ClinVar Miner

Variants studied for Ehlers-Danlos syndrome, dermatosparaxis type

Coded as:
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign not provided total
71 81 615 1016 104 11 1774

Gene and significance breakdown #

Total genes and gene combinations: 5
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Gene or gene combination pathogenic likely pathogenic uncertain significance likely benign benign not provided total
ADAMTS2 70 81 611 1016 104 11 1769
ADAMTS2, GRM6, ZNF354C, ZNF879 0 0 2 0 0 0 2
ADAMTS2, ARL10, B4GALT7, CANX, CBY3, CDHR2, CLK4, CLTB, COL23A1, CPLX2, DBN1, DDX41, DOK3, EIF4E1B, F12, FAF2, FAM153A, FAM153B, FAM193B, FGFR4, GPRIN1, GRK6, GRM6, HIGD2A, HK3, HNRNPAB, HNRNPH1, KIAA1191, LMAN2, LTC4S, MAML1, MGAT4B, MXD3, N4BP3, NHP2, NOP16, NSD1, PDLIM7, PFN3, PHYKPL, PRELID1, PROP1, PRR7, RAB24, RGS14, RMND5B, RNF44, RUFY1, SIMC1, SLC34A1, SNCB, SPATA31J1, SQSTM1, THOC3, TMED9, TSPAN17, UIMC1, UNC5A, ZFP2, ZNF346, ZNF354A, ZNF354B, ZNF354C, ZNF454, ZNF879 0 0 1 0 0 0 1
ADAMTS2, CANX, CBY3, HNRNPH1, LTC4S, MAML1, MGAT4B, RUFY1, SPATA31J1, SQSTM1 0 0 1 0 0 0 1
ADAMTS2, LOC112997581 1 0 0 0 0 0 1

Submitter and significance breakdown #

Total submitters: 25
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign not provided total
Labcorp Genetics (formerly Invitae), Labcorp 65 15 398 981 66 0 1525
Natera, Inc. 1 23 229 67 42 0 362
Illumina Laboratory Services, Illumina 1 1 119 18 48 0 187
Fulgent Genetics, Fulgent Genetics 1 15 24 4 1 0 45
Genome-Nilou Lab 0 0 0 0 29 0 29
Myriad Genetics, Inc. 1 22 0 0 0 0 23
Department of Pathology and Laboratory Medicine, Sinai Health System 0 2 8 0 0 0 10
Diagnostic Laboratory, Department of Genetics, University Medical Center Groningen 0 0 0 0 10 0 10
Genome Diagnostics Laboratory, Amsterdam University Medical Center 0 0 0 0 10 0 10
Revvity Omics, Revvity 1 1 6 0 0 0 8
Baylor Genetics 0 0 7 0 0 0 7
GenomeConnect - Invitae Patient Insights Network 0 0 0 0 0 7 7
Women's Health and Genetics/Laboratory Corporation of America, LabCorp 4 3 0 0 0 0 7
Counsyl 0 4 2 0 0 0 6
GenomeConnect, ClinGen 0 0 0 0 0 4 4
Center for Genomics, Ann and Robert H. Lurie Children's Hospital of Chicago 0 0 3 0 0 0 3
Mendelics 1 1 0 0 1 0 3
OMIM 3 0 0 0 0 0 3
Molecular Genetics, Royal Melbourne Hospital 0 0 1 0 1 0 2
Department of Genetics, Suzhou Beikang Medical Laboratory 0 1 0 0 0 0 1
Genomic Medicine Center of Excellence, King Faisal Specialist Hospital and Research Centre 0 1 0 0 0 0 1
MVZ Martinsried, Medicover Genetics 0 1 0 0 0 0 1
MVZ Medizinische Genetik Mainz 0 1 0 0 0 0 1
Pars Genome Lab 0 0 1 0 0 0 1
Victorian Clinical Genetics Services, Murdoch Childrens Research Institute 0 0 1 0 0 0 1

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