ClinVar Miner

Variants studied for Breast-ovarian cancer, familial, susceptibility to, 4

Coded as:
Minimum submission review status: Collection method:
Minimum conflict level:
Gene type:

If a variant has more than one submission, it may be counted in more than one significance column. If this is the case, the total number of variants will be less than the sum of the other cells.

pathogenic likely pathogenic uncertain significance likely benign benign not provided total
164 120 774 584 273 7 1654

Gene and significance breakdown #

Total genes and gene combinations: 6
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Gene or gene combination pathogenic likely pathogenic uncertain significance likely benign benign not provided total
RAD51D, RAD51L3-RFFL 142 116 767 582 272 7 1618
RAD51D 21 4 5 0 0 0 30
FMN1 1 0 0 1 0 0 2
LOC130060715, RAD51D, RAD51L3-RFFL 0 0 0 1 1 0 2
FNDC8 0 0 1 0 0 0 1
FNDC8, LOC130060715, RAD51D, RAD51L3-RFFL 0 0 1 0 0 0 1

Submitter and significance breakdown #

Total submitters: 36
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Submitter pathogenic likely pathogenic uncertain significance likely benign benign not provided total
Labcorp Genetics (formerly Invitae), Labcorp 115 61 714 509 24 0 1423
Myriad Genetics, Inc. 79 52 12 145 259 0 547
Baylor Genetics 20 21 142 1 0 0 184
Counsyl 6 13 23 27 4 0 73
Fulgent Genetics, Fulgent Genetics 6 4 32 1 0 0 43
Mendelics 1 4 13 12 0 0 30
ARUP Laboratories, Molecular Genetics and Genomics, ARUP Laboratories 2 1 8 12 4 0 27
Department of Pathology and Laboratory Medicine, Sinai Health System 5 1 12 6 0 0 24
Hereditary Cancer Group, L’Institut d'Investigació Biomèdica de Bellvitge 10 6 5 1 0 0 22
MGZ Medical Genetics Center 2 2 10 0 0 0 14
KCCC/NGS Laboratory, Kuwait Cancer Control Center 0 2 11 0 0 0 13
Institute of Human Genetics, University of Leipzig Medical Center 2 2 5 0 1 0 10
Neuberg Centre For Genomic Medicine, NCGM 3 0 5 0 0 0 8
St. Jude Molecular Pathology, St. Jude Children's Research Hospital 0 1 6 0 0 0 7
OMIM 6 0 0 0 0 0 6
GenomeConnect - Invitae Patient Insights Network 0 0 0 0 0 5 5
Genesis Genomics 3 1 0 0 0 0 4
Genetics and Molecular Pathology, SA Pathology 0 0 4 0 0 0 4
Laboratorio de Genetica e Diagnostico Molecular, Hospital Israelita Albert Einstein 1 0 3 0 0 0 4
Department of Human Genetics, Hannover Medical School 1 0 2 0 0 0 3
Greenwood Genetic Center Diagnostic Laboratories, Greenwood Genetic Center 0 3 0 0 0 0 3
Juno Genomics, Hangzhou Juno Genomics, Inc 3 0 0 0 0 0 3
BRCAlab, Lund University 1 1 0 0 0 0 2
GenomeConnect, ClinGen 0 0 0 0 0 2 2
Variantyx, Inc. 1 1 0 0 0 0 2
3billion 0 0 1 0 0 0 1
Department of Molecular Diagnostics, Institute of Oncology Ljubljana 0 1 0 0 0 0 1
Division of Medical Genetics, University of Washington 0 0 1 0 0 0 1
Dr. med. U. Finckh, Human Genetics, Eurofins MVZ 0 0 1 0 0 0 1
Genetics and Genomic Medicine Centre, NeuroGen Healthcare, NeuroGen Healthcare 1 0 0 0 0 0 1
Genomic Medicine Center of Excellence, King Faisal Specialist Hospital and Research Centre 0 0 1 0 0 0 1
Human Genetics Bochum, Ruhr University Bochum 0 1 0 0 0 0 1
Institute of Human Genetics, Heidelberg University 1 0 0 0 0 0 1
Institute of Immunology and Genetics Kaiserslautern 1 0 0 0 0 0 1
University of Washington Department of Laboratory Medicine, University of Washington 0 0 0 1 0 0 1
Victorian Clinical Genetics Services, Murdoch Childrens Research Institute 1 0 0 0 0 0 1

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