ClinVar Miner

Significance terms

All terms in the following table are from SCVs (not RCVs) in the current ClinVar. Download table as spreadsheet

Significance term
affects
association
association not found
benign
benign/likely benign
confers sensitivity
conflicting data from submitters
drug response
established risk allele
likely benign
likely oncogenic
likely pathogenic
likely pathogenic, low penetrance
likely risk allele
no known pathogenicity
not provided
oncogenic
other
pathogenic
pathogenic, low penetrance
pathogenic/likely pathogenic
protective
risk factor
tier i - strong
tier ii - potential
tier iii - unknown
tier iv - benign/likely benign
uncertain risk allele
uncertain significance
vus-high
vus-low
vus-mid

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