ClinVar Miner

Variants studied for Dilated cardiomyopathy 1G

Coded as:
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign not provided total
143 636 1540 297 128 2 2717

Gene and significance breakdown #

Total genes and gene combinations: 25
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Gene or gene combination pathogenic likely pathogenic uncertain significance likely benign benign not provided total
TTN 126 558 1378 250 109 2 2396
LOC126806423, TTN 4 15 11 3 1 0 34
LOC126806425, TTN 2 10 19 4 0 0 34
LOC101927055, TTN 0 5 12 8 5 0 30
LOC126806424, TTN 4 8 12 2 1 0 27
LOC126806422, TTN 0 8 12 4 0 0 24
LOC126806430, TTN 0 1 20 2 1 0 24
LOC126806421, TTN 1 7 11 1 1 0 21
LOC126806426, TTN 1 7 10 0 2 0 20
LOC126806427, TTN 0 3 6 7 1 0 16
LOC129935183, TTN 0 3 8 3 2 0 16
LOC126806420, TTN 0 4 6 3 0 0 13
LOC126806433, TTN 0 3 8 0 2 0 13
LOC126806428, TTN 1 0 6 2 3 0 12
LOC126806431, TTN 0 1 8 3 0 0 12
LOC126806429, TTN 0 0 5 3 0 0 8
LOC129935182, TTN 2 1 2 0 0 0 5
LOC129935184, TTN 0 0 4 1 0 0 5
CCDC141, TTN 1 0 0 0 0 0 1
CYLD, NOD2 0 0 1 0 0 0 1
DSP 0 1 0 0 0 0 1
LOC126806420, LOC126806421, LOC126806422, LOC126806423, LOC126806424, LOC129935181, LOC129935182, LOC129935183, LOC129935184, LOC129935185, LOC129935186, PLEKHA3, TTN 0 1 0 0 0 0 1
LOC126806422, LOC126806423, LOC126806424, LOC126806425, LOC126806426, LOC126806427, LOC129388955, TTN 1 0 0 0 0 0 1
LOC129935185, TTN 0 0 0 1 0 0 1
LOC129935186, TTN 0 0 1 0 0 0 1

Submitter and significance breakdown #

Total submitters: 91
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign not provided total
Illumina Laboratory Services, Illumina 1 13 1358 294 122 0 1788
Cardiogenetics and Myogenetics Molecular and Cellular Functional Unit, Aphp Sorbonne University-Hopital Pitie Salpetriere 13 268 19 0 0 0 300
Victorian Clinical Genetics Services, Murdoch Childrens Research Institute 12 67 28 1 0 0 108
Baylor Genetics 3 11 50 0 0 0 64
Genomic Medicine Center of Excellence, King Faisal Specialist Hospital and Research Centre 11 16 35 0 0 0 62
Juno Genomics, Hangzhou Juno Genomics, Inc 10 38 1 0 0 0 49
Labcorp Genetics (formerly Invitae), Labcorp 3 39 0 0 0 0 42
3billion 12 17 5 0 0 0 34
deCODE genetics, Amgen 2 24 0 0 0 0 26
Institute of Human Genetics, University of Leipzig Medical Center 13 9 3 0 0 0 25
KTest Genetics, KTest 18 6 0 0 0 0 24
KardioGenetik, Herz- und Diabeteszentrum NRW 0 19 5 0 0 0 24
Institute of Immunology and Genetics Kaiserslautern 9 5 0 0 0 0 14
MVZ Martinsried, Medicover Genetics 1 12 1 0 0 0 14
Mendelics 5 0 2 2 5 0 14
Clinical Genomics Laboratory, Washington University in St. Louis 0 6 7 0 0 0 13
Clinical Genomics Laboratory, Stanford Medicine 1 9 2 0 0 0 12
MVZ Medizinische Genetik Mainz 0 9 3 0 0 0 12
Phosphorus, Inc. 0 0 10 0 2 0 12
Human Genetics Bochum, Ruhr University Bochum 2 6 1 0 0 0 9
Department of Human Genetics, Hannover Medical School 1 4 3 0 0 0 8
Clinical Genetics Laboratory, University Hospital Schleswig-Holstein 3 4 0 0 0 0 7
Clinical Genetics Laboratory, Region Ostergotland 1 5 0 0 0 0 6
Clinical Genetics Laboratory, Skane University Hospital Lund 1 5 0 0 0 0 6
IMHOTEP Cardiovascular Genetics Laboratory, University of Cape Town 0 0 6 0 0 0 6
Molecular Genetics Laboratory, Motol Hospital 4 2 0 0 0 0 6
OMIM 6 0 0 0 0 0 6
Hadassah Hebrew University Medical Center 5 0 0 0 0 0 5
Institute of Human Genetics Munich, TUM University Hospital 2 3 0 0 0 0 5
Center of Genomic medicine, Geneva, University Hospital of Geneva 4 0 0 0 0 0 4
Genetics and Molecular Pathology, SA Pathology 0 3 1 0 0 0 4
Genomic Medicine Lab, University of California San Francisco 0 3 1 0 0 0 4
Genomics England Pilot Project, Genomics England 0 4 0 0 0 0 4
Institute of Human Genetics, Cologne University 0 3 1 0 0 0 4
Institute of Human Genetics, Heidelberg University 0 4 0 0 0 0 4
CGC Genetics, Unilabs 0 3 0 0 0 0 3
Clinical Genetics and Genomics, Karolinska University Hospital 0 3 0 0 0 0 3
Diagnostics Centre, Carl Von Ossietzky University Oldenburg 0 3 0 0 0 0 3
Genomic Research Center, Shahid Beheshti University of Medical Sciences 2 0 1 0 0 0 3
Human Genome Sequencing Center Clinical Lab, Baylor College of Medicine 1 2 0 0 0 0 3
Institute of Human Genetics, University of Wuerzburg 0 3 0 0 0 0 3
Knight Diagnostic Laboratories, Oregon Health and Sciences University 0 0 3 0 0 0 3
Laboratorio de Genetica e Diagnostico Molecular, Hospital Israelita Albert Einstein 0 1 2 0 0 0 3
MGZ Medical Genetics Center 1 1 1 0 0 0 3
MVZ Praenatalmedizin und Genetik Nuernberg 0 2 1 0 0 0 3
Neuberg Centre For Genomic Medicine, NCGM 0 1 2 0 0 0 3
OLLIN Analises Genomicas, OLLIN 2 1 0 0 0 0 3
Petrovsky National Research Centre of Surgery, The Federal Agency for Scientific Organizations 0 3 0 0 0 0 3
Genesolutions, Medical Genetics Institutes, Ho Chi Minh City, Vietnam 2 0 0 0 0 0 2
GenomeConnect, ClinGen 0 0 0 0 0 2 2
Genomics, Clalit Research Institute, Clalit Health Care 0 2 0 0 0 0 2
HudsonAlpha Institute for Biotechnology, HudsonAlpha Institute for Biotechnology 2 0 0 0 0 0 2
Imagene.me medical diagnostic laboratory, IMAGENE.ME SA 2 0 0 0 0 0 2
Institute of Human Genetics, FAU Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg 0 2 0 0 0 0 2
Laboratorio Biología Molecular, Sanatorio Americano 0 2 0 0 0 0 2
Molecular Genetics, Royal Melbourne Hospital 2 0 0 0 0 0 2
Regional Center For Medical Genetics Timis, Louis Turcanu Emergency Hospital for Children Timisoara 0 1 1 0 0 0 2
Zotz-Klimas Genetics Lab, MVZ Zotz Klimas 0 0 2 0 0 0 2
Agnes Ginges Centre for Molecular Cardiology, Centenary Institute 0 0 1 0 0 0 1
Arcensus 0 1 0 0 0 0 1
Breda Genetics srl, Breda Genetics srl 0 0 1 0 0 0 1
Broad Center for Mendelian Genomics, Broad Institute of MIT and Harvard 1 0 0 0 0 0 1
CENTOGENE GmbH and LLC - Guiding Precision Medicine 0 1 0 0 0 0 1
Center for Human Genetics and Genomic Medicine, Uniklinik Rwth Aachen 0 0 1 0 0 0 1
Center for Medical Genetics Ghent, University of Ghent 0 1 0 0 0 0 1
Clinical Biomedical Laboratory, Shriners Hospital For Children - Canada 0 1 0 0 0 0 1
Clinical Laboratory Sciences Program (CLSP), King Saud bin Abdulaziz University for Health Sciences (KSAU-HS) 1 0 0 0 0 0 1
Department of Obstetrics and Gynecology, Women and Children’s Hospital Affiliated to Ningbo University 0 1 0 0 0 0 1
Department of Pediatrics, Division of Medical Genetics, Faculty of Medicine Ramathibodi Hospital, Mahidol University 0 0 1 0 0 0 1
Diagnostics Services (NGS), CSIR - Centre For Cellular And Molecular Biology 0 0 1 0 0 0 1
Foundation for Research in Genetics and Endocrinology, FRIGE's Institute of Human Genetics 0 1 0 0 0 0 1
Geisinger Autism and Developmental Medicine Institute, Geisinger Health System 0 1 0 0 0 0 1
Genetics Department, Catlab 0 1 0 0 0 0 1
Greenwood Genetic Center Diagnostic Laboratories, Greenwood Genetic Center 0 1 0 0 0 0 1
Institute for Medical Genetics and Human Genetics, Charité - Universitätsmedizin Berlin 0 1 0 0 0 0 1
Institute of Clinical Chemistry and Institute of Clinical Molecular Biology, University Hospital Schleswig-Holstein, Campus Kiel 1 0 0 0 0 0 1
Institute of Human Genetics, University of Goettingen 0 1 0 0 0 0 1
Institute of Medical Genetics and Applied Genomics, University Hospital Tübingen 0 1 0 0 0 0 1
Laboratory for Molecular Medicine, Mass General Brigham Personalized Medicine 0 1 0 0 0 0 1
Laboratory of Cardiovascular Genetics, IRCCS Istituto Auxologico Italiano 0 1 0 0 0 0 1
Laboratory of Medical Genetics, National & Kapodistrian University of Athens 1 0 0 0 0 0 1
Lifecell International Pvt. Ltd 1 0 0 0 0 0 1
Mayo Clinic Laboratories, Mayo Clinic 0 0 1 0 0 0 1
New York Genome Center 0 0 1 0 0 0 1
North West Genomic Laboratory Hub, Manchester University NHS Foundation Trust 0 1 0 0 0 0 1
Provincial Medical Genetics Program of British Columbia, University of British Columbia 1 0 0 0 0 0 1
Rajaie Cardiovascular, Medical and Research Center, Iran University of Medical Sciences 0 1 0 0 0 0 1
Service of Pediatric Gastrohepatology and Metabolic Diseases, University of Medicine of Tirana 0 1 0 0 0 0 1
Servicio Canario de Salud, Hospital Universitario Nuestra Sra. de Candelaria 0 1 0 0 0 0 1
Suma Genomics 1 0 0 0 0 0 1
Variantyx, Inc. 1 0 0 0 0 0 1

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