ClinVar Miner

Variants studied for Immunodeficiency 104

Coded as:
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign not provided total
74 39 535 941 105 5 1651

Gene and significance breakdown #

Total genes and gene combinations: 6
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Gene or gene combination pathogenic likely pathogenic uncertain significance likely benign benign not provided total
PTPRC 16 17 325 700 47 5 1101
IL7R 57 22 209 241 55 0 545
RAG1 0 0 0 0 2 0 2
CD3D 0 0 0 0 1 0 1
IL7R, LOC129993794 1 0 0 0 0 0 1
RAG2 0 0 1 0 0 0 1

Submitter and significance breakdown #

Total submitters: 29
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign not provided total
Labcorp Genetics (formerly Invitae), Labcorp 62 22 456 934 74 0 1548
Illumina Laboratory Services, Illumina 0 0 61 7 38 0 106
ClinGen Severe Combined Immunodeficiency Variant Curation Expert Panel, ClinGen 7 5 9 8 8 0 37
Fulgent Genetics, Fulgent Genetics 2 9 3 1 1 0 16
Center for Genomics, Ann and Robert H. Lurie Children's Hospital of Chicago 0 0 10 0 0 0 10
Baylor Genetics 1 0 7 0 0 0 8
OMIM 5 0 2 0 0 0 7
Genome-Nilou Lab 0 0 0 0 6 0 6
GenomeConnect - Invitae Patient Insights Network 0 0 0 0 0 5 5
Genomic Medicine Center of Excellence, King Faisal Specialist Hospital and Research Centre 1 0 3 0 0 0 4
GreenArray Genomic Research & Solutions of Accurate Diagnostic Private Limited 0 0 2 0 2 0 4
3billion 2 0 1 0 0 0 3
Laboratorio de Genetica e Diagnostico Molecular, Hospital Israelita Albert Einstein 2 1 0 0 0 0 3
Revvity Omics, Revvity 1 0 2 0 0 0 3
Department of Molecular and Human Genetics, Baylor College of Medicine 2 0 0 0 0 0 2
Laboratory of Pediatric Immunoinfectivology, Tor Vergata University 1 1 0 0 0 0 2
Lupski Lab, Baylor-Hopkins CMG, Baylor College of Medicine 2 0 0 0 0 0 2
Mendelics 0 0 0 0 2 0 2
Neuberg Centre For Genomic Medicine, NCGM 0 1 1 0 0 0 2
Next Generation Genetic Polyclinic 1 1 0 0 0 0 2
Rady Children's Institute for Genomic Medicine, Rady Children's Hospital San Diego 2 0 0 0 0 0 2
ARUP Laboratories, Molecular Genetics and Genomics, ARUP Laboratories 0 0 0 0 1 0 1
Center for Molecular Medicine, Children’s Hospital of Fudan University 1 0 0 0 0 0 1
Dasa 1 0 0 0 0 0 1
Diagnostic Laboratory, Department of Genetics, University Medical Center Groningen 0 0 0 0 1 0 1
Human Genetics Section, Sidra Medicine 1 0 0 0 0 0 1
Massaad Lab, American University of Beirut 1 0 0 0 0 0 1
Oxford Medical Genetics Laboratories, Oxford University Hospitals NHS Foundation Trust 1 0 0 0 0 0 1
Servicio inmunologia, Hospital 12 de Octubre 1 0 0 0 0 0 1

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