0 1 1 0 0 0 2
Malignant lymphoma, large B-cell, diffuse 0 0 0 0 0 2 2
Abnormal bleeding; Thrombocytopenia 0 0 1 0 0 0 1
Breast ductal adenocarcinoma 0 0 1 0 0 0 1
Inherited bleeding disorder, platelet-type 1 0 0 0 0 0 1
Malignant tumor of urinary bladder 0 0 0 0 0 1 1
Melanoma 0 0 0 0 0 1 1
Squamous cell lung carcinoma 0 0 0 0 0 1 1

Submitter and significance breakdown #

Total submitters: 51
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign not provided total
Ambry Genetics 0 0 1389 587 0 0 1976
Labcorp Genetics (formerly Invitae), Labcorp 9 0 672 283 85 0 1049
GeneDx 2 2 363 58 102 0 527
PreventionGenetics, part of Exact Sciences 1 1 38 51 25 0 116
Illumina Laboratory Services, Illumina 0 0 41 9 65 0 115
Genetic Services Laboratory, University of Chicago 0 2 61 18 16 0 97
Mayo Clinic Laboratories, Mayo Clinic 3 6 31 26 27 0 93
Breakthrough Genomics, Breakthrough Genomics 0 0 3 22 64 0 89
Genome-Nilou Lab 0 0 0 0 62 0 62
St. Jude Molecular Pathology, St. Jude Children's Research Hospital 0 0 58 0 0 0 58
ARUP Laboratories, Molecular Genetics and Genomics, ARUP Laboratories 0 0 6 14 28 0 48
Dr. Peter K. Rogan Lab, Western University 0 0 0 0 0 30 30
CeGaT Center for Human Genetics Tuebingen 2 2 3 13 7 0 27
Women's Health and Genetics/Laboratory Corporation of America, LabCorp 3 0 16 4 0 0 23
ISTH-SSC Genomics in Thrombosis and Hemostasis, KU Leuven, Center for Molecular and Vascular Biology 4 10 1 0 0 0 15
Laboratory of Genetics, Children's Clinical University Hospital Latvia 0 0 1 6 7 0 14
NIHR Bioresource Rare Diseases, University of Cambridge 3 9 1 0 0 0 13
Fulgent Genetics, Fulgent Genetics 1 1 7 2 0 0 11
Revvity Omics, Revvity 0 0 9 0 0 0 9
Department of Pathology and Laboratory Medicine, Sinai Health System 0 0 4 4 0 0 8
Zotz-Klimas Genetics Lab, MVZ Zotz Klimas 2 0 5 0 0 0 7
Baylor Genetics 0 0 5 0 0 0 5
Genetics and Molecular Pathology, SA Pathology 0 2 1 1 1 0 5
Genomic Medicine Center of Excellence, King Faisal Specialist Hospital and Research Centre 0 2 1 1 1 0 5
Victorian Clinical Genetics Services, Murdoch Childrens Research Institute 3 0 2 0 0 0 5
Genome Diagnostics Laboratory, University Medical Center Utrecht 0 0 0 3 1 0 4
Laboratory of Diagnostic Genome Analysis, Leiden University Medical Center (LUMC) 0 0 0 3 1 0 4
Clinical Genetics DNA and cytogenetics Diagnostics Lab, Erasmus MC, Erasmus Medical Center 0 0 0 3 0 0 3
OMIM 3 0 0 0 0 0 3
Biochemical Molecular Genetic Laboratory, King Abdulaziz Medical City 0 1 1 0 0 0 2
Center for Genomics, Ann and Robert H. Lurie Children's Hospital of Chicago 0 0 1 1 0 0 2
Johns Hopkins Genomics, Johns Hopkins University 0 1 0 1 0 0 2
Laboratorio de Genetica e Diagnostico Molecular, Hospital Israelita Albert Einstein 1 0 1 0 0 0 2
Mendelics 0 0 1 0 1 0 2
Molecular Pathology, Peter Maccallum Cancer Centre 0 1 1 0 0 0 2
Neuberg Centre For Genomic Medicine, NCGM 0 0 2 0 0 0 2
Birmingham Platelet Group; University of Birmingham 0 0 1 0 0 0 1
Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital 1 0 0 0 0 0 1
Center of Genomic medicine, Geneva, University Hospital of Geneva 0 1 0 0 0 0 1
Centre for Mendelian Genomics, University Medical Centre Ljubljana 0 0 1 0 0 0 1
Clinical Genetics Laboratory, Skane University Hospital Lund 0 0 1 0 0 0 1
Dr.Nikuei Genetic Center 0 0 0 1 0 0 1
Dubai Health Genomic Medicine Center, Dubai Health 0 0 1 0 0 0 1
Genome Diagnostics Laboratory, Amsterdam University Medical Center 0 0 0 0 1 0 1
GenomeConnect - Invitae Patient Insights Network 0 0 0 0 0 1 1
GenomeConnect, ClinGen 0 0 0 0 0 1 1
Godley laboratory, The University of Chicago 1 0 0 0 0 0 1
Ledgerwood and Morison Labs, University of Otago 0 1 0 0 0 0 1
Next Generation Diagnostics, Novartis Institutes for BioMedical Research, Inc. 0 0 1 0 0 0 1
Pittsburgh Clinical Genomics Laboratory, University of Pittsburgh Medical Center 0 0 1 0 0 0 1
Randwick Genomics Laboratory, Prince of Wales Hospital Sydney, Australia, New South Wales Health Pathology 0 1 0 0 0 0 1

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