If a variant has more than one submission, it may be counted in more than one significance column. If this is the
case, the total number of variants will be less than the sum of the other cells.
| pathogenic |
likely pathogenic |
uncertain significance |
likely benign |
benign |
not provided |
total |
|
12
|
13
|
541
|
215
|
1391
|
4
|
2163
|
Gene and significance breakdown #
Total genes and gene combinations: 21
| Gene or gene combination |
pathogenic |
likely pathogenic |
uncertain significance |
likely benign |
benign |
not provided |
total |
|
TTN
|
12
|
11
|
480
|
195
|
1212
|
4
|
1905
|
|
LOC126806425, TTN
|
0 |
1
|
7
|
3
|
18
|
0 |
28
|
|
LOC101927055, TTN
|
0 |
1
|
4
|
1
|
20
|
0 |
26
|
|
LOC126806430, TTN
|
0 |
0 |
6
|
4
|
16
|
0 |
26
|
|
LOC126806422, TTN
|
0 |
0 |
5
|
1
|
15
|
0 |
19
|
|
LOC126806423, TTN
|
0 |
0 |
3
|
2
|
11
|
0 |
16
|
|
LOC126806421, TTN
|
0 |
0 |
3
|
0 |
12
|
0 |
15
|
|
LOC126806424, TTN
|
0 |
0 |
2
|
1
|
12
|
0 |
15
|
|
LOC126806427, TTN
|
0 |
0 |
2
|
0 |
13
|
0 |
15
|
|
LOC126806420, TTN
|
0 |
0 |
2
|
2
|
10
|
0 |
14
|
|
LOC126806431, TTN
|
0 |
0 |
5
|
0 |
9
|
0 |
14
|
|
LOC126806426, TTN
|
0 |
0 |
6
|
1
|
6
|
0 |
13
|
|
LOC126806428, TTN
|
0 |
0 |
2
|
0 |
10
|
0 |
12
|
|
LOC126806429, TTN
|
0 |
0 |
1
|
1
|
10
|
0 |
12
|
|
LOC129935183, TTN
|
0 |
0 |
3
|
2
|
7
|
0 |
12
|
|
LOC126806433, TTN
|
0 |
0 |
6
|
0 |
4
|
0 |
10
|
|
LOC129935184, TTN
|
0 |
0 |
2
|
1
|
4
|
0 |
6
|
|
LOC129935182, TTN
|
0 |
0 |
1
|
0 |
1
|
0 |
2
|
|
LOC126806432, TTN
|
0 |
0 |
1
|
0 |
0 |
0 |
1
|
|
LOC129935185, TTN
|
0 |
0 |
0 |
0 |
1
|
0 |
1
|
|
LOC129935186, TTN
|
0 |
0 |
0 |
1
|
0 |
0 |
1
|
Submitter and significance breakdown #
| Submitter |
pathogenic |
likely pathogenic |
uncertain significance |
likely benign |
benign |
not provided |
total |
|
Illumina Laboratory Services, Illumina
|
0 |
1
|
478
|
214
|
1079
|
0 |
1772
|
|
Genome-Nilou Lab
|
0 |
0 |
0 |
0 |
635
|
0 |
635
|
|
Baylor Genetics
|
1
|
6
|
51
|
0 |
0 |
0 |
58
|
|
GeneReviews
|
5
|
0 |
1
|
0 |
0 |
2
|
8
|
|
Neuberg Centre For Genomic Medicine, NCGM
|
2
|
0 |
2
|
0 |
0 |
0 |
4
|
|
3billion
|
1
|
1
|
0 |
0 |
0 |
0 |
2
|
|
CENTOGENE GmbH and LLC - Guiding Precision Medicine
|
0 |
1
|
1
|
0 |
0 |
0 |
2
|
|
GenomeConnect, ClinGen
|
0 |
0 |
0 |
0 |
0 |
2
|
2
|
|
Intergen Genetics and Rare Diseases Diagnosis Center
|
0 |
0 |
1
|
1
|
0 |
0 |
2
|
|
Johns Hopkins Genomics, Johns Hopkins University
|
1
|
1
|
0 |
0 |
0 |
0 |
2
|
|
NeuroMeGen, Hospital Clinico Santiago de Compostela
|
0 |
2
|
0 |
0 |
0 |
0 |
2
|
|
OMIM
|
2
|
0 |
0 |
0 |
0 |
0 |
2
|
|
Broad Center for Mendelian Genomics, Broad Institute of MIT and Harvard
|
0 |
0 |
1
|
0 |
0 |
0 |
1
|
|
Genomics England Pilot Project, Genomics England
|
0 |
1
|
0 |
0 |
0 |
0 |
1
|
|
Institute of Human Genetics, University of Leipzig Medical Center
|
0 |
0 |
1
|
0 |
0 |
0 |
1
|
|
Institute of Immunology and Genetics Kaiserslautern
|
1
|
0 |
0 |
0 |
0 |
0 |
1
|
|
Juno Genomics, Hangzhou Juno Genomics, Inc
|
0 |
0 |
1
|
0 |
0 |
0 |
1
|
|
MGZ Medical Genetics Center
|
0 |
0 |
1
|
0 |
0 |
0 |
1
|
|
OLLIN Analises Genomicas, OLLIN
|
0 |
0 |
1
|
0 |
0 |
0 |
1
|
|
Pittsburgh Clinical Genomics Laboratory, University of Pittsburgh Medical Center
|
0 |
0 |
1
|
0 |
0 |
0 |
1
|
|
Victorian Clinical Genetics Services, Murdoch Childrens Research Institute
|
1
|
0 |
0 |
0 |
0 |
0 |
1
|
|
Women's Health and Genetics/Laboratory Corporation of America, LabCorp
|
1
|
0 |
0 |
0 |
0 |
0 |
1
|
|
Zotz-Klimas Genetics Lab, MVZ Zotz Klimas
|
0 |
0 |
1
|
0 |
0 |
0 |
1
|
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genetics professional. Individuals should not change their
health behavior solely on the basis of information contained on
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If you have questions about the information contained on this
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